SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
IG GAMMA-2A CHAIN C
REGION, A ALLELE
(Mus
musculus) 		4 / 7 TYR B  50
HIS A 436
THR B 101
ASN B  97
 None
 1.24A 1afsA-3zo0B:
undetectable		 1afsA-3zo0B:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
IG GAMMA-2A CHAIN C
REGION, A ALLELE
(Mus
musculus) 		4 / 7 TYR B  50
HIS A 436
THR B 101
ASN B  97
 None
 1.24A 1afsB-3zo0B:
undetectable		 1afsB-3zo0B:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		4 / 8 ILE B 130
GLY B  79
LEU B  54
PHE B  59
 None
 0.80A 2vctA-3zo0B:
undetectable		 2vctA-3zo0B:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		4 / 7 ILE B 130
GLY B  79
LEU B  54
PHE B  59
 None
 0.79A 2vctD-3zo0B:
undetectable		 2vctD-3zo0B:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 3zo0 IG GAMMA-2A CHAIN C
REGION, A ALLELE
E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus;
Mus
musculus) 		4 / 6 ASP B  77
HIS A 433
TYR B  50
ASN B  97
 None
 1.49A 2zs9A-3zo0B:
undetectable		 2zs9A-3zo0B:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 3zo0 IG GAMMA-2A CHAIN C
REGION, A ALLELE
(Mus
musculus) 		3 / 3 PRO A 271
LEU A 300
ARG A 293
 None
 0.73A 3aqiB-3zo0A:
undetectable		 3aqiB-3zo0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 10 PHE B  99
GLY B  79
VAL B  85
LEU B  93
PHE B  91
 None
 1.30A 3ay0B-3zo0B:
undetectable		 3ay0B-3zo0B:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3zo0 IG GAMMA-2A CHAIN C
REGION, A ALLELE
(Mus
musculus) 		5 / 12 ILE A 332
VAL A 273
SER A 304
VAL A 302
VAL A 263
 None
 1.20A 3iw1A-3zo0A:
undetectable		 3iw1A-3zo0A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 12 ASN B  19
SER B  20
ARG B  87
ASP B  42
ASN B  43
 None
 1.48A 3jb3A-3zo0B:
undetectable		 3jb3A-3zo0B:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		4 / 7 VAL B  85
VAL B  80
ASN B  97
GLY B  98
 None
 1.00A 3kmoB-3zo0B:
undetectable		 3kmoB-3zo0B:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		4 / 6 ARG B  29
PHE B 167
PRO B 165
LEU B  13
 None
 1.29A 3tgvB-3zo0B:
undetectable		 3tgvB-3zo0B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		4 / 6 ARG B  29
PHE B 167
PRO B 165
LEU B  13
 None
 1.29A 3tgvD-3zo0B:
undetectable		 3tgvD-3zo0B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 9 ARG B 164
THR B  17
VAL B  53
LEU B  13
ALA B  56
 None
 1.45A 3unaA-3zo0B:
undetectable		 3unaA-3zo0B:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 9 ARG B 164
THR B  17
VAL B  53
LEU B  13
ALA B  56
 None
 1.46A 3unaB-3zo0B:
undetectable		 3unaB-3zo0B:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 9 ARG B 164
THR B  17
VAL B  53
LEU B  13
ALA B  56
 None
 1.46A 3uncA-3zo0B:
undetectable		 3uncA-3zo0B:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 9 ARG B 164
THR B  17
VAL B  53
LEU B  13
ALA B  56
 None
 1.46A 3uncB-3zo0B:
undetectable		 3uncB-3zo0B:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 7 ARG B 164
THR B  17
VAL B  53
LEU B  13
ALA B  56
 None
 1.47A 3uniA-3zo0B:
undetectable		 3uniA-3zo0B:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		5 / 12 VAL B 169
SER B 174
GLY B  34
ASP B  35
GLY B 176
 None
 1.21A 4pevB-3zo0B:
undetectable		 4pevB-3zo0B:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		3 / 3 PRO B  51
MET B  52
TYR B  50
 None
 0.91A 4qa0B-3zo0B:
undetectable		 4qa0B-3zo0B:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		3 / 3 PRO B  51
MET B  52
TYR B  50
 None
 0.90A 4qa0A-3zo0B:
undetectable		 4qa0A-3zo0B:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21
(Mus
musculus) 		3 / 3 PRO B  51
MET B  52
TYR B  50
 None
 0.79A 4qa2B-3zo0B:
undetectable		 4qa2B-3zo0B:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3zo0 IG GAMMA-2A CHAIN C
REGION, A ALLELE
(Mus
musculus) 		4 / 4 LEU A 432
ILE A 377
HIS A 429
VAL A 427
 None
 1.33A 4xyzA-3zo0A:
undetectable		 4xyzA-3zo0A:
19.44