SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		5 / 9 LEU A  14
ILE A  15
LEU A  93
VAL A 101
GLY A  18
 None
 1.24A 1e7aB-3zogA:
undetectable		 1e7aB-3zogA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.18A 1zzrA-3zogA:
undetectable
1zzrB-3zogA:
undetectable		 1zzrA-3zogA:
17.95
1zzrB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.16A 1zzrA-3zogA:
undetectable
1zzrB-3zogA:
undetectable		 1zzrA-3zogA:
17.95
1zzrB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.18A 1zzuA-3zogA:
undetectable
1zzuB-3zogA:
undetectable		 1zzuA-3zogA:
17.95
1zzuB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.18A 1zzuA-3zogA:
undetectable
1zzuB-3zogA:
undetectable		 1zzuA-3zogA:
17.95
1zzuB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 8 ASP A  69
LYS A 151
PHE A 141
ASP A 138
 None
 1.05A 2aouA-3zogA:
undetectable		 2aouA-3zogA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2R6V_A_NCAA174_0
(UNCHARACTERIZED
PROTEIN PH0856)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		6 / 6 TYR A   8
HIS A  -7
ASP A  29
TRP A  30
ARG A  49
HIS A 124
 None
A2Q  A 200 (-4.2A)
FMN  A 173 (-3.3A)
A2Q  A 200 ( 3.3A)
FMN  A 173 ( 3.5A)
A2Q  A 200 ( 3.8A)
 0.22A 2r6vA-3zogA:
34.0		 2r6vA-3zogA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.18A 3dqrA-3zogA:
undetectable
3dqrB-3zogA:
undetectable		 3dqrA-3zogA:
17.95
3dqrB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.16A 3dqrA-3zogA:
undetectable
3dqrB-3zogA:
undetectable		 3dqrA-3zogA:
17.95
3dqrB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.17A 3jx2A-3zogA:
undetectable
3jx2B-3zogA:
undetectable		 3jx2A-3zogA:
17.95
3jx2B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.17A 3jx2A-3zogA:
undetectable
3jx2B-3zogA:
undetectable		 3jx2A-3zogA:
17.95
3jx2B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.19A 3jx3A-3zogA:
undetectable
3jx3B-3zogA:
undetectable		 3jx3A-3zogA:
17.95
3jx3B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.20A 3jx3A-3zogA:
undetectable
3jx3B-3zogA:
undetectable		 3jx3A-3zogA:
17.95
3jx3B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.19A 3jx4A-3zogA:
undetectable
3jx4B-3zogA:
undetectable		 3jx4A-3zogA:
17.95
3jx4B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.20A 3jx5A-3zogA:
undetectable
3jx5B-3zogA:
undetectable		 3jx5A-3zogA:
17.95
3jx5B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.13A 3jx6A-3zogA:
undetectable
3jx6B-3zogA:
undetectable		 3jx6A-3zogA:
17.95
3jx6B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 6 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.18A 3n61A-3zogA:
undetectable
3n61B-3zogA:
undetectable		 3n61A-3zogA:
17.95
3n61B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.17A 3n61A-3zogA:
undetectable
3n61B-3zogA:
undetectable		 3n61A-3zogA:
17.95
3n61B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.13A 3nljA-3zogA:
undetectable
3nljB-3zogA:
undetectable		 3nljA-3zogA:
17.95
3nljB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.14A 3nljA-3zogA:
undetectable
3nljB-3zogA:
undetectable		 3nljA-3zogA:
17.95
3nljB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.20A 3nlpA-3zogA:
undetectable
3nlpB-3zogA:
undetectable		 3nlpA-3zogA:
17.95
3nlpB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.12A 3nlqA-3zogA:
undetectable
3nlqB-3zogA:
undetectable		 3nlqA-3zogA:
17.95
3nlqB-3zogA:
17.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		7 / 7 TYR A   8
HIS A  -7
ASP A  29
TRP A  30
ARG A  49
HIS A 124
HIS A 155
 None
A2Q  A 200 (-4.2A)
FMN  A 173 (-3.3A)
A2Q  A 200 ( 3.3A)
FMN  A 173 ( 3.5A)
A2Q  A 200 ( 3.8A)
FMN  A 173 (-3.6A)
 0.11A 3zodA-3zogA:
34.3		 3zodA-3zogA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_A_HQEA200_1
(FLAVOREDOXIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 5 TYR A   8
TRP A  30
ARG A  49
HIS A 124
 None
A2Q  A 200 ( 3.3A)
FMN  A 173 ( 3.5A)
A2Q  A 200 ( 3.8A)
 0.47A 3zofA-3zogA:
24.1		 3zofA-3zogA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_B_HQEB200_1
(FLAVOREDOXIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 5 TYR A   8
TRP A  30
ARG A  49
HIS A 124
 None
A2Q  A 200 ( 3.3A)
FMN  A 173 ( 3.5A)
A2Q  A 200 ( 3.8A)
 0.45A 3zofB-3zogA:
23.9		 3zofB-3zogA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.19A 4cx3A-3zogA:
undetectable
4cx3B-3zogA:
undetectable		 4cx3A-3zogA:
17.95
4cx3B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.20A 4cx3A-3zogA:
undetectable
4cx3B-3zogA:
undetectable		 4cx3A-3zogA:
17.95
4cx3B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.19A 4cx4A-3zogA:
undetectable
4cx4B-3zogA:
undetectable		 4cx4A-3zogA:
17.95
4cx4B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.23A 4cx4A-3zogA:
undetectable
4cx4B-3zogA:
undetectable		 4cx4A-3zogA:
17.95
4cx4B-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 ALA A 107
LEU A 153
ARG A  11
ILE A 104
 None
 0.86A 4ubsA-3zogA:
undetectable		 4ubsA-3zogA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.18A 5addA-3zogA:
undetectable
5addB-3zogA:
undetectable		 5addA-3zogA:
17.95
5addB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 VAL A 132
VAL A  41
PHE A  61
GLU A 112
 None
 1.22A 5g0pA-3zogA:
undetectable
5g0pB-3zogA:
undetectable		 5g0pA-3zogA:
17.95
5g0pB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		4 / 7 PHE A  61
GLU A 112
VAL A 132
VAL A  41
 None
 1.18A 5g0pA-3zogA:
undetectable
5g0pB-3zogA:
undetectable		 5g0pA-3zogA:
17.95
5g0pB-3zogA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3zog FMN-BINDING PROTEIN
(Pyrococcus
horikoshii) 		5 / 12 THR A 163
ALA A  77
LEU A  68
ARG A  72
LEU A  14
 None
 1.32A 6ie8A-3zogA:
undetectable		 6ie8A-3zogA:
20.36