SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zpm LATHERIN
(Equus
caballus) 		5 / 12 SER A  93
VAL A  94
GLN A  43
THR A  39
ILE A 159
 None
 1.31A 2vdyB-3zpmA:
undetectable		 2vdyB-3zpmA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3zpm LATHERIN
(Equus
caballus) 		5 / 11 SER A   8
LEU A 179
LEU A  19
LEU A  73
LEU A  90
 None
 1.07A 2xn5A-3zpmA:
undetectable		 2xn5A-3zpmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3zpm LATHERIN
(Equus
caballus) 		5 / 12 ILE A  86
LEU A  90
LEU A  19
GLN A  17
VAL A 114
 None
 1.19A 3ix9B-3zpmA:
undetectable		 3ix9B-3zpmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3zpm LATHERIN
(Equus
caballus) 		4 / 5 LEU A  65
LEU A  92
LEU A  25
SER A  26
 None
 1.02A 3vhuA-3zpmA:
undetectable		 3vhuA-3zpmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zpm LATHERIN
(Equus
caballus) 		5 / 12 SER A  93
VAL A  94
GLN A  43
THR A  39
ILE A 159
 None
 1.40A 4c49B-3zpmA:
undetectable		 4c49B-3zpmA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zpm LATHERIN
(Equus
caballus) 		5 / 12 SER A  93
VAL A  94
GLN A  43
THR A  39
ILE A 159
 None
 1.36A 4c49C-3zpmA:
undetectable		 4c49C-3zpmA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3zpm LATHERIN
(Equus
caballus) 		5 / 12 ILE A  40
ALA A 154
LEU A 101
LYS A  97
PRO A  58
 None
 1.34A 4gh8B-3zpmA:
undetectable		 4gh8B-3zpmA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3zpm LATHERIN
(Equus
caballus) 		4 / 4 PHE A  77
ILE A  84
GLN A   2
ARG A 201
 None
 0.99A 5jm4B-3zpmA:
undetectable		 5jm4B-3zpmA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3zpm LATHERIN
(Equus
caballus) 		5 / 11 ALA A 173
PHE A  24
THR A 178
ILE A  88
LEU A 135
 None
 1.27A 6h1lB-3zpmA:
undetectable		 6h1lB-3zpmA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zpm LATHERIN
(Equus
caballus) 		4 / 8 ASP A  80
HIS A 132
ASP A  85
GLU A  76
 None
 1.00A 6mn4A-3zpmA:
undetectable		 6mn4A-3zpmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zpm LATHERIN
(Equus
caballus) 		4 / 8 ASP A  80
HIS A 132
ASP A  85
GLU A  76
 None
 0.81A 6mn4B-3zpmA:
undetectable		 6mn4B-3zpmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zpm LATHERIN
(Equus
caballus) 		4 / 8 ASP A  80
HIS A 132
ASP A  85
GLU A  76
 None
 0.99A 6mn4D-3zpmA:
undetectable		 6mn4D-3zpmA:
21.92