SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zpx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 THR A  23
PRO A  25
THR A  24
 None
 0.87A 1a7yB-3zpxA:
undetectable		 1a7yB-3zpxA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 GLU A 249
ALA A 244
SER A 148
 None
 0.60A 1errB-3zpxA:
undetectable		 1errB-3zpxA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 8 GLY A 191
LEU A 214
VAL A 346
PHE A 324
 None
 1.22A 1gsfA-3zpxA:
undetectable		 1gsfA-3zpxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 8 GLY A 191
LEU A 214
VAL A 346
PHE A 324
 None
 1.22A 1gsfB-3zpxA:
undetectable		 1gsfB-3zpxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 8 GLY A 191
LEU A 214
VAL A 346
PHE A 324
 None
 1.22A 1gsfD-3zpxA:
undetectable		 1gsfD-3zpxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 5 LEU A 214
VAL A 346
TYR A 345
ARG A 326
 None
 1.31A 1nw3A-3zpxA:
undetectable		 1nw3A-3zpxA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 THR A  23
PRO A  25
THR A  24
 None
 0.86A 1unjF-3zpxA:
undetectable		 1unjF-3zpxA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 ASN A 195
TRP A 192
GLN A 349
 None
 1.18A 1xoqA-3zpxA:
undetectable		 1xoqA-3zpxA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 10 SER A  89
PHE A  88
TYR A 385
LEU A 381
TRP A 129
 None
 1.35A 2b8jB-3zpxA:
2.1		 2b8jB-3zpxA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 12 LEU A 166
ASN A 168
GLY A 162
GLY A  34
LEU A 172
 None
 0.91A 2egvA-3zpxA:
undetectable		 2egvA-3zpxA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 12 LEU A 166
ASN A 168
GLY A 162
GLY A  34
LEU A 172
 None
 0.96A 2egvB-3zpxA:
undetectable		 2egvB-3zpxA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 6 LEU A 295
ASP A 292
ILE A 252
ARG A 255
 None
 1.04A 2rlfB-3zpxA:
undetectable
2rlfC-3zpxA:
undetectable		 2rlfB-3zpxA:
8.31
2rlfC-3zpxA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 9 ILE A 125
LEU A 371
GLU A 370
LEU A 374
TYR A  90
 None
 1.33A 3f78A-3zpxA:
4.0		 3f78A-3zpxA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 9 ILE A 125
LEU A 371
GLU A 370
LEU A 374
TYR A  90
 None
 1.39A 3f78B-3zpxA:
3.8		 3f78B-3zpxA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 GLU A 370
GLU A 122
TRP A 329
 None
 1.00A 3hrdA-3zpxA:
undetectable
3hrdE-3zpxA:
undetectable
3hrdF-3zpxA:
undetectable		 3hrdA-3zpxA:
22.57
3hrdE-3zpxA:
22.57
3hrdF-3zpxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 6 SER A 140
ASP A 161
TYR A  59
PRO A 145
 None
 1.15A 3jqaC-3zpxA:
4.5		 3jqaC-3zpxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 6 SER A 140
ASP A 161
TYR A  59
PRO A 145
 None
 1.17A 3jqaD-3zpxA:
3.9		 3jqaD-3zpxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 ASN A  63
GLU A 154
ARG A 146
 None
 1.02A 3wxoA-3zpxA:
undetectable		 3wxoA-3zpxA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 GLU A 370
TYR A 183
SER A 184
 None
 0.80A 4at0A-3zpxA:
1.3		 4at0A-3zpxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 12 ALA A 236
SER A 239
VAL A 238
SER A 288
PHE A 222
 None
 1.28A 4c49A-3zpxA:
undetectable		 4c49A-3zpxA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 12 LEU A 241
ALA A 242
LEU A 256
ILE A 290
GLY A 260
 None
 0.96A 4dm8B-3zpxA:
undetectable		 4dm8B-3zpxA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 GLN A  58
THR A  24
THR A  23
 None
 0.82A 4fu9A-3zpxA:
undetectable		 4fu9A-3zpxA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3zpx LIPASE
(Ustilago
maydis) 		3 / 3 GLN A  58
THR A  24
THR A  23
 None
 0.82A 4fufA-3zpxA:
undetectable		 4fufA-3zpxA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 7 MET A 157
GLU A 154
GLU A 155
GLU A 308
 None
 1.35A 4r87I-3zpxA:
0.3		 4r87I-3zpxA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 4 VAL A 263
ILE A 290
ASN A 226
VAL A 238
 None
 1.35A 5ajqA-3zpxA:
0.0		 5ajqA-3zpxA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 6 ALA A 236
SER A 239
GLN A  98
SER A 269
 None
 1.12A 5c6pA-3zpxA:
undetectable		 5c6pA-3zpxA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 7 GLY A 185
GLY A 212
TYR A  90
ALA A 189
 None
 0.87A 5e26C-3zpxA:
undetectable
5e26D-3zpxA:
undetectable		 5e26C-3zpxA:
21.61
5e26D-3zpxA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3zpx LIPASE
(Ustilago
maydis) 		5 / 12 ALA A 234
ALA A 286
LEU A 289
PHE A 230
GLY A 232
 None
 1.34A 5jglA-3zpxA:
undetectable		 5jglA-3zpxA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3zpx LIPASE
(Ustilago
maydis) 		4 / 6 LEU A 295
VAL A 301
LEU A 305
VAL A 248
 None
 0.77A 5x7zA-3zpxA:
undetectable		 5x7zA-3zpxA:
16.11