SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		3 / 3 LEU A 376
TRP A 299
TYR A 374
 None
 1.00A 3aicA-3zpyA:
undetectable		 3aicA-3zpyA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		3 / 3 LEU A 376
TRP A 299
TYR A 374
 None
 0.99A 3aicG-3zpyA:
undetectable		 3aicG-3zpyA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		5 / 12 ILE A 215
THR A 233
ASP A 231
ILE A 208
ASN A 211
 None
 1.17A 3kpdB-3zpyA:
undetectable		 3kpdB-3zpyA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		5 / 12 HIS A 323
ILE A 322
ASP A 291
LEU A 410
GLY A 290
 None
 1.37A 4foxE-3zpyA:
undetectable		 4foxE-3zpyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		4 / 6 ASP A 252
LYS A 439
THR A 251
TYR A 257
 None
 1.49A 4w5tA-3zpyA:
undetectable		 4w5tA-3zpyA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		4 / 6 TYR A 420
ASP A 335
ILE A 322
TYR A 414
 None
 1.25A 5igyA-3zpyA:
undetectable		 5igyA-3zpyA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		3 / 3 TYR A 228
PRO A 273
LEU A 264
 None
 0.82A 6beoA-3zpyA:
undetectable		 6beoA-3zpyA:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		5 / 12 TYR A 420
LEU A 306
GLY A 315
GLN A 341
ASP A 336
 None
 1.23A 6bxlA-3zpyA:
undetectable		 6bxlA-3zpyA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		5 / 12 TRP A 213
GLY A 418
GLY A 320
PHE A 258
VAL A 301
 None
 1.24A 6clxA-3zpyA:
undetectable		 6clxA-3zpyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zpy ALGINATE LYASE,
FAMILY PL7
(Zobellia
galactanivorans) 		4 / 7 HIS A 445
ARG A 278
HIS A 323
GLU A 279
 None
 1.40A 6mn4F-3zpyA:
undetectable		 6mn4F-3zpyA:
18.25