SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		4 / 7 TYR A 153
TYR A 312
GLU A 154
TRP A 234
 None
 1.33A 3cotA-3zqbA:
undetectable		 3cotA-3zqbA:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		4 / 7 ILE A 142
VAL A 323
LEU A 326
SER A 327
 None
 0.41A 3r9vA-3zqbA:
19.6
3r9vB-3zqbA:
15.6		 3r9vA-3zqbA:
39.60
3r9vB-3zqbA:
39.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		5 / 11 GLN A  24
THR A  28
LEU A  31
TYR A  47
TYR A  54
 None
 0.38A 3zqeA-3zqbA:
36.9
3zqeB-3zqbA:
27.5		 3zqeA-3zqbA:
100.00
3zqeB-3zqbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		3 / 3 GLU A 237
TRP A 234
LYS A  50
 None
 1.02A 4k7aA-3zqbA:
undetectable		 4k7aA-3zqbA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		4 / 6 TYR A 149
ASN A  59
GLU A 237
PHE A 215
 None
 1.02A 4twdG-3zqbA:
undetectable
4twdH-3zqbA:
undetectable		 4twdG-3zqbA:
22.41
4twdH-3zqbA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3zqb PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD
(Salmonella
enterica) 		4 / 8 GLN A  26
ALA A  46
GLN A  48
SER A  49
 None
 1.09A 5km8A-3zqbA:
undetectable
5km8B-3zqbA:
undetectable		 5km8A-3zqbA:
18.77
5km8B-3zqbA:
18.77