SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zre'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 10 PRO A  54
THR A  58
CYH A  61
LEU A 127
ARG A 133
 None
 0.89A 1h4oA-3zreA:
18.2
1h4oB-3zreA:
18.3		 1h4oA-3zreA:
23.58
1h4oB-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
CYH A  61
ARG A 133
 None
 0.53A 1h4oB-3zreA:
18.3		 1h4oB-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 THR A  58
CYH A  61
ARG A 133
THR A 154
 None
 0.87A 1h4oB-3zreA:
18.3		 1h4oB-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
CYH A  61
ARG A 133
 None
 0.44A 1h4oG-3zreA:
18.1		 1h4oG-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 9 PRO A  54
THR A  58
CYH A  61
LEU A 127
ARG A 133
 None
 0.92A 1h4oH-3zreA:
18.2		 1h4oH-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 9 PRO A  54
THR A  58
CYH A  61
LEU A 127
ARG A 133
 None
 0.92A 1hd2A-3zreA:
18.2		 1hd2A-3zreA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
CYH A  61
ARG A 133
 None
 0.51A 1oc3A-3zreA:
18.2		 1oc3A-3zreA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 6 LEU A 127
ALA A 132
LEU A 130
SER A  85
 None
 1.18A 1tyrA-3zreA:
undetectable		 1tyrA-3zreA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 5 ASP A  57
GLY A  96
ALA A  62
ILE A  56
 None
 0.95A 2aofA-3zreA:
undetectable		 2aofA-3zreA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
VAL A  60
ARG A 133
 None
 0.58A 2v32C-3zreA:
16.3
2v32D-3zreA:
16.8		 2v32C-3zreA:
23.50
2v32D-3zreA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
VAL A  60
ARG A 133
 None
 0.58A 2v41C-3zreA:
16.7
2v41D-3zreA:
16.8		 2v41C-3zreA:
23.50
2v41D-3zreA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
VAL A  60
ARG A 133
 None
 0.54A 2v41C-3zreA:
16.7
2v41D-3zreA:
16.8		 2v41C-3zreA:
23.50
2v41D-3zreA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A  54
THR A  58
VAL A  60
ARG A 133
 None
 0.53A 2v41G-3zreA:
16.4
2v41H-3zreA:
16.4		 2v41G-3zreA:
23.50
2v41H-3zreA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 9 ASP A  57
ALA A  90
GLY A  96
ALA A  62
ILE A  56
 None
 1.01A 3ektB-3zreA:
undetectable		 3ektB-3zreA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 10 ASP A  57
ALA A  90
GLY A  96
ALA A  62
ILE A  56
 None
 0.92A 3ekwA-3zreA:
undetectable		 3ekwA-3zreA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		5 / 11 VAL A   5
ALA A 134
THR A 154
THR A 155
PRO A 157
 None
 1.12A 3mdzA-3zreA:
undetectable		 3mdzA-3zreA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 8 THR A 131
ILE A  52
VAL A 136
GLY A 119
 None
 0.84A 4eq4B-3zreA:
undetectable		 4eq4B-3zreA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 7 LEU A 127
ALA A 132
LEU A 130
SER A  85
 None
 1.15A 4iklA-3zreA:
undetectable
4iklB-3zreA:
undetectable		 4iklA-3zreA:
21.47
4iklB-3zreA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 7 ASP A  86
SER A  64
PHE A  53
ASP A  57
 None
 1.32A 5a1iA-3zreA:
undetectable		 5a1iA-3zreA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 6 LEU A 127
ALA A 132
LEU A 130
SER A  85
 None
 1.18A 5a6iA-3zreA:
undetectable		 5a6iA-3zreA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zre THIOL PEROXIDASE
(Yersinia
pseudotuberculos
is) 		4 / 7 ASP A  86
SER A  64
PHE A  53
ASP A  57
 None
 1.32A 6g6rA-3zreA:
undetectable		 6g6rA-3zreA:
19.35