SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zrg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K74_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3zrg	PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE (Phytophthora infestans)	6 / 12	ILE A 86 ALA A 89 ALA A 90 LEU A 99 ALA A 95 VAL A 73	None None None BR A1122 ( 4.5A) None None	1.48A	1k74A-3zrgA: undetectable	1k74A-3zrgA: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3zrg	PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE (Phytophthora infestans)	6 / 12	ILE A 86 ALA A 89 ALA A 90 LEU A 99 ALA A 95 VAL A 73	None None None BR A1122 ( 4.5A) None None	1.48A	1xdkE-3zrgA: undetectable	1xdkE-3zrgA: 15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_A_9CRA503_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3zrg	PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE (Phytophthora infestans)	6 / 12	ILE A 86 ALA A 89 ALA A 90 LEU A 99 ALA A 95 VAL A 73	None None None BR A1122 ( 4.5A) None None	1.40A	5uanA-3zrgA: undetectable	5uanA-3zrgA: 10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3zrg	PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE (Phytophthora infestans)	6 / 12	ILE A 86 ALA A 89 ALA A 90 LEU A 99 ALA A 95 VAL A 73	None None None BR A1122 ( 4.5A) None None	1.49A	5z12B-3zrgA: undetectable	5z12B-3zrgA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_C_9CRC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3zrg	PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE (Phytophthora infestans)	6 / 12	ILE A 86 ALA A 89 ALA A 90 LEU A 99 ALA A 95 VAL A 73	None None None BR A1122 ( 4.5A) None None	1.49A	5z12C-3zrgA: undetectable	5z12C-3zrgA: 22.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1K74_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3zrg","PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE","Phytophthora infestans",6,"ILE A  86;ALA A  89;ALA A  90;LEU A  99;ALA A  95;VAL A  73","None;None;None; BR A1122 ( 4.5A);None;None","1.48A","1k74A-3zrgA:undetectable","1k74A-3zrgA:15.55"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3zrg","PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE","Phytophthora infestans",6,"ILE A  86;ALA A  89;ALA A  90;LEU A  99;ALA A  95;VAL A  73","None;None;None; BR A1122 ( 4.5A);None;None","1.48A","1xdkE-3zrgA:undetectable","1xdkE-3zrgA:15.97"],["5UAN_A_9CRA503_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3zrg","PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE","Phytophthora infestans",6,"ILE A  86;ALA A  89;ALA A  90;LEU A  99;ALA A  95;VAL A  73","None;None;None; BR A1122 ( 4.5A);None;None","1.40A","5uanA-3zrgA:undetectable","5uanA-3zrgA:10.83"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3zrg","PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE","Phytophthora infestans",6,"ILE A  86;ALA A  89;ALA A  90;LEU A  99;ALA A  95;VAL A  73","None;None;None; BR A1122 ( 4.5A);None;None","1.49A","5z12B-3zrgA:undetectable","5z12B-3zrgA:22.50"],["5Z12_C_9CRC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3zrg","PEXRD2 FAMILY SECRETED RXLR EFFECTOR PEPTIDE, PUTATIVE","Phytophthora infestans",6,"ILE A  86;ALA A  89;ALA A  90;LEU A  99;ALA A  95;VAL A  73","None;None;None; BR A1122 ( 4.5A);None;None","1.49A","5z12C-3zrgA:undetectable","5z12C-3zrgA:22.50"]]