SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 115
PHE A 148
LEU A  45
LEU A  91
LEU A  95
 None
 1.12A 1dtlA-3zriA:
undetectable		 1dtlA-3zriA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A 135
LEU A 132
SER A 129
 None
 0.67A 1tlmA-3zriA:
undetectable		 1tlmA-3zriA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		5 / 12 TYR A 127
VAL A  53
SER A 113
ILE A 116
LEU A  45
 None
 1.20A 1z9hA-3zriA:
undetectable		 1z9hA-3zriA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		5 / 12 TYR A 127
VAL A  53
SER A 113
ILE A 116
LEU A  45
 None
 1.19A 1z9hB-3zriA:
undetectable		 1z9hB-3zriA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		5 / 12 TYR A 127
VAL A  53
SER A 113
ILE A 116
LEU A  45
 None
 1.20A 1z9hC-3zriA:
undetectable		 1z9hC-3zriA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		4 / 7 VAL A  92
ILE A 116
GLY A 114
LEU A 144
 None
 0.88A 3bjwB-3zriA:
undetectable		 3bjwB-3zriA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		4 / 7 VAL A  92
ILE A 116
GLY A 114
LEU A 144
 None
 0.85A 3bjwF-3zriA:
undetectable		 3bjwF-3zriA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 128
SER A 129
GLU A  39
LEU A  42
ASP A  43
 None
 1.24A 3ko0G-3zriA:
undetectable
3ko0H-3zriA:
undetectable
3ko0I-3zriA:
undetectable
3ko0J-3zriA:
undetectable		 3ko0G-3zriA:
21.59
3ko0H-3zriA:
21.59
3ko0I-3zriA:
21.59
3ko0J-3zriA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 3zri CLPB PROTEIN
(Vibrio
cholerae) 		4 / 6 ASP A  43
LEU A 128
SER A 129
PHE A 136
 None
 1.08A 6ekuA-3zriA:
undetectable		 6ekuA-3zriA:
13.10