SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zs6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ALA A 328
LEU A 329
LEU A 385
LEU A 320
LEU A 313
 None
 1.12A 1errB-3zs6A:
undetectable		 1errB-3zs6A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 ALA A  49
TYR A 531
ILE A 552
ASP A 279
 None
 0.94A 1upfC-3zs6A:
undetectable		 1upfC-3zs6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 ILE A 292
SER A 293
SER A 530
LEU A 527
 None
 0.96A 2cdqA-3zs6A:
undetectable		 2cdqA-3zs6A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A 546
TYR A 260
ILE A 255
ASP A  81
 None
 1.22A 2x45B-3zs6A:
undetectable		 2x45B-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A 546
TYR A 280
VAL A 532
ILE A 255
 None
 1.12A 2x45B-3zs6A:
undetectable		 2x45B-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A 546
TYR A 260
ILE A 255
ASP A  81
 None
 1.22A 2x45C-3zs6A:
undetectable		 2x45C-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A 546
TYR A 280
VAL A 532
ILE A 255
 None
 1.13A 2x45C-3zs6A:
undetectable		 2x45C-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 PHE A 113
THR A 128
VAL A 127
VAL A 183
ILE A 173
 None
 1.13A 3elzA-3zs6A:
undetectable		 3elzA-3zs6A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 THR A 128
VAL A 127
VAL A 183
ILE A 173
THR A 196
 None
 1.22A 3elzB-3zs6A:
undetectable		 3elzB-3zs6A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 128
VAL A 127
VAL A 183
ILE A 173
THR A 196
 None
 1.25A 3elzC-3zs6A:
undetectable		 3elzC-3zs6A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 128
VAL A 127
VAL A 183
ILE A 173
THR A 196
 None
 1.32A 3em0A-3zs6A:
undetectable		 3em0A-3zs6A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 10 ASP A 525
ASN A 405
ASP A 266
ILE A 284
GLY A 288
 None
 1.39A 3myuA-3zs6A:
1.3		 3myuA-3zs6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 ARG A 499
TYR A 457
TYR A 191
LEU A 195
 None
 1.42A 4f8yA-3zs6A:
undetectable
4f8yB-3zs6A:
undetectable		 4f8yA-3zs6A:
17.80
4f8yB-3zs6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 9 PRO A 367
PRO A 515
TYR A 514
GLY A 352
TYR A 351
 None
 1.23A 4fimA-3zs6A:
4.6		 4fimA-3zs6A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ASN A  76
LEU A 151
GLY A  79
ASN A 225
GLY A 226
 None
 1.13A 4n09A-3zs6A:
undetectable		 4n09A-3zs6A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 LEU A 466
ILE A 467
LEU A 353
TYR A 310
 None
 0.94A 4w5nA-3zs6A:
undetectable		 4w5nA-3zs6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 4 GLY A 346
LEU A 527
PHE A 296
ILE A 292
 None
 0.90A 4xv2A-3zs6A:
undetectable		 4xv2A-3zs6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ALA A 119
GLY A  85
GLY A 226
LEU A 201
LEU A  86
 None
 1.04A 5c0oH-3zs6A:
undetectable		 5c0oH-3zs6A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 LEU A 151
ALA A 197
LEU A 201
VAL A  95
 None
 1.14A 5cr1A-3zs6A:
undetectable		 5cr1A-3zs6A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 THR A 339
THR A 343
PHE A 289
 None
 0.66A 5cxvA-3zs6A:
undetectable		 5cxvA-3zs6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 TYR A 228
SER A 546
GLY A 533
VAL A 258
LEU A 551
 None
 1.23A 5g6sB-3zs6A:
undetectable
5g6sC-3zs6A:
undetectable		 5g6sB-3zs6A:
22.00
5g6sC-3zs6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 4 LEU A 115
LEU A  86
GLY A  85
GLU A  84
 None
 1.05A 5hhjA-3zs6A:
undetectable		 5hhjA-3zs6A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 9 GLN A 344
PHE A 289
PRO A 302
LEU A 300
ILE A 284
 None
 1.28A 5i73A-3zs6A:
undetectable		 5i73A-3zs6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 LEU A 230
THR A 259
THR A  55
ASP A  53
 None
 1.11A 5jq7B-3zs6A:
undetectable		 5jq7B-3zs6A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 LEU A 306
ILE A 150
THR A 462
MET A 198
 None
 1.31A 5ljeA-3zs6A:
undetectable		 5ljeA-3zs6A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 THR A 110
HIS A 105
ALA A 107
ASP A 109
 None
 1.29A 5mfxA-3zs6A:
undetectable		 5mfxA-3zs6A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 TRP A  73
MET A 543
ASN A 539
 None
 0.84A 5uc1B-3zs6A:
undetectable		 5uc1B-3zs6A:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 TRP A  73
MET A 543
ASN A 539
 None
 0.83A 5uc1A-3zs6A:
undetectable		 5uc1A-3zs6A:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 GLY A 287
ILE A 284
GLN A 295
ASP A 406
 None
 0.98A 5vlmH-3zs6A:
undetectable		 5vlmH-3zs6A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 VAL A 446
ALA A 449
GLN A 440
 None
 0.51A 6gb9A-3zs6A:
undetectable		 6gb9A-3zs6A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A 333
ILE A 448
ALA A 381
LEU A 320
LEU A 423
 None
 1.22A 6ie8A-3zs6A:
undetectable		 6ie8A-3zs6A:
17.40