SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 8 THR A 149
GLY A 151
ARG A 184
THR A 188
 None
 0.84A 1oc3A-3zseA:
undetectable		 1oc3A-3zseA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 12 TYR A 129
VAL A 226
TYR A  77
ILE A 212
LEU A 228
 None
 1.45A 1z9hA-3zseA:
undetectable		 1z9hA-3zseA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 12 TYR A 129
VAL A 226
TYR A  77
ILE A 212
LEU A 228
 None
 1.45A 1z9hB-3zseA:
undetectable		 1z9hB-3zseA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 12 TYR A 129
VAL A 226
TYR A  77
ILE A 212
LEU A 228
 None
 1.45A 1z9hC-3zseA:
undetectable		 1z9hC-3zseA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 5 ILE A 189
HIS A 194
TYR A 103
ARG A 180
 None
 1.20A 3b9mA-3zseA:
undetectable		 3b9mA-3zseA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 6 VAL A  88
ARG A 161
TRP A  60
TRP A 120
 FXP  A1207 (-4.7A)
FXP  A1207 (-4.1A)
FXP  A1207 (-3.9A)
FXP  A1207 (-4.6A)
 1.48A 3jx4A-3zseA:
undetectable
3jx4B-3zseA:
undetectable		 3jx4A-3zseA:
17.36
3jx4B-3zseA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 7 TYR A 129
TYR A 118
TYR A 210
TYR A  77
 None
FXP  A1207 (-4.7A)
FXP  A1207 (-4.7A)
None
 1.26A 3ku9B-3zseA:
undetectable		 3ku9B-3zseA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 7 TYR A 128
LEU A 117
TRP A  93
TYR A  77
 None
None
EDO  A1234 (-4.1A)
None
 1.34A 4f8yC-3zseA:
undetectable
4f8yD-3zseA:
undetectable		 4f8yC-3zseA:
19.91
4f8yD-3zseA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 7 TYR A 114
TYR A  77
GLU A 216
PHE A 107
 EDO  A1232 (-4.4A)
None
EDO  A1232 (-3.7A)
None
 1.10A 5aclA-3zseA:
undetectable		 5aclA-3zseA:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 8 THR A 140
THR A 159
ARG A 161
GLN A 175
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
 0.78A 5tzoA-3zseA:
28.4		 5tzoA-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 8 TYR A 157
THR A 159
ARG A 161
GLN A 175
TRP A 177
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
None
 0.48A 5tzoA-3zseA:
28.4		 5tzoA-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		7 / 12 VAL A  88
TRP A 120
TYR A 129
PRO A 165
TRP A 177
TYR A 210
GLY A 217
 FXP  A1207 (-4.7A)
FXP  A1207 (-4.6A)
None
FXP  A1207 (-3.7A)
None
FXP  A1207 (-4.7A)
None
 0.78A 5tzoA-3zseA:
28.4		 5tzoA-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		6 / 12 VAL A  88
TRP A 120
TYR A 129
TRP A 177
TYR A 210
GLY A 217
 FXP  A1207 (-4.7A)
FXP  A1207 (-4.6A)
None
None
FXP  A1207 (-4.7A)
None
 0.79A 5tzoB-3zseA:
28.6		 5tzoB-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		3 / 3 ARG A 161
PRO A 165
TYR A 218
 FXP  A1207 (-4.1A)
FXP  A1207 (-3.7A)
EDO  A1232 (-3.8A)
 0.53A 5tzoB-3zseA:
28.6		 5tzoB-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 8 THR A 140
THR A 159
ARG A 161
GLN A 175
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
 0.81A 5tzoB-3zseA:
28.6		 5tzoB-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 8 TYR A 157
THR A 159
ARG A 161
GLN A 175
TRP A 177
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
None
 0.33A 5tzoB-3zseA:
28.6		 5tzoB-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		7 / 12 VAL A  88
TRP A 120
TYR A 129
PRO A 165
TRP A 177
TYR A 210
GLY A 217
 FXP  A1207 (-4.7A)
FXP  A1207 (-4.6A)
None
FXP  A1207 (-3.7A)
None
FXP  A1207 (-4.7A)
None
 0.86A 5tzoC-3zseA:
28.4		 5tzoC-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 8 THR A 140
THR A 159
ARG A 161
GLN A 175
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
 0.78A 5tzoC-3zseA:
28.4		 5tzoC-3zseA:
55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		5 / 8 TYR A 157
THR A 159
ARG A 161
GLN A 175
TRP A 177
 None
None
FXP  A1207 (-4.1A)
FXP  A1207 (-4.3A)
None
 0.43A 5tzoC-3zseA:
28.4		 5tzoC-3zseA:
55.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 5 GLY A 135
THR A 136
SER A 221
SER A 220
 None
 0.81A 6jmjA-3zseA:
undetectable		 6jmjA-3zseA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 7 GLY A 135
THR A 136
SER A 221
SER A 220
 None
 0.80A 6jnhA-3zseA:
undetectable		 6jnhA-3zseA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zse ENDO-1,4-BETA-XYLANA
SE
(Thermobifida
fusca) 		4 / 6 GLY A 135
THR A 136
SER A 221
SER A 220
 None
 0.81A 6jogA-3zseA:
undetectable		 6jogA-3zseA:
18.35