SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zu0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 9 ALA A 150
THR A 123
HIS A 227
ILE A 180
GLY A 125
 None
None
ZN  A1595 (-3.2A)
None
None
 1.21A 1gtfR-3zu0A:
undetectable
1gtfS-3zu0A:
undetectable		 1gtfR-3zu0A:
9.79
1gtfS-3zu0A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		6 / 11 ARG A 397
GLY A 434
ARG A 437
ASN A 538
GLY A 488
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.4A)
A12  A1598 (-2.6A)
A12  A1598 ( 4.4A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 1.14A 1ho5A-3zu0A:
34.3		 1ho5A-3zu0A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		7 / 11 ARG A 397
GLY A 434
ARG A 437
PHE A 456
ASN A 458
GLY A 488
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.4A)
A12  A1598 (-2.6A)
A12  A1598 (-3.4A)
A12  A1598 (-3.1A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 0.58A 1ho5A-3zu0A:
34.3		 1ho5A-3zu0A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 10 ARG A 397
GLY A 434
ARG A 437
ASN A 538
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.4A)
A12  A1598 (-2.6A)
A12  A1598 ( 4.4A)
A12  A1598 (-2.7A)
 1.17A 1ho5B-3zu0A:
34.2		 1ho5B-3zu0A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		7 / 10 ARG A 397
GLY A 434
ARG A 437
PHE A 456
ASN A 458
GLY A 488
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.4A)
A12  A1598 (-2.6A)
A12  A1598 (-3.4A)
A12  A1598 (-3.1A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 0.58A 1ho5B-3zu0A:
34.2		 1ho5B-3zu0A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 SER A 192
THR A 188
PHE A 129
GLY A 132
 None
 1.31A 1icrA-3zu0A:
undetectable
1icrB-3zu0A:
undetectable		 1icrA-3zu0A:
18.07
1icrB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 SER A 192
THR A 188
PHE A 129
GLY A 195
 None
 1.33A 1icrA-3zu0A:
undetectable
1icrB-3zu0A:
undetectable		 1icrA-3zu0A:
18.07
1icrB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 195
SER A 192
THR A 188
PHE A 129
 None
 1.33A 1icrA-3zu0A:
undetectable
1icrB-3zu0A:
undetectable		 1icrA-3zu0A:
18.07
1icrB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 132
SER A 192
THR A 188
PHE A 129
 None
 1.20A 1icuC-3zu0A:
undetectable
1icuD-3zu0A:
undetectable		 1icuC-3zu0A:
18.07
1icuD-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 195
SER A 192
THR A 188
PHE A 129
 None
 1.38A 1icuC-3zu0A:
undetectable
1icuD-3zu0A:
undetectable		 1icuC-3zu0A:
18.07
1icuD-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 132
SER A 192
THR A 188
PHE A 129
 None
 1.25A 1icvA-3zu0A:
undetectable
1icvB-3zu0A:
undetectable		 1icvA-3zu0A:
18.07
1icvB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 195
SER A 192
THR A 188
PHE A 129
 None
 1.37A 1icvA-3zu0A:
undetectable
1icvB-3zu0A:
undetectable		 1icvA-3zu0A:
18.07
1icvB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 SER A 192
THR A 188
PHE A 129
GLY A 132
 None
 1.29A 1icvC-3zu0A:
undetectable
1icvD-3zu0A:
undetectable		 1icvC-3zu0A:
18.07
1icvD-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 132
SER A 192
THR A 188
PHE A 129
 None
 1.26A 1icvC-3zu0A:
undetectable
1icvD-3zu0A:
undetectable		 1icvC-3zu0A:
18.07
1icvD-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 GLY A 195
SER A 192
THR A 188
PHE A 129
 None
 1.32A 1icvC-3zu0A:
undetectable
1icvD-3zu0A:
undetectable		 1icvC-3zu0A:
18.07
1icvD-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 10 ASP A  94
SER A 226
SER A 149
ALA A 150
ASP A 250
 ZN  A1595 (-2.4A)
None
None
None
ZN  A1595 ( 3.2A)
 1.48A 1m4dA-3zu0A:
undetectable		 1m4dA-3zu0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 ASP A  94
HIS A 127
HIS A  46
 ZN  A1595 (-2.4A)
PO4  A1597 ( 4.0A)
ZN  A1596 (-3.3A)
 0.68A 1oe1A-3zu0A:
undetectable		 1oe1A-3zu0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 ASP A  94
HIS A 127
HIS A  46
 ZN  A1595 (-2.4A)
PO4  A1597 ( 4.0A)
ZN  A1596 (-3.3A)
 0.68A 1oe3A-3zu0A:
undetectable		 1oe3A-3zu0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 10 ASP A 244
GLY A 306
ILE A 180
LEU A 214
ALA A 178
 None
 1.15A 1x7pA-3zu0A:
undetectable
1x7pB-3zu0A:
undetectable		 1x7pA-3zu0A:
20.20
1x7pB-3zu0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 THR A 248
GLY A 249
GLY A 125
THR A 123
ILE A 246
 None
 1.41A 2akeA-3zu0A:
undetectable		 2akeA-3zu0A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 242
LYS A 215
GLY A 218
THR A 171
 None
 0.98A 2aouA-3zu0A:
undetectable		 2aouA-3zu0A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 LEU A 224
ASN A 233
VAL A 240
ALA A 207
 None
 1.13A 2cizA-3zu0A:
undetectable		 2cizA-3zu0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 6 TYR A 253
TYR A 269
GLY A 229
ASP A 250
 None
None
None
ZN  A1595 ( 3.2A)
 1.29A 2g72A-3zu0A:
undetectable		 2g72A-3zu0A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 0.98A 2obvA-3zu0A:
undetectable		 2obvA-3zu0A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		6 / 12 LEU A 182
ALA A 211
ASP A 242
ILE A 219
PRO A 166
ILE A 180
 None
 1.43A 2qakA-3zu0A:
undetectable		 2qakA-3zu0A:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 VAL A 591
THR A 487
ASN A 405
SER A 404
PHE A 490
 None
 1.17A 2vdyB-3zu0A:
undetectable		 2vdyB-3zu0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 ILE A 354
LEU A 263
ASN A  57
VAL A 317
VAL A  65
 None
 1.12A 2vn0A-3zu0A:
undetectable		 2vn0A-3zu0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 ASP A  94
HIS A 127
HIS A  46
 ZN  A1595 (-2.4A)
PO4  A1597 ( 4.0A)
ZN  A1596 (-3.3A)
 0.68A 2xxgA-3zu0A:
undetectable		 2xxgA-3zu0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 ASP A  94
HIS A 127
HIS A  46
 ZN  A1595 (-2.4A)
PO4  A1597 ( 4.0A)
ZN  A1596 (-3.3A)
 0.68A 2xxgC-3zu0A:
undetectable		 2xxgC-3zu0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.18A 2zj0A-3zu0A:
undetectable		 2zj0A-3zu0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 HIS A  91
GLU A 128
HIS A  45
GLY A 249
HIS A 227
 None
None
None
None
ZN  A1595 (-3.2A)
 1.25A 2zj0D-3zu0A:
undetectable		 2zj0D-3zu0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 ILE A  42
GLY A  93
GLY A 249
ASP A 250
MET A 114
 None
None
None
ZN  A1595 ( 3.2A)
None
 1.17A 2zw9A-3zu0A:
undetectable		 2zw9A-3zu0A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.20A 3ce6A-3zu0A:
undetectable		 3ce6A-3zu0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.24A 3ce6C-3zu0A:
undetectable		 3ce6C-3zu0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 GLY A 125
GLU A 128
ILE A  96
ALA A 131
THR A 184
 None
 1.17A 3ckkA-3zu0A:
undetectable		 3ckkA-3zu0A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 4 PRO A 491
TYR A 498
GLY A 493
THR A 429
 None
 1.41A 3ib0A-3zu0A:
undetectable		 3ib0A-3zu0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 11 ILE A 415
ILE A 385
PHE A 414
VAL A 445
GLY A 383
 None
 0.93A 3kw4A-3zu0A:
undetectable		 3kw4A-3zu0A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 THR A  99
ASP A 110
GLU A 128
 None
 0.52A 3qowA-3zu0A:
undetectable		 3qowA-3zu0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 GLY A 536
ARG A 437
GLY A 493
ALA A 416
ALA A 433
 None
A12  A1598 (-2.6A)
None
None
None
 1.09A 3sudA-3zu0A:
undetectable		 3sudA-3zu0A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 PHE A 453
ALA A 450
THR A 446
LEU A 100
 None
 1.21A 3t3zC-3zu0A:
undetectable		 3t3zC-3zu0A:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		9 / 9 ASN A 432
GLY A 434
GLY A 435
PHE A 456
ASN A 458
SER A 486
GLY A 488
TYR A 540
ASP A 546
 A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-3.6A)
A12  A1598 (-3.4A)
A12  A1598 (-3.1A)
A12  A1598 (-2.8A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 0.27A 3ztvA-3zu0A:
60.0		 3ztvA-3zu0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		8 / 9 GLY A 434
GLY A 435
PHE A 456
ASN A 538
SER A 486
GLY A 488
TYR A 540
ASP A 546
 A12  A1598 (-3.4A)
A12  A1598 (-3.6A)
A12  A1598 (-3.4A)
A12  A1598 ( 4.4A)
A12  A1598 (-2.8A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 1.04A 3ztvA-3zu0A:
60.0		 3ztvA-3zu0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 PRO A 399
PHE A 490
PRO A 491
LEU A 474
VAL A 514
 None
 1.30A 4a84A-3zu0A:
undetectable		 4a84A-3zu0A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 ASN A 233
GLU A 235
ILE A 236
ASN A 151
 None
 0.85A 4d33B-3zu0A:
undetectable		 4d33B-3zu0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 PHE A 200
ASN A 233
ILE A 246
GLY A 181
SER A 149
 None
 1.42A 4djfB-3zu0A:
2.5		 4djfB-3zu0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 PHE A 573
GLY A 383
ILE A 440
PHE A 453
 None
 0.89A 4ejjA-3zu0A:
undetectable		 4ejjA-3zu0A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 6 ASN A 233
TYR A 269
TYR A 255
LEU A 273
 None
 1.35A 4f8yA-3zu0A:
undetectable
4f8yB-3zu0A:
undetectable		 4f8yA-3zu0A:
15.45
4f8yB-3zu0A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 TYR A 269
TYR A 255
LEU A 273
ASN A 233
 None
 1.39A 4f8yC-3zu0A:
undetectable
4f8yD-3zu0A:
undetectable		 4f8yC-3zu0A:
15.45
4f8yD-3zu0A:
15.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		8 / 9 ARG A 397
ASN A 432
GLY A 434
GLY A 435
ARG A 437
PHE A 456
GLY A 488
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-3.6A)
A12  A1598 (-2.6A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 0.38A 4h2fA-3zu0A:
41.2		 4h2fA-3zu0A:
30.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 9 ASN A 432
GLY A 488
GLY A 434
ARG A 397
ASP A 546
 A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-3.0A)
A12  A1598 (-2.7A)
 1.41A 4h2fA-3zu0A:
41.2		 4h2fA-3zu0A:
30.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		8 / 9 ARG A 397
ASN A 432
GLY A 434
GLY A 435
ARG A 437
PHE A 456
GLY A 488
ASP A 546
 A12  A1598 (-3.0A)
A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-3.6A)
A12  A1598 (-2.6A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 0.45A 4h2gA-3zu0A:
41.3		 4h2gA-3zu0A:
30.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 9 ASN A 432
GLY A 434
ARG A 437
PHE A 456
ASP A 546
 A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-2.6A)
A12  A1598 (-3.4A)
A12  A1598 (-2.7A)
 1.14A 4h2gA-3zu0A:
41.3		 4h2gA-3zu0A:
30.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 9 ASN A 432
GLY A 488
GLY A 434
ARG A 397
ASP A 546
 A12  A1598 (-3.5A)
A12  A1598 (-3.4A)
A12  A1598 (-3.4A)
A12  A1598 (-3.0A)
A12  A1598 (-2.7A)
 1.41A 4h2gA-3zu0A:
41.3		 4h2gA-3zu0A:
30.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 1.06A 4kttA-3zu0A:
undetectable		 4kttA-3zu0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 0.99A 4kttC-3zu0A:
undetectable		 4kttC-3zu0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.24A 4lvcA-3zu0A:
undetectable		 4lvcA-3zu0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.22A 4lvcB-3zu0A:
undetectable		 4lvcB-3zu0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 1.03A 4ndnA-3zu0A:
undetectable		 4ndnA-3zu0A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 5 TYR A 540
GLY A 547
ASP A 476
VAL A 591
 A12  A1598 (-3.4A)
None
None
None
 1.00A 4nkvD-3zu0A:
undetectable		 4nkvD-3zu0A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LYS A 545
ALA A 131
GLY A 132
GLY A 106
PHE A 102
 None
 1.31A 4obwD-3zu0A:
undetectable		 4obwD-3zu0A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.25A 4pfjA-3zu0A:
undetectable		 4pfjA-3zu0A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.21A 4pgfA-3zu0A:
undetectable		 4pgfA-3zu0A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 11 TYR A 269
HIS A  46
HIS A 252
ASP A  94
GLY A  93
 None
ZN  A1596 (-3.3A)
ZN  A1596 ( 3.3A)
ZN  A1595 (-2.4A)
None
 1.36A 4qa0B-3zu0A:
undetectable		 4qa0B-3zu0A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 PHE A 200
SER A 192
GLU A 287
ASP A  44
 None
None
None
ZN  A1596 (-3.0A)
 1.31A 4qb9D-3zu0A:
undetectable		 4qb9D-3zu0A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 PHE A 119
LEU A 148
THR A 123
ASP A 183
GLY A  93
 None
 1.34A 4qb9E-3zu0A:
undetectable		 4qb9E-3zu0A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 LEU A 124
ASN A 133
LEU A 136
LEU A 140
 None
 0.68A 4wg0B-3zu0A:
undetectable
4wg0C-3zu0A:
undetectable		 4wg0B-3zu0A:
3.41
4wg0C-3zu0A:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 ASN A 133
LEU A 136
LEU A 140
LEU A 124
 None
 0.69A 4wg0L-3zu0A:
undetectable
4wg0M-3zu0A:
undetectable		 4wg0L-3zu0A:
3.41
4wg0M-3zu0A:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 0.98A 5a1iA-3zu0A:
undetectable		 5a1iA-3zu0A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASN A 126
PHE A 129
SER A 193
TYR A 540
 ZN  A1595 ( 2.7A)
None
A12  A1598 ( 4.7A)
A12  A1598 (-3.4A)
 1.02A 5amiB-3zu0A:
undetectable		 5amiB-3zu0A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.20A 5axaA-3zu0A:
undetectable		 5axaA-3zu0A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.21A 5axaC-3zu0A:
undetectable		 5axaC-3zu0A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 THR A  99
ASP A 110
GLU A 128
 None
 0.62A 5fa8A-3zu0A:
undetectable		 5fa8A-3zu0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 6 ILE A 440
GLY A 493
ASN A 590
ILE A 415
 None
 0.78A 5j4nB-3zu0A:
undetectable		 5j4nB-3zu0A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 GLU A 128
ASP A  44
GLY A 249
LEU A 182
ASN A 151
 None
ZN  A1596 (-3.0A)
None
None
None
 1.32A 5kbwA-3zu0A:
undetectable		 5kbwA-3zu0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 GLU A 128
ASP A  44
GLY A 249
LEU A 182
ASN A 151
 None
ZN  A1596 (-3.0A)
None
None
None
 1.31A 5kc4E-3zu0A:
undetectable		 5kc4E-3zu0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 ASP A 250
HIS A  46
ALA A  95
THR A 103
ARG A 437
 ZN  A1595 ( 3.2A)
ZN  A1596 (-3.3A)
None
None
A12  A1598 (-2.6A)
 1.47A 5m54B-3zu0A:
undetectable		 5m54B-3zu0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.17A 5m5kB-3zu0A:
undetectable		 5m5kB-3zu0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.21A 5m5kC-3zu0A:
undetectable		 5m5kC-3zu0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.21A 5m66B-3zu0A:
undetectable		 5m66B-3zu0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		3 / 3 SER A 149
ALA A 150
THR A 206
 None
 0.67A 5n0xB-3zu0A:
undetectable		 5n0xB-3zu0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 GLY A 249
ASP A 183
HIS A 127
ASP A  94
 None
None
PO4  A1597 ( 4.0A)
ZN  A1595 (-2.4A)
 0.87A 5nnwD-3zu0A:
undetectable		 5nnwD-3zu0A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 7 GLY A 249
ASP A 183
HIS A 127
ASP A  94
 None
None
PO4  A1597 ( 4.0A)
ZN  A1595 (-2.4A)
 0.83A 5no9D-3zu0A:
undetectable		 5no9D-3zu0A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 10 GLU A 287
GLY A 249
ALA A  92
HIS A  41
GLY A 288
 None
 1.08A 6e5zA-3zu0A:
undetectable		 6e5zA-3zu0A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 0.97A 6fbnB-3zu0A:
undetectable		 6fbnB-3zu0A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 0.99A 6fboA-3zu0A:
undetectable		 6fboA-3zu0A:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		4 / 8 ASP A 130
SER A 191
SER A 486
ASP A  94
 A12  A1598 ( 4.4A)
A12  A1598 (-3.8A)
A12  A1598 (-2.8A)
ZN  A1595 (-2.4A)
 1.01A 6fcbA-3zu0A:
undetectable		 6fcbA-3zu0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.22A 6gbnB-3zu0A:
undetectable		 6gbnB-3zu0A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 3zu0 NAD NUCLEOTIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 139
GLU A 128
ASP A  94
GLY A  98
HIS A  46
 None
None
ZN  A1595 (-2.4A)
None
ZN  A1596 (-3.3A)
 1.21A 6gbnD-3zu0A:
undetectable		 6gbnD-3zu0A:
22.98