SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zuc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		4 / 4 THR A  97
LEU A  38
VAL A  41
LEU A  43
 None
 1.08A 1fbmB-3zucA:
undetectable		 1fbmB-3zucA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		5 / 12 TYR A 118
GLY A  51
GLN A  55
GLN A  85
PHE A  47
 None
 1.40A 2akeA-3zucA:
undetectable		 2akeA-3zucA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		3 / 3 ALA A 130
THR A 134
PHE A 126
 None
 0.72A 2c6nB-3zucA:
undetectable		 2c6nB-3zucA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		5 / 12 ILE A 104
LEU A  28
LEU A   6
VAL A  41
PRO A  63
 None
 1.15A 3dcjA-3zucA:
undetectable
3dcjB-3zucA:
undetectable		 3dcjA-3zucA:
18.06
3dcjB-3zucA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		4 / 5 TYR A 118
ILE A  89
LEU A  87
PHE A  47
 None
 1.15A 3ls4L-3zucA:
undetectable		 3ls4L-3zucA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		4 / 4 LYS A  42
ALA A  90
SER A  92
THR A  70
 1PE  A1157 (-2.7A)
None
None
None
 1.31A 4i89B-3zucA:
undetectable		 4i89B-3zucA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3zuc CELLULOSOMAL
SCAFFOLDIN
(Acetivibrio
cellulolyticus) 		5 / 9 ALA A  90
ALA A  39
ALA A  94
SER A  93
GLY A  96
 None
 1.07A 6bklE-3zucA:
undetectable
6bklF-3zucA:
undetectable
6bklG-3zucA:
undetectable
6bklH-3zucA:
undetectable		 6bklE-3zucA:
6.54
6bklF-3zucA:
6.54
6bklG-3zucA:
6.54
6bklH-3zucA:
6.54