SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zuh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 142
ALA A 155
ILE A 158
ASP A 109
LEU A 174
 None
 0.95A 1tw4A-3zuhA:
undetectable		 1tw4A-3zuhA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 11 THR A  78
ALA A  84
GLY A  74
THR A  73
ALA A 175
 ADP  A1299 (-4.2A)
None
None
None
None
 1.19A 2f16H-3zuhA:
undetectable
2f16I-3zuhA:
undetectable		 2f16H-3zuhA:
20.98
2f16I-3zuhA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 11 THR A  78
ALA A  84
GLY A  74
THR A  73
ALA A 175
 ADP  A1299 (-4.2A)
None
None
None
None
 1.19A 2f16V-3zuhA:
undetectable
2f16W-3zuhA:
undetectable		 2f16V-3zuhA:
20.98
2f16W-3zuhA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		3 / 3 ARG A 144
ILE A 136
THR A  81
 None
None
ADP  A1299 (-2.4A)
 0.70A 3ia4D-3zuhA:
undetectable		 3ia4D-3zuhA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  29
LEU A  26
VAL A  25
VAL A  83
LEU A 102
 None
 1.31A 3m7rA-3zuhA:
undetectable		 3m7rA-3zuhA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 11 LEU A  90
LEU A  94
HIS A 197
PRO A  66
VAL A 171
 None
 1.29A 4mk4B-3zuhA:
undetectable		 4mk4B-3zuhA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_A_PARA500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 10 PHE A 135
THR A  78
ASP A 203
TYR A 177
GLY A  74
 None
ADP  A1299 (-4.2A)
None
None
None
 1.29A 4qb9A-3zuhA:
undetectable		 4qb9A-3zuhA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_C_PARC500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 10 PHE A 135
THR A  78
ASP A 203
TYR A 177
GLY A  74
 None
ADP  A1299 (-4.2A)
None
None
None
 1.30A 4qb9C-3zuhA:
undetectable		 4qb9C-3zuhA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3zuh PROTEIN CBBX
(Rhodobacter
sphaeroides) 		5 / 12 PHE A 135
THR A  78
ASP A 203
TYR A 177
GLY A  74
 None
ADP  A1299 (-4.2A)
None
None
None
 1.29A 4qb9E-3zuhA:
undetectable		 4qb9E-3zuhA:
22.58