SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		4 / 8 PHE A 147
ILE A 103
LEU A 155
VAL A 100
 None
 0.85A 1fslB-3zuyA:
undetectable		 1fslB-3zuyA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 VAL A 228
ASN A  93
LEU A  94
PRO A  95
ILE A  98
 None
 0.85A 1zq9B-3zuyA:
undetectable		 1zq9B-3zuyA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		4 / 6 MET A 169
ILE A  40
PRO A 109
SER A 139
 None
 1.38A 2qd3B-3zuyA:
undetectable		 2qd3B-3zuyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		4 / 7 GLY A 236
THR A  84
GLN A 264
PHE A 290
 None
None
NA  A1311 (-3.4A)
None
 1.15A 2qx4A-3zuyA:
undetectable
2qx4B-3zuyA:
undetectable		 2qx4A-3zuyA:
19.69
2qx4B-3zuyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 11 ALA A 274
ALA A 284
GLY A 212
GLY A  37
ILE A  40
 None
 0.88A 2x1lA-3zuyA:
undetectable		 2x1lA-3zuyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 ALA A 274
ALA A 284
GLY A 212
GLY A  37
ILE A  40
 None
 0.89A 2x1lB-3zuyA:
undetectable		 2x1lB-3zuyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		3 / 3 SER A 297
GLY A 234
GLY A 262
 None
PTY  A1319 (-3.5A)
NA  A1311 ( 4.7A)
 0.56A 3bogA-3zuyA:
undetectable
3bogC-3zuyA:
undetectable		 3bogA-3zuyA:
undetectable
3bogC-3zuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		4 / 4 SER A 297
GLY A 298
GLY A 234
GLY A 262
 None
None
PTY  A1319 (-3.5A)
NA  A1311 ( 4.7A)
 0.76A 3bogB-3zuyA:
undetectable
3bogD-3zuyA:
undetectable		 3bogB-3zuyA:
undetectable
3bogD-3zuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 GLY A 267
GLY A 111
GLY A 110
ILE A  40
ALA A 270
 None
None
NA  A1311 (-3.6A)
None
None
 0.90A 3douA-3zuyA:
undetectable		 3douA-3zuyA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		3 / 3 ASN A 124
ASN A 115
GLU A 260
 None
NA  A1310 (-3.3A)
NA  A1310 ( 2.6A)
 0.93A 3kpdC-3zuyA:
undetectable		 3kpdC-3zuyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 9 VAL A 131
ILE A  75
ALA A  76
ALA A 244
THR A 247
 None
 1.09A 3mdtA-3zuyA:
undetectable		 3mdtA-3zuyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 GLY A  73
ALA A 243
ALA A 244
THR A 258
LEU A 257
 None
None
None
PTY  A1319 (-4.0A)
None
 1.03A 3mteB-3zuyA:
undetectable		 3mteB-3zuyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 GLY A  73
ALA A 243
ALA A 244
THR A 258
LEU A 257
 None
None
None
PTY  A1319 (-4.0A)
None
 0.97A 3p2kA-3zuyA:
undetectable		 3p2kA-3zuyA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		3 / 3 GLY A 123
THR A 256
ASN A 124
 None
 0.71A 3v4tD-3zuyA:
undetectable		 3v4tD-3zuyA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		4 / 8 GLY A  45
GLY A  50
LEU A 195
VAL A 198
 LDA  A1316 ( 3.8A)
None
None
None
 0.92A 4fgzB-3zuyA:
undetectable		 4fgzB-3zuyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3zuy TRANSPORTER
(Neisseria
meningitidis) 		5 / 12 SER A 135
LEU A 257
THR A 256
ALA A 130
ASN A 115
 None
None
None
None
NA  A1310 (-3.3A)
 1.40A 5dsgB-3zuyA:
undetectable		 5dsgB-3zuyA:
24.57