SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3zv8 3C PROTEASE
(Enterovirus
D) 		4 / 4 HIS A  31
VAL A  30
THR A 180
LEU A 175
 None
 1.21A 1oq5A-3zv8A:
undetectable		 1oq5A-3zv8A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3zv8 3C PROTEASE
(Enterovirus
D) 		4 / 7 ILE A 158
ARG A  87
ILE A  86
PHE A   6
 None
 1.14A 2q6hA-3zv8A:
undetectable		 2q6hA-3zv8A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3zv8 3C PROTEASE
(Enterovirus
D) 		5 / 12 ILE A  72
GLY A 148
ILE A  37
VAL A 151
GLY A 159
 None
 0.88A 2qe6A-3zv8A:
undetectable		 2qe6A-3zv8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 3zv8 3C PROTEASE
(Enterovirus
D) 		5 / 11 ARG A 134
VAL A 116
PRO A 115
ILE A 135
ILE A 160
 None
 1.49A 3ganA-3zv8A:
undetectable		 3ganA-3zv8A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 3zv8 3C PROTEASE
(Enterovirus
D) 		5 / 12 ILE A 160
ILE A  10
PHE A  89
LEU A  90
THR A  26
 None
 1.09A 4cd2A-3zv8A:
undetectable		 4cd2A-3zv8A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3zv8 3C PROTEASE
(Enterovirus
D) 		4 / 5 LEU A  62
TYR A 178
ALA A 172
ILE A 160
 None
 1.18A 4y03B-3zv8A:
undetectable		 4y03B-3zv8A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3zv8 3C PROTEASE
(Enterovirus
D) 		5 / 12 LEU A 174
GLY A 148
ALA A 172
THR A  26
VAL A  17
 None
 1.27A 5x6yA-3zv8A:
undetectable		 5x6yA-3zv8A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3zv8 3C PROTEASE
(Enterovirus
D) 		5 / 11 VAL A 150
LEU A 174
ALA A   7
VAL A 119
TYR A 138
 None
 1.15A 6dryA-3zv8A:
undetectable		 6dryA-3zv8A:
18.20