SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA140_0
(LYSOZYME C)
3zvq LYSOZYME C
(Gallus
gallus)
3 / 3 ASN A  37
ALA A  42
ASN A  44
None
0.26A 1n4fA-3zvqA:
10.7
1n4fA-3zvqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)
3zvq LYSOZYME C
LYSOZYME C

(Gallus
gallus;
Gallus
gallus)
6 / 6 ASN A  65
ASP A  66
GLY A  67
THR A  69
PRO A  70
SER B  72
None
0.75A 1n4fA-3zvqA:
10.7
1n4fA-3zvqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3zvq LYSOZYME C
LYSOZYME C

(Gallus
gallus;
Gallus
gallus)
4 / 6 LEU B 129
GLY B 126
LEU A  25
SER A  24
None
0.90A 3aiaA-3zvqB:
undetectable
3aiaA-3zvqB:
14.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGA_A_ACTA1131_0
(LYSOZYME C)
3zvq LYSOZYME C
(Gallus
gallus)
3 / 3 ASN A  46
ASP A  52
ASN A  59
None
0.31A 4agaA-3zvqA:
10.6
4agaA-3zvqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)
3zvq LYSOZYME C
LYSOZYME C

(Gallus
gallus;
Gallus
gallus)
7 / 7 GLU A  35
ASP A  52
GLN A  57
ASN A  59
TRP A  63
ILE B  98
TRP B 108
None
0.24A 4ii8A-3zvqA:
10.6
4ii8A-3zvqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)
3zvq LYSOZYME C
LYSOZYME C

(Gallus
gallus;
Gallus
gallus)
5 / 5 GLU A  35
ASP A  52
TRP B 108
VAL B 109
ALA B 110
None
0.65A 5dl9A-3zvqA:
10.5
5dl9A-3zvqA:
100.00