SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 6 ARG A  50
PHE A  52
MET A  73
PHE A  71
 None
 1.47A 3af3A-3zvuA:
undetectable		 3af3A-3zvuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 7 GLU A  94
ILE A 110
HIS A  34
VAL A 139
 None
A8S  A 192 (-4.6A)
None
None
 0.93A 4a97A-3zvuA:
undetectable		 4a97A-3zvuA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 7 GLU A  94
ILE A 110
HIS A  34
VAL A 139
 None
A8S  A 192 (-4.6A)
None
None
 0.93A 4a97D-3zvuA:
undetectable		 4a97D-3zvuA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 7 GLU A  94
ILE A 110
HIS A  34
VAL A 139
 None
A8S  A 192 (-4.6A)
None
None
 0.90A 4a97H-3zvuA:
undetectable		 4a97H-3zvuA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 6 LEU A 166
TYR A  58
LYS A  59
PRO A  60
 None
None
A8S  A 192 (-2.5A)
None
 1.03A 4z4gA-3zvuA:
2.4		 4z4gA-3zvuA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3zvu ABSCISIC ACID
RECEPTOR PYR1
(Arabidopsis
thaliana) 		4 / 5 LEU A 140
VAL A 138
GLU A   9
LEU A   5
 None
 1.02A 5xooB-3zvuA:
undetectable		 5xooB-3zvuA:
18.52