SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zvz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 3zvz E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Homo
sapiens) 		4 / 7 CYH B 336
CYH B 363
HIS B 319
TRP B 358
 ZN  B 434 (-2.3A)
ZN  B 434 (-2.3A)
None
None
 1.50A 1yvmA-3zvzB:
undetectable		 1yvmA-3zvzB:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3zvz E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Homo
sapiens) 		4 / 6 HIS B 319
LEU B 320
CYH B 333
CYH B 336
 None
None
ZN  B 434 (-2.3A)
ZN  B 434 (-2.3A)
 1.38A 5hrqD-3zvzB:
undetectable
5hrqG-3zvzB:
undetectable
5hrqH-3zvzB:
undetectable		 5hrqD-3zvzB:
20.75
5hrqG-3zvzB:
18.18
5hrqH-3zvzB:
20.75