SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3zw5 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 7 PHE A  68
ASN A 138
ILE A 140
ASP A 134
 None
 0.96A 1yc2E-3zw5A:
undetectable		 1yc2E-3zw5A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3zw5 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 8 GLU A  96
GLU A 141
ASN A 144
SER A 129
 None
SO4  A1146 ( 4.9A)
None
None
 0.96A 4f93B-3zw5A:
undetectable		 4f93B-3zw5A:
6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3zw5 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 5 PHE A  68
TYR A  43
THR A  32
ILE A  29
 None
 1.21A 4jx1E-3zw5A:
undetectable		 4jx1E-3zw5A:
14.94