SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		3 / 3 TRP A 109
LEU A 106
LYS A  85
 None
 1.42A 1yajK-3zw6A:
undetectable		 1yajK-3zw6A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		4 / 5 LEU A  97
PRO A 103
VAL A 102
ILE A 100
 None
 0.84A 2aoiB-3zw6A:
undetectable		 2aoiB-3zw6A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		5 / 12 VAL A 227
VAL A 195
LEU A 199
GLY A 137
LEU A 175
 None
 0.95A 3n8wA-3zw6A:
undetectable		 3n8wA-3zw6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		5 / 11 GLY A 128
PRO A 224
ILE A 226
LEU A  86
ILE A  90
 None
 1.10A 4dt8A-3zw6A:
undetectable		 4dt8A-3zw6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		5 / 10 GLY A 128
PRO A 224
ILE A 226
LEU A  86
ILE A  90
 None
 0.90A 4dt8B-3zw6A:
undetectable		 4dt8B-3zw6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		4 / 5 ARG A 266
THR A 267
ASP A 268
TYR A 298
 None
 1.46A 4oltA-3zw6A:
undetectable		 4oltA-3zw6A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		4 / 5 ARG A 266
THR A 267
ASP A 268
TYR A 298
 None
 1.46A 4qwpB-3zw6A:
2.5		 4qwpB-3zw6A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		5 / 12 VAL A 227
VAL A 195
GLY A 137
ALA A 136
LEU A 175
 None
 1.13A 5iktA-3zw6A:
undetectable		 5iktA-3zw6A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3zw6 RIBULOSE
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E ACTIVASE 1,
CHLOROPLASTIC
(Nicotiana
tabacum) 		4 / 8 ASN A 130
PRO A 131
GLU A 121
PHE A 124
 None
 1.48A 5oh1C-3zw6A:
undetectable		 5oh1C-3zw6A:
19.22