SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		3 / 3 PHE A 364
LEU A 213
SER A 416
 None
 0.85A 1e7aA-3zx2A:
undetectable		 1e7aA-3zx2A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 THR A  98
ALA A 151
LEU A 128
MET A 134
ILE A 168
 None
None
None
CL  A 503 ( 4.9A)
None
 1.17A 1errA-3zx2A:
undetectable		 1errA-3zx2A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 7 SER A 340
SER A 235
ALA A 231
PHE A 348
 CL  A 506 ( 4.1A)
None
None
None
 1.09A 1fxvA-3zx2A:
undetectable
1fxvB-3zx2A:
undetectable		 1fxvA-3zx2A:
18.14
1fxvB-3zx2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 8 SER A 340
SER A 235
ALA A 231
PHE A 348
 CL  A 506 ( 4.1A)
None
None
None
 1.02A 1gm7A-3zx2A:
undetectable
1gm7B-3zx2A:
undetectable		 1gm7A-3zx2A:
18.14
1gm7B-3zx2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 10 GLY A 357
HIS A 439
ALA A 449
ASN A 183
ILE A 444
 None
 0.87A 1likA-3zx2A:
undetectable		 1likA-3zx2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		3 / 3 PHE A 430
LEU A 211
MET A 441
 None
 0.66A 1mx1D-3zx2A:
undetectable		 1mx1D-3zx2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 GLY A  56
ALA A  55
ASP A  54
VAL A 148
ILE A  91
 None
 1.11A 1sduB-3zx2A:
undetectable		 1sduB-3zx2A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 LEU A 105
TYR A 104
ILE A 101
GLY A  56
 None
 0.93A 2du8A-3zx2A:
undetectable		 2du8A-3zx2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 LEU A 105
TYR A 104
ILE A 101
GLY A  56
 None
 0.95A 2du8B-3zx2A:
undetectable		 2du8B-3zx2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 10 THR A  60
ALA A 130
THR A 131
ALA A 132
GLY A  90
 None
None
None
CL  A 501 ( 4.1A)
CL  A 503 ( 3.8A)
 1.04A 2f16K-3zx2A:
undetectable
2f16L-3zx2A:
undetectable		 2f16K-3zx2A:
16.59
2f16L-3zx2A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 10 THR A  60
ALA A 130
THR A 131
ALA A 132
GLY A  90
 None
None
None
CL  A 501 ( 4.1A)
CL  A 503 ( 3.8A)
 1.04A 2f16Y-3zx2A:
undetectable
2f16Z-3zx2A:
undetectable		 2f16Y-3zx2A:
16.59
2f16Z-3zx2A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 LYS A 378
LEU A 421
ILE A 420
GLY A 427
LEU A 352
 None
ACY  A 511 (-4.4A)
ACY  A 511 ( 3.9A)
None
None
 1.31A 2lbdA-3zx2A:
undetectable		 2lbdA-3zx2A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 5 TYR A 104
ILE A 101
LEU A 156
LEU A 128
 None
 1.14A 2zb7A-3zx2A:
undetectable		 2zb7A-3zx2A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 4 SER A  57
GLY A 133
GLY A 214
GLY A 256
 CL  A 502 ( 3.2A)
CL  A 503 ( 3.7A)
CL  A 501 (-3.6A)
None
 0.89A 3bogB-3zx2A:
undetectable
3bogD-3zx2A:
undetectable		 3bogB-3zx2A:
undetectable
3bogD-3zx2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 GLU A 174
GLY A 175
GLY A 214
SER A 217
PHE A 252
 None
None
CL  A 501 (-3.6A)
CL  A 501 (-4.2A)
None
 1.06A 3k13C-3zx2A:
undetectable		 3k13C-3zx2A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 ASP A 268
LEU A 261
PHE A 415
ILE A 328
SER A 327
 None
 1.49A 3o94A-3zx2A:
undetectable		 3o94A-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 LEU A 261
ASP A 279
PHE A 415
ILE A 328
SER A 327
 None
 1.44A 3o94A-3zx2A:
undetectable		 3o94A-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 ASP A 268
LEU A 261
PHE A 415
ILE A 328
SER A 327
 None
 1.46A 3o94B-3zx2A:
undetectable		 3o94B-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 LEU A 261
ASP A 279
PHE A 415
ILE A 328
SER A 327
 None
 1.42A 3o94B-3zx2A:
undetectable		 3o94B-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 ASP A 268
LEU A 261
PHE A 415
ILE A 328
SER A 327
 None
 1.47A 3o94C-3zx2A:
undetectable		 3o94C-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 LEU A 261
ASP A 279
PHE A 415
ILE A 328
SER A 327
 None
 1.43A 3o94C-3zx2A:
undetectable		 3o94C-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 ASP A 268
LEU A 261
PHE A 415
ILE A 328
SER A 327
 None
 1.48A 3o94D-3zx2A:
undetectable		 3o94D-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 11 LEU A 261
ASP A 279
PHE A 415
ILE A 328
SER A 327
 None
 1.43A 3o94D-3zx2A:
undetectable		 3o94D-3zx2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 4 LEU A  53
ILE A 116
TYR A  65
TYR A 159
 None
 1.32A 3vt7A-3zx2A:
undetectable		 3vt7A-3zx2A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 THR A 221
GLY A 209
ILE A 182
LEU A 211
 None
 1.24A 4acaC-3zx2A:
3.2		 4acaC-3zx2A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 PHE A 364
ASP A 212
GLY A  56
SER A  58
GLN A  85
 None
 0.91A 4djeA-3zx2A:
undetectable		 4djeA-3zx2A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 PHE A 364
ASP A 212
GLY A  56
SER A  58
GLN A  85
 None
 1.11A 4djeB-3zx2A:
undetectable		 4djeB-3zx2A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 PHE A 364
ASP A 212
GLY A  56
SER A  58
GLN A  85
 None
 1.35A 4djfB-3zx2A:
undetectable		 4djfB-3zx2A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 8 SER A 251
GLN A 219
ILE A 420
VAL A 365
 None
None
ACY  A 511 ( 3.9A)
None
 0.66A 4dx7B-3zx2A:
undetectable		 4dx7B-3zx2A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		6 / 12 PHE A 362
TYR A 419
GLY A 427
LEU A 424
SER A 422
ILE A 220
 None
 1.43A 4krhA-3zx2A:
undetectable		 4krhA-3zx2A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 7 PHE A 222
ILE A 220
PHE A 430
ASN A 429
 None
 1.28A 4o7gA-3zx2A:
undetectable
4o7gB-3zx2A:
undetectable		 4o7gA-3zx2A:
19.00
4o7gB-3zx2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 ILE A 331
TYR A 419
PHE A 344
ASN A 334
 None
 1.17A 4o7gB-3zx2A:
undetectable		 4o7gB-3zx2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 PHE A 222
ILE A 220
PHE A 430
ASN A 429
 None
 1.29A 4o7gB-3zx2A:
undetectable		 4o7gB-3zx2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 5 ALA A  95
THR A  98
VAL A 152
ILE A 101
 None
 0.95A 4xe3A-3zx2A:
undetectable		 4xe3A-3zx2A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 5 ALA A  95
THR A  98
VAL A 152
ILE A 101
 None
 0.93A 4xe3B-3zx2A:
undetectable		 4xe3B-3zx2A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 10 GLY A 214
GLY A 215
ARG A 135
GLY A  56
SER A  57
 CL  A 501 (-3.6A)
CL  A 502 ( 4.0A)
None
None
CL  A 502 ( 3.2A)
 1.01A 5aqyA-3zx2A:
4.0		 5aqyA-3zx2A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		4 / 6 ILE A 438
LEU A 424
PHE A 430
THR A 221
 None
 1.01A 5b1aN-3zx2A:
undetectable
5b1aW-3zx2A:
undetectable		 5b1aN-3zx2A:
21.66
5b1aW-3zx2A:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 PHE A 440
ILE A 438
LEU A 211
GLY A 417
LEU A 213
 None
None
None
ACY  A 511 (-3.4A)
None
 1.17A 5zwrA-3zx2A:
undetectable		 5zwrA-3zx2A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1
(Rattus
norvegicus) 		5 / 12 GLY A  56
ALA A  55
ASP A  54
VAL A 148
ILE A  91
 None
 0.94A 6dgxA-3zx2A:
undetectable		 6dgxA-3zx2A:
11.81