SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 3zxu MCM21
(Kluyveromyces
lactis) 		5 / 11 LEU A 124
VAL A 155
ILE A 180
ILE A 187
ILE A 137
 None
 0.94A 1c6yA-3zxuA:
undetectable		 1c6yA-3zxuA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3zxu MCM21
(Kluyveromyces
lactis) 		5 / 9 LEU A 124
VAL A 155
ILE A 180
ILE A 187
ILE A 137
 None
 0.92A 1hpvA-3zxuA:
undetectable		 1hpvA-3zxuA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3zxu MCM21
(Kluyveromyces
lactis) 		4 / 6 ILE A 187
CYH A 205
LEU A 124
ILE A 137
 None
 1.03A 2q83B-3zxuA:
undetectable		 2q83B-3zxuA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3zxu CTF19
(Kluyveromyces
lactis) 		5 / 11 LEU B 132
LEU B 158
MET B 154
ALA B 181
VAL B 185
 None
 1.10A 3e22B-3zxuB:
undetectable		 3e22B-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3zxu CTF19
(Kluyveromyces
lactis) 		5 / 11 LEU B 133
LEU B 158
ALA B 140
MET B 154
ALA B 172
 None
 1.26A 3e22B-3zxuB:
undetectable		 3e22B-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3zxu CTF19
(Kluyveromyces
lactis) 		5 / 11 LEU B 132
LEU B 158
MET B 154
ALA B 181
VAL B 185
 None
 1.08A 3e22D-3zxuB:
undetectable		 3e22D-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3zxu CTF19
(Kluyveromyces
lactis) 		5 / 11 LEU B 133
LEU B 158
ALA B 140
MET B 154
ALA B 172
 None
 1.27A 3e22D-3zxuB:
undetectable		 3e22D-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 3zxu MCM21
CTF19
(Kluyveromyces
lactis;
Kluyveromyces
lactis) 		4 / 6 GLU A 144
THR B 175
GLN A 217
LEU A 210
 None
 1.41A 4qzuC-3zxuA:
undetectable		 4qzuC-3zxuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 3zxu MCM21
(Kluyveromyces
lactis) 		5 / 9 LEU A 124
VAL A 155
ILE A 180
ILE A 187
ILE A 137
 None
 0.86A 5kqxB-3zxuA:
undetectable		 5kqxB-3zxuA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 3zxu MCM21
CTF19
(Kluyveromyces
lactis;
Kluyveromyces
lactis) 		5 / 10 LEU A 139
ILE A 180
LEU A 169
LEU B  80
GLU A 140
 None
 1.15A 5y7pG-3zxuA:
undetectable		 5y7pG-3zxuA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3zxu CTF19
MCM21
(Kluyveromyces
lactis) 		5 / 12 VAL A 127
LEU B  77
GLU A 133
GLY A 136
LEU B  81
 None
 1.13A 6f6iA-3zxuA:
undetectable
6f6iB-3zxuA:
undetectable		 6f6iA-3zxuA:
13.38
6f6iB-3zxuA:
14.59