SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OTH_A_IMNA301_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	3zys	DYNAMIN-1 (Homo sapiens)	3 / 3	ASP C 91 TYR C 89 LYS C 54	None	1.21A	2othA-3zysC: undetectable	2othA-3zysC: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B0W_A_DGXA1_2 (NUCLEAR RECEPTOR ROR-GAMMA)	3zys	DYNAMIN-1 (Homo sapiens)	3 / 3	TRP C 108 VAL C 88 ARG C 86	None	0.69A	3b0wA-3zysC: undetectable	3b0wA-3zysC: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC552_1 (GLUTAMATE DEHYDROGENASE)	3zys	DYNAMIN-1 (Homo sapiens)	3 / 3	TYR C 92 TYR C 33 GLY C 24	None	0.75A	3eteB-3zysC: undetectable 3eteD-3zysC: undetectable 3eteF-3zysC: undetectable	3eteB-3zysC: 12.86 3eteD-3zysC: 12.86 3eteF-3zysC: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4H_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	3zys	DYNAMIN-1 (Homo sapiens)	4 / 5	TYR C 92 LYS C 90 LEU C 57 TYR C 55	None	1.21A	4z4hA-3zysC: undetectable	4z4hA-3zysC: 9.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OTH_A_IMNA301_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","3zys","DYNAMIN-1","Homo sapiens",3,"ASP C  91;TYR C  89;LYS C  54","None","1.21A","2othA-3zysC:undetectable","2othA-3zysC:20.47"],["3B0W_A_DGXA1_2","NUCLEAR RECEPTOR ROR-GAMMA","3zys","DYNAMIN-1","Homo sapiens",3,"TRP C 108;VAL C  88;ARG C  86","None","0.69A","3b0wA-3zysC:undetectable","3b0wA-3zysC:20.68"],["3ETE_C_H3PC552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","3zys","DYNAMIN-1","Homo sapiens",3,"TYR C  92;TYR C  33;GLY C  24","None","0.75A","3eteB-3zysC:undetectable;3eteD-3zysC:undetectable;3eteF-3zysC:undetectable","3eteB-3zysC:12.86;3eteD-3zysC:12.86;3eteF-3zysC:12.86"],["4Z4H_A_IPHA902_0","PROTEIN ARGONAUTE-2","3zys","DYNAMIN-1","Homo sapiens",4,"TYR C  92;LYS C  90;LEU C  57;TYR C  55","None","1.21A","4z4hA-3zysC:undetectable","4z4hA-3zysC:9.04"]]