SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zyt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_2
(MINERALOCORTICOID
RECEPTOR)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 4 LEU A 187
LEU A  67
MET A 157
CYH A  60
 None
 1.50A 2oaxC-3zytA:
0.0		 2oaxC-3zytA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 LEU A 219
TYR A 148
GLY A 113
LEU A 118
ALA A 245
 None
 1.33A 3ou7C-3zytA:
undetectable		 3ou7C-3zytA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		3 / 3 SER A 316
PHE A 320
LYS A 307
 None
 0.92A 3u88A-3zytA:
undetectable		 3u88A-3zytA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.35A 3wg7A-3zytA:
0.4
3wg7B-3zytA:
undetectable
3wg7T-3zytA:
undetectable		 3wg7A-3zytA:
20.15
3wg7B-3zytA:
20.27
3wg7T-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.33A 3x2qA-3zytA:
undetectable
3x2qB-3zytA:
undetectable
3x2qT-3zytA:
undetectable		 3x2qA-3zytA:
20.15
3x2qB-3zytA:
20.27
3x2qT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 8 SER A 244
SER A 243
GLY A 188
GLN A 170
 None
 0.93A 4af0A-3zytA:
undetectable		 4af0A-3zytA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 6 GLY A  92
TRP A  88
GLU A 159
ARG A 163
 None
 1.30A 4bqfA-3zytA:
undetectable		 4bqfA-3zytA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 8 LEU A 359
TYR A 342
VAL A  13
LEU A  21
 None
 1.00A 4l1xA-3zytA:
undetectable		 4l1xA-3zytA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 10 VAL A 283
GLY A  63
PHE A 305
SER A 106
GLY A 302
 None
 1.23A 4mmdA-3zytA:
undetectable		 4mmdA-3zytA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 7 HIS A  48
PRO A  47
SER A 326
ASP A  26
 None
 1.32A 4odjA-3zytA:
undetectable		 4odjA-3zytA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 6 LEU A 242
ASN A 124
MET A 157
LEU A 187
 None
 1.08A 4okxA-3zytA:
undetectable		 4okxA-3zytA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 SER A 316
GLY A 315
ALA A 255
GLY A 330
PHE A 331
 None
 1.28A 4r29A-3zytA:
undetectable		 4r29A-3zytA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 GLY A 247
ALA A 255
MET A 254
GLY A 253
PHE A 185
 None
 1.25A 4r29B-3zytA:
undetectable		 4r29B-3zytA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 GLY A 247
ALA A 255
MET A 254
GLY A 253
PHE A 185
 None
 1.26A 4r29C-3zytA:
undetectable		 4r29C-3zytA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 SER A 316
GLY A 315
ALA A 255
GLY A 330
PHE A 331
 None
 1.28A 4r29C-3zytA:
undetectable		 4r29C-3zytA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 9 LEU A 265
GLU A 252
ILE A 177
MET A  64
THR A 181
 None
 1.31A 4x3mA-3zytA:
undetectable		 4x3mA-3zytA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 5 ALA A 362
HIS A 322
PRO A 313
PHE A 331
 None
 1.42A 4ze2A-3zytA:
undetectable		 4ze2A-3zytA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.39A 5b1aA-3zytA:
undetectable
5b1aB-3zytA:
undetectable
5b1aT-3zytA:
undetectable		 5b1aA-3zytA:
20.15
5b1aB-3zytA:
20.27
5b1aT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.41A 5b1bA-3zytA:
undetectable
5b1bB-3zytA:
undetectable
5b1bT-3zytA:
undetectable		 5b1bA-3zytA:
20.15
5b1bB-3zytA:
20.27
5b1bT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.40A 5b3sA-3zytA:
undetectable
5b3sB-3zytA:
undetectable
5b3sT-3zytA:
undetectable		 5b3sA-3zytA:
20.15
5b3sB-3zytA:
20.27
5b3sT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 6 ARG A  36
GLY A  37
THR A 263
GLU A 337
 None
 0.94A 5ny7A-3zytA:
undetectable		 5ny7A-3zytA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 ALA A 372
PHE A  10
ALA A 255
ALA A 259
THR A 263
 None
 1.03A 5tl8A-3zytA:
undetectable		 5tl8A-3zytA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 5 ASP A 333
PRO A 273
ARG A  36
THR A 263
 None
 1.45A 5uxcA-3zytA:
undetectable		 5uxcA-3zytA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.40A 5x19A-3zytA:
undetectable
5x19B-3zytA:
undetectable
5x19T-3zytA:
undetectable		 5x19A-3zytA:
20.15
5x19B-3zytA:
20.27
5x19T-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.42A 5xdxA-3zytA:
0.0
5xdxB-3zytA:
undetectable
5xdxT-3zytA:
undetectable		 5xdxA-3zytA:
20.15
5xdxB-3zytA:
20.27
5xdxT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.40A 5z84A-3zytA:
undetectable
5z84B-3zytA:
undetectable
5z84T-3zytA:
undetectable		 5z84A-3zytA:
20.15
5z84B-3zytA:
20.27
5z84T-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.40A 5z86A-3zytA:
undetectable
5z86B-3zytA:
undetectable
5z86T-3zytA:
undetectable		 5z86A-3zytA:
20.15
5z86B-3zytA:
20.27
5z86T-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.36A 5zcoA-3zytA:
undetectable
5zcoB-3zytA:
undetectable
5zcoT-3zytA:
undetectable		 5zcoA-3zytA:
20.15
5zcoB-3zytA:
20.27
5zcoT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.40A 5zcpA-3zytA:
undetectable
5zcpB-3zytA:
undetectable
5zcpT-3zytA:
undetectable		 5zcpA-3zytA:
20.15
5zcpB-3zytA:
20.27
5zcpT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 11 GLY A 154
GLN A 170
GLU A 158
THR A 168
GLY A  66
 None
 1.41A 5zcqA-3zytA:
undetectable
5zcqB-3zytA:
undetectable
5zcqT-3zytA:
undetectable		 5zcqA-3zytA:
20.15
5zcqB-3zytA:
20.27
5zcqT-3zytA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 LYS A  62
TYR A 148
GLY A 324
ALA A 325
LEU A 229
 None
 1.11A 5zwrA-3zytA:
31.0		 5zwrA-3zytA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 SER A  59
LYS A  62
TYR A 148
ALA A 325
LEU A 229
 None
 1.10A 5zwrB-3zytA:
30.9		 5zwrB-3zytA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 SER A  59
LYS A  62
TYR A 148
PHE A 295
ALA A 325
 None
 1.31A 5zwrB-3zytA:
30.9		 5zwrB-3zytA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 SER A  59
TYR A 148
ILE A 153
ALA A 245
LEU A 242
 None
 1.25A 5zwrB-3zytA:
30.9		 5zwrB-3zytA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		5 / 12 ALA A 372
PHE A  10
ALA A 255
ALA A 259
THR A 263
 None
 1.01A 6aycA-3zytA:
undetectable		 6aycA-3zytA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_1
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3zyt ESTERASE A
(Paenarthrobacter
nitroguajacolicu
s) 		4 / 4 ASP A 323
ALA A 319
SER A 308
PHE A 301
 None
 1.27A 6cm4A-3zytA:
0.0		 6cm4A-3zytA:
21.30