SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.50A 1c9sL-3zyvA:
undetectable
1c9sM-3zyvA:
undetectable		 1c9sL-3zyvA:
4.62
1c9sM-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.50A 1c9sO-3zyvA:
undetectable
1c9sP-3zyvA:
undetectable		 1c9sO-3zyvA:
4.62
1c9sP-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ILE A 831
ARG A 829
TYR A 679
PHE A 611
 None
 1.08A 1e71M-3zyvA:
undetectable		 1e71M-3zyvA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ILE A 831
ARG A 829
TYR A 679
PHE A 611
 None
 1.10A 1e72M-3zyvA:
undetectable		 1e72M-3zyvA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3zyv AOX3
(Mus
musculus) 		4 / 6 ILE A 831
ARG A 829
TYR A 679
PHE A 611
 None
 1.08A 1e73M-3zyvA:
undetectable		 1e73M-3zyvA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.49A 1gtfO-3zyvA:
undetectable
1gtfP-3zyvA:
undetectable		 1gtfO-3zyvA:
4.62
1gtfP-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		4 / 6 THR A1269
LEU A1210
GLY A1209
TYR A1211
 None
 1.32A 1gtiC-3zyvA:
undetectable		 1gtiC-3zyvA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.44A 1gtnR-3zyvA:
undetectable
1gtnS-3zyvA:
undetectable		 1gtnR-3zyvA:
4.62
1gtnS-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.48A 1gtnS-3zyvA:
undetectable
1gtnT-3zyvA:
undetectable		 1gtnS-3zyvA:
4.62
1gtnT-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		5 / 11 GLY A1044
GLY A1046
GLU A1042
ARG A 798
GLY A 800
 MTE  A3003 (-3.8A)
None
None
None
None
 0.97A 1jg3A-3zyvA:
undetectable		 1jg3A-3zyvA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		5 / 11 GLY A1044
GLY A1046
GLU A1042
ARG A 798
GLY A 800
 MTE  A3003 (-3.8A)
None
None
None
None
 0.94A 1jg3B-3zyvA:
undetectable		 1jg3B-3zyvA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3zyv AOX3
(Mus
musculus) 		4 / 7 PRO A1156
ALA A1143
TYR A1020
SER A1011
 None
 1.06A 1k5qA-3zyvA:
undetectable
1k5qB-3zyvA:
undetectable		 1k5qA-3zyvA:
9.16
1k5qB-3zyvA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 3zyv AOX3
(Mus
musculus) 		4 / 4 ASP A1182
HIS A1245
ARG A1180
GLU A1243
 None
 1.30A 1lqtA-3zyvA:
undetectable		 1lqtA-3zyvA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 3zyv AOX3
(Mus
musculus) 		4 / 5 SER A1247
ASN A 979
ALA A 975
ASP A1182
 None
 1.42A 1lqtA-3zyvA:
undetectable
1lqtB-3zyvA:
undetectable		 1lqtA-3zyvA:
17.22
1lqtB-3zyvA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 3zyv AOX3
(Mus
musculus) 		4 / 5 SER A1247
ASN A 979
ALA A 975
ASP A1182
 None
 1.42A 1lquA-3zyvA:
undetectable
1lquB-3zyvA:
undetectable		 1lquA-3zyvA:
17.22
1lquB-3zyvA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A  53
GLN A 348
MET A 124
CYH A 152
ILE A1234
 FES  A3002 (-3.9A)
None
None
FES  A3001 (-2.2A)
None
 1.37A 1m2zD-3zyvA:
undetectable		 1m2zD-3zyvA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ALA A 706
LEU A 707
ARG A 904
PHE A 919
ILE A 713
 None
 1.23A 1mx8A-3zyvA:
undetectable		 1mx8A-3zyvA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ILE A1307
ALA A1310
VAL A1283
ARG A1287
ALA A1278
 None
 1.20A 1n4hA-3zyvA:
undetectable		 1n4hA-3zyvA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3zyv AOX3
(Mus
musculus) 		5 / 10 GLY A1083
PHE A 919
GLU A1266
GLY A1013
THR A1081
 MTE  A3003 (-3.6A)
None
MOS  A3004 (-4.3A)
None
None
 1.32A 1pwyE-3zyvA:
undetectable		 1pwyE-3zyvA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 VAL A 352
ALA A 353
HIS A 358
 None
FAD  A3005 (-3.6A)
FAD  A3005 (-3.8A)
 0.62A 1q23C-3zyvA:
undetectable		 1q23C-3zyvA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 VAL A 352
ALA A 353
HIS A 358
 None
FAD  A3005 (-3.6A)
FAD  A3005 (-3.8A)
 0.74A 1q23H-3zyvA:
undetectable		 1q23H-3zyvA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 VAL A 352
ALA A 353
HIS A 358
 None
FAD  A3005 (-3.6A)
FAD  A3005 (-3.8A)
 0.76A 1q23G-3zyvA:
undetectable		 1q23G-3zyvA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 VAL A 352
ALA A 353
HIS A 358
 None
FAD  A3005 (-3.6A)
FAD  A3005 (-3.8A)
 0.55A 1q23L-3zyvA:
undetectable		 1q23L-3zyvA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ASN A 369
LEU A 392
SER A 361
ILE A 360
LEU A 405
 None
None
FAD  A3005 ( 4.6A)
FAD  A3005 (-3.8A)
None
 1.05A 1rg7A-3zyvA:
undetectable		 1rg7A-3zyvA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 PRO A 219
GLY A  86
ALA A  88
PRO A  64
ALA A 226
 None
 1.04A 1sg9C-3zyvA:
undetectable		 1sg9C-3zyvA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 GLN A1027
ILE A1028
TYR A1029
 None
 0.62A 1vifA-3zyvA:
undetectable		 1vifA-3zyvA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		5 / 11 GLU A 145
GLY A 149
GLY A 346
ILE A 143
LEU A 131
 None
 0.82A 1x7pA-3zyvA:
undetectable
1x7pB-3zyvA:
undetectable		 1x7pA-3zyvA:
12.59
1x7pB-3zyvA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 333
ALA A 336
GLN A 340
LEU A 368
ALA A 427
 None
 0.69A 1xiuB-3zyvA:
undetectable		 1xiuB-3zyvA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3zyv AOX3
(Mus
musculus) 		3 / 3 PHE A1160
ARG A 947
ASN A 892
 None
 0.75A 1xzxX-3zyvA:
undetectable		 1xzxX-3zyvA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3zyv AOX3
(Mus
musculus) 		4 / 5 ILE A 584
ILE A1258
ILE A1052
MET A1063
 None
 0.78A 1zgyA-3zyvA:
undetectable		 1zgyA-3zyvA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ILE A 333
ALA A 336
GLN A 340
LEU A 368
ALA A 427
 None
 0.54A 2aclE-3zyvA:
undetectable		 2aclE-3zyvA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 333
ALA A 336
GLN A 340
LEU A 368
ALA A 427
 None
 0.65A 2aclG-3zyvA:
undetectable		 2aclG-3zyvA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3zyv AOX3
(Mus
musculus) 		4 / 7 GLY A 920
SER A 879
PHE A 919
GLU A 880
 None
NA  A2337 (-2.4A)
None
None
 1.05A 2c8aD-3zyvA:
undetectable		 2c8aD-3zyvA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 3zyv AOX3
(Mus
musculus) 		3 / 3 PHE A 526
VAL A 530
TRP A 485
 None
 0.90A 2cc8A-3zyvA:
undetectable		 2cc8A-3zyvA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3zyv AOX3
(Mus
musculus) 		3 / 3 PHE A 526
VAL A 530
TRP A 485
 None
 0.89A 2ccbA-3zyvA:
undetectable		 2ccbA-3zyvA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ARG A 917
PHE A 803
GLY A 805
GLY A1083
GLN A1045
 MTE  A3003 ( 2.9A)
MTE  A3003 (-4.1A)
None
MTE  A3003 (-3.6A)
MTE  A3003 (-4.1A)
 1.30A 2eikG-3zyvA:
undetectable
2eikN-3zyvA:
undetectable
2eikO-3zyvA:
undetectable		 2eikG-3zyvA:
4.98
2eikN-3zyvA:
18.19
2eikO-3zyvA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3zyv AOX3
(Mus
musculus) 		4 / 8 ARG A 829
GLU A 609
VAL A 769
TYR A 768
 None
 1.14A 2fl5E-3zyvA:
undetectable
2fl5F-3zyvA:
undetectable		 2fl5E-3zyvA:
9.56
2fl5F-3zyvA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ILE A  95
GLY A  42
THR A  43
GLU A  93
GLY A  94
 None
 1.20A 2fn1A-3zyvA:
undetectable		 2fn1A-3zyvA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 828
GLY A 608
ALA A 676
ALA A 675
VAL A 674
 None
 0.92A 2oc8A-3zyvA:
undetectable		 2oc8A-3zyvA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3zyv AOX3
(Mus
musculus) 		3 / 3 PHE A 526
VAL A 530
TRP A 485
 None
 0.89A 2vx9A-3zyvA:
undetectable		 2vx9A-3zyvA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3zyv AOX3
(Mus
musculus) 		5 / 12 THR A 269
VAL A 352
SER A  73
SER A 127
GLY A  50
 FAD  A3005 (-3.0A)
None
None
None
FES  A3002 ( 3.1A)
 1.16A 2x2iA-3zyvA:
undetectable		 2x2iA-3zyvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3zyv AOX3
(Mus
musculus) 		5 / 12 THR A 269
VAL A 352
SER A  73
SER A 127
GLY A  50
 FAD  A3005 (-3.0A)
None
None
None
FES  A3002 ( 3.1A)
 1.24A 2x2iC-3zyvA:
undetectable		 2x2iC-3zyvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3zyv AOX3
(Mus
musculus) 		5 / 10 THR A 269
VAL A 352
SER A  73
SER A 127
GLY A  50
 FAD  A3005 (-3.0A)
None
None
None
FES  A3002 ( 3.1A)
 1.25A 2x2iD-3zyvA:
undetectable		 2x2iD-3zyvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLN A 923
PHE A 919
GLY A 920
GLY A 805
 None
 0.69A 2y6rB-3zyvA:
undetectable		 2y6rB-3zyvA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3zyv AOX3
(Mus
musculus) 		3 / 3 TYR A 659
VAL A 819
THR A 643
 None
 0.73A 2ygnA-3zyvA:
undetectable		 2ygnA-3zyvA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3zyv AOX3
(Mus
musculus) 		4 / 6 GLU A1168
ALA A1281
ASN A 993
ALA A1282
 None
 1.19A 2zgwB-3zyvA:
undetectable		 2zgwB-3zyvA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ARG A 917
PHE A 803
GLY A 805
GLY A1083
GLN A1045
 MTE  A3003 ( 2.9A)
MTE  A3003 (-4.1A)
None
MTE  A3003 (-3.6A)
MTE  A3003 (-4.1A)
 1.38A 3ag3G-3zyvA:
undetectable
3ag3N-3zyvA:
0.3
3ag3O-3zyvA:
undetectable		 3ag3G-3zyvA:
4.98
3ag3N-3zyvA:
18.19
3ag3O-3zyvA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3zyv AOX3
(Mus
musculus) 		3 / 3 PHE A1270
CYH A1273
PHE A1277
 None
 1.06A 3cr5X-3zyvA:
undetectable		 3cr5X-3zyvA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3zyv AOX3
(Mus
musculus) 		3 / 3 CYH A1273
PHE A1276
PHE A1277
 None
 0.90A 3cr5X-3zyvA:
undetectable		 3cr5X-3zyvA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3zyv AOX3
(Mus
musculus) 		5 / 9 PHE A1270
PRO A 922
GLY A1268
ILE A1183
GLY A1207
 None
 1.40A 3csjB-3zyvA:
undetectable		 3csjB-3zyvA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 VAL A 667
ASN A 909
ILE A 700
ASP A 705
ILE A 696
 None
 1.21A 3ddyA-3zyvA:
undetectable		 3ddyA-3zyvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLN A 340
ILE A 333
LEU A 341
CYH A 377
LEU A 392
 None
 1.13A 3dzuA-3zyvA:
undetectable		 3dzuA-3zyvA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3zyv AOX3
(Mus
musculus) 		3 / 3 GLU A1242
SER A1165
VAL A1275
 None
 0.85A 3eeoA-3zyvA:
undetectable		 3eeoA-3zyvA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3zyv AOX3
(Mus
musculus) 		5 / 10 GLY A1265
GLN A1045
ASP A1196
VAL A1159
VAL A1012
 MTE  A3003 ( 4.2A)
MTE  A3003 (-4.1A)
None
None
None
 1.35A 3fhjA-3zyvA:
undetectable		 3fhjA-3zyvA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A1265
GLN A1045
ASP A1196
VAL A1159
VAL A1012
 MTE  A3003 ( 4.2A)
MTE  A3003 (-4.1A)
None
None
None
 1.40A 3fi0H-3zyvA:
undetectable		 3fi0H-3zyvA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3zyv AOX3
(Mus
musculus) 		5 / 12 LEU A 890
PHE A1270
ALA A 886
LEU A 741
THR A1269
 None
 1.14A 3gwuA-3zyvA:
undetectable		 3gwuA-3zyvA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A1258
GLY A1092
ALA A1024
ALA A1055
VAL A1054
 None
 0.82A 3jb2A-3zyvA:
undetectable		 3jb2A-3zyvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A1258
GLY A1092
ALA A1024
ALA A1055
VAL A1054
 None
 0.82A 3jb3A-3zyvA:
undetectable		 3jb3A-3zyvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLY A 595
CYH A  52
CYH A 152
PHE A 803
 None
FES  A3002 (-2.3A)
FES  A3001 (-2.2A)
MTE  A3003 (-4.1A)
 1.03A 3ko0D-3zyvA:
undetectable
3ko0E-3zyvA:
undetectable		 3ko0D-3zyvA:
5.92
3ko0E-3zyvA:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ALA A 164
PRO A 159
GLY A 112
PRO A 138
LEU A 131
 None
 1.10A 3m6vA-3zyvA:
undetectable		 3m6vA-3zyvA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ALA A 164
PRO A 159
GLY A 112
PRO A 138
LEU A 131
 None
 1.05A 3m6vB-3zyvA:
undetectable		 3m6vB-3zyvA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A  53
GLN A 348
MET A 124
CYH A 152
ILE A1234
 FES  A3002 (-3.9A)
None
None
FES  A3001 (-2.2A)
None
 1.37A 3mnoA-3zyvA:
undetectable		 3mnoA-3zyvA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A  53
GLN A 348
MET A 124
CYH A 152
ILE A1234
 FES  A3002 (-3.9A)
None
None
FES  A3001 (-2.2A)
None
 1.36A 3mnpA-3zyvA:
undetectable		 3mnpA-3zyvA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3zyv AOX3
(Mus
musculus) 		4 / 6 LEU A 812
GLU A 656
SER A 808
THR A 914
 None
 1.42A 3ropA-3zyvA:
undetectable		 3ropA-3zyvA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3zyv AOX3
(Mus
musculus) 		3 / 3 HIS A 135
SER A  70
ASN A 317
 None
 0.91A 3s8pB-3zyvA:
undetectable		 3s8pB-3zyvA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLN A 923
PHE A 919
GLY A 920
GLY A 805
 None
 0.60A 3v3nB-3zyvA:
undetectable		 3v3nB-3zyvA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLN A 923
PHE A 919
GLY A 920
GLY A 805
 None
 0.59A 3v3nC-3zyvA:
undetectable		 3v3nC-3zyvA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 3zyv AOX3
(Mus
musculus) 		4 / 6 VAL A 781
LEU A 785
ILE A 787
VAL A 756
 None
 0.94A 4a9kA-3zyvA:
2.1		 4a9kA-3zyvA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3zyv AOX3
(Mus
musculus) 		3 / 3 TYR A1232
PHE A 916
ARG A 153
 None
 1.19A 4g19D-3zyvA:
undetectable		 4g19D-3zyvA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4jksA-3zyvA:
undetectable		 4jksA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4jksB-3zyvA:
undetectable		 4jksB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.87A 4jkuA-3zyvA:
undetectable		 4jkuA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 333
ALA A 336
GLN A 340
LEU A 368
ALA A 427
 None
 0.53A 4k6iA-3zyvA:
undetectable		 4k6iA-3zyvA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4k8cA-3zyvA:
undetectable		 4k8cA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.89A 4k8cB-3zyvA:
undetectable		 4k8cB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4k8kA-3zyvA:
undetectable		 4k8kA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4k8kB-3zyvA:
undetectable		 4k8kB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4kahA-3zyvA:
undetectable		 4kahA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.89A 4kahB-3zyvA:
undetectable		 4kahB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4kalA-3zyvA:
undetectable		 4kalA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4kalB-3zyvA:
undetectable		 4kalB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.87A 4kanA-3zyvA:
undetectable		 4kanA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4kanB-3zyvA:
undetectable		 4kanB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.89A 4kbeA-3zyvA:
undetectable		 4kbeA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4kbeB-3zyvA:
undetectable		 4kbeB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4lbgA-3zyvA:
undetectable		 4lbgA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.87A 4lbgB-3zyvA:
undetectable		 4lbgB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4lcaA-3zyvA:
undetectable		 4lcaA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 590
GLY A 589
ILE A 109
GLU A 596
THR A 121
 None
 0.88A 4lcaB-3zyvA:
undetectable		 4lcaB-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ASP A1089
VAL A1159
TYR A1157
SER A1261
GLY A1187
 None
 1.10A 4mm6A-3zyvA:
undetectable		 4mm6A-3zyvA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3zyv AOX3
(Mus
musculus) 		5 / 10 ASP A1089
PRO A1015
ALA A1143
TYR A1141
PHE A1014
 None
 1.31A 4mmdA-3zyvA:
undetectable		 4mmdA-3zyvA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3zyv AOX3
(Mus
musculus) 		5 / 9 ASP A1089
VAL A1159
TYR A1157
SER A1261
GLY A1187
 None
 1.09A 4mmfA-3zyvA:
undetectable		 4mmfA-3zyvA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLY A  86
ILE A  11
GLU A 221
LEU A 222
 None
 0.74A 4mwzB-3zyvA:
undetectable		 4mwzB-3zyvA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 LEU A 707
GLY A 873
GLY A 872
ASN A 913
ALA A 706
 None
None
NA  A2337 (-4.0A)
None
None
 1.01A 4n09B-3zyvA:
undetectable		 4n09B-3zyvA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A 652
LEU A 812
MET A 780
VAL A 781
ILE A 670
 None
 1.30A 4okbA-3zyvA:
undetectable		 4okbA-3zyvA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ASP A 836
PRO A1229
THR A 751
ILE A 831
 None
 1.07A 4pcuA-3zyvA:
undetectable		 4pcuA-3zyvA:
17.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3zyv AOX3
(Mus
musculus) 		5 / 8 ASP A 578
SER A1056
ARG A1057
PRO A1062
TRP A1121
 None
 0.53A 4uhxA-3zyvA:
42.5		 4uhxA-3zyvA:
61.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3zyv AOX3
(Mus
musculus) 		5 / 8 ASP A 578
SER A1056
PRO A1062
TRP A1118
TRP A1121
 None
 1.12A 4uhxA-3zyvA:
42.5		 4uhxA-3zyvA:
61.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 ASP A 578
SER A1056
ARG A1057
PRO A1062
 None
 0.52A 4uhxA-3zyvA:
42.5		 4uhxA-3zyvA:
61.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 ASP A 578
SER A1056
PRO A1062
TRP A1118
 None
 1.03A 4uhxA-3zyvA:
42.5		 4uhxA-3zyvA:
61.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLU A1058
ILE A 580
PRO A 579
ILE A1191
SER A1261
 None
 1.19A 4uroC-3zyvA:
undetectable		 4uroC-3zyvA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3zyv AOX3
(Mus
musculus) 		5 / 10 ASP A1089
VAL A1159
ASP A1186
SER A1261
GLY A1187
 None
 1.19A 4xp1A-3zyvA:
undetectable		 4xp1A-3zyvA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3zyv AOX3
(Mus
musculus) 		5 / 10 VAL A1159
ASP A1186
SER A1261
SER A1188
GLY A1187
 None
 1.27A 4xp1A-3zyvA:
undetectable		 4xp1A-3zyvA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3zyv AOX3
(Mus
musculus) 		4 / 6 LYS A1217
GLU A1215
GLY A 742
GLY A 743
 None
 0.93A 5a06D-3zyvA:
2.2		 5a06D-3zyvA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyv AOX3
(Mus
musculus) 		5 / 11 GLY A1083
GLN A1045
ARG A 917
PHE A 803
GLY A 804
 MTE  A3003 (-3.6A)
MTE  A3003 (-4.1A)
MTE  A3003 ( 2.9A)
MTE  A3003 (-4.1A)
MOS  A3004 (-2.8A)
 1.10A 5b1bA-3zyvA:
2.2
5b1bB-3zyvA:
undetectable
5b1bT-3zyvA:
undetectable		 5b1bA-3zyvA:
18.19
5b1bB-3zyvA:
10.10
5b1bT-3zyvA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ALA A 353
ASP A  51
GLY A 149
THR A1238
 FAD  A3005 (-3.6A)
None
None
None
 0.83A 5bs8A-3zyvA:
undetectable
5bs8C-3zyvA:
undetectable
5bs8D-3zyvA:
undetectable		 5bs8A-3zyvA:
16.25
5bs8C-3zyvA:
16.25
5bs8D-3zyvA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ARG A 429
ALA A 431
GLY A 346
THR A  75
 FAD  A3005 ( 4.9A)
None
None
FES  A3002 ( 4.3A)
 0.85A 5bs8A-3zyvA:
undetectable
5bs8C-3zyvA:
undetectable
5bs8D-3zyvA:
undetectable		 5bs8A-3zyvA:
16.25
5bs8C-3zyvA:
16.25
5bs8D-3zyvA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3zyv AOX3
(Mus
musculus) 		4 / 6 ALA A 431
GLY A 346
THR A  75
ARG A 429
 None
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.9A)
 0.82A 5btgA-3zyvA:
undetectable
5btgB-3zyvA:
undetectable
5btgC-3zyvA:
undetectable		 5btgA-3zyvA:
16.25
5btgB-3zyvA:
11.85
5btgC-3zyvA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ALA A 353
ASP A  51
GLY A 149
THR A1238
 FAD  A3005 (-3.6A)
None
None
None
 0.78A 5btgA-3zyvA:
undetectable
5btgC-3zyvA:
undetectable
5btgD-3zyvA:
undetectable		 5btgA-3zyvA:
16.25
5btgC-3zyvA:
16.25
5btgD-3zyvA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3zyv AOX3
(Mus
musculus) 		4 / 6 GLU A 107
GLY A1044
ARG A 798
GLY A 118
 None
MTE  A3003 (-3.8A)
None
FES  A3001 (-4.4A)
 0.89A 5cdnA-3zyvA:
undetectable
5cdnB-3zyvA:
undetectable		 5cdnA-3zyvA:
16.60
5cdnB-3zyvA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3zyv AOX3
(Mus
musculus) 		3 / 3 HIS A 135
SER A  70
ASN A 317
 None
 0.89A 5cprB-3zyvA:
undetectable		 5cprB-3zyvA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.50A 5eezQ-3zyvA:
undetectable
5eezR-3zyvA:
undetectable		 5eezQ-3zyvA:
4.62
5eezR-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.50A 5ef1Q-3zyvA:
undetectable
5ef1R-3zyvA:
undetectable		 5ef1Q-3zyvA:
4.62
5ef1R-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3zyv AOX3
(Mus
musculus) 		5 / 9 GLY A  50
THR A  56
THR A  75
ILE A 349
SER A 127
 FES  A3002 ( 3.1A)
None
FES  A3002 ( 4.3A)
FAD  A3005 ( 4.3A)
None
 1.50A 5ef3Q-3zyvA:
undetectable
5ef3R-3zyvA:
undetectable		 5ef3Q-3zyvA:
4.62
5ef3R-3zyvA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3zyv AOX3
(Mus
musculus) 		4 / 5 ALA A 262
TYR A 282
GLY A 346
LEU A 273
 None
 0.92A 5eslA-3zyvA:
undetectable		 5eslA-3zyvA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3zyv AOX3
(Mus
musculus) 		4 / 6 SER A  73
GLY A  53
ASN A 150
ILE A 349
 None
FES  A3002 (-3.9A)
None
FAD  A3005 ( 4.3A)
 1.08A 5j4nA-3zyvA:
undetectable		 5j4nA-3zyvA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3zyv AOX3
(Mus
musculus) 		4 / 6 ILE A 734
GLY A 859
ASN A 858
ILE A 853
 None
 0.85A 5j4nB-3zyvA:
undetectable		 5j4nB-3zyvA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 LEU A 881
LEU A 741
GLY A 918
PHE A 919
ALA A 925
 None
 1.18A 5j7wC-3zyvA:
undetectable		 5j7wC-3zyvA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3zyv AOX3
(Mus
musculus) 		3 / 3 VAL A 905
ARG A 917
PRO A 922
 None
MTE  A3003 ( 2.9A)
None
 0.83A 5koxA-3zyvA:
undetectable		 5koxA-3zyvA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3zyv AOX3
(Mus
musculus) 		4 / 7 PRO A1156
TYR A1141
SER A1188
ASN A1254
 None
 1.11A 5l1fC-3zyvA:
undetectable		 5l1fC-3zyvA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3zyv AOX3
(Mus
musculus) 		3 / 3 SER A1219
TYR A1218
TYR A1225
 None
 0.92A 5lakC-3zyvA:
undetectable
5lakJ-3zyvA:
undetectable		 5lakC-3zyvA:
13.03
5lakJ-3zyvA:
0.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLU A1042
GLY A 118
GLN A 116
THR A 115
 None
FES  A3001 (-4.4A)
MTE  A3003 (-4.0A)
None
 0.99A 5sxqA-3zyvA:
undetectable		 5sxqA-3zyvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLU A1042
GLY A 118
GLN A 116
THR A 115
 None
FES  A3001 (-4.4A)
MTE  A3003 (-4.0A)
None
 0.99A 5sxtA-3zyvA:
undetectable		 5sxtA-3zyvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3zyv AOX3
(Mus
musculus) 		4 / 8 GLU A1042
GLY A 118
GLN A 116
THR A 115
 None
FES  A3001 (-4.4A)
MTE  A3003 (-4.0A)
None
 0.96A 5sxtB-3zyvA:
undetectable		 5sxtB-3zyvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3zyv AOX3
(Mus
musculus) 		4 / 7 THR A 121
VAL A1205
GLN A 744
GLU A 745
 None
 1.12A 5tudA-3zyvA:
undetectable		 5tudA-3zyvA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zyv AOX3
(Mus
musculus) 		4 / 7 PRO A 288
ILE A 286
SER A 354
THR A 308
 None
None
FAD  A3005 (-2.8A)
FAD  A3005 (-2.9A)
 0.97A 5vkqA-3zyvA:
undetectable
5vkqD-3zyvA:
undetectable		 5vkqA-3zyvA:
22.19
5vkqD-3zyvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zyv AOX3
(Mus
musculus) 		4 / 7 SER A 354
THR A 308
PRO A 288
ILE A 286
 FAD  A3005 (-2.8A)
FAD  A3005 (-2.9A)
None
None
 1.00A 5vkqA-3zyvA:
undetectable
5vkqB-3zyvA:
undetectable		 5vkqA-3zyvA:
22.19
5vkqB-3zyvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zyv AOX3
(Mus
musculus) 		4 / 8 SER A 354
THR A 308
PRO A 288
ILE A 286
 FAD  A3005 (-2.8A)
FAD  A3005 (-2.9A)
None
None
 0.97A 5vkqB-3zyvA:
undetectable
5vkqC-3zyvA:
0.6		 5vkqB-3zyvA:
22.19
5vkqC-3zyvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zyv AOX3
(Mus
musculus) 		4 / 7 SER A 354
THR A 308
PRO A 288
ILE A 286
 FAD  A3005 (-2.8A)
FAD  A3005 (-2.9A)
None
None
 0.99A 5vkqC-3zyvA:
0.6
5vkqD-3zyvA:
undetectable		 5vkqC-3zyvA:
22.19
5vkqD-3zyvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ARG A 917
PHE A 803
GLY A 804
GLY A1083
GLN A1045
 MTE  A3003 ( 2.9A)
MTE  A3003 (-4.1A)
MOS  A3004 (-2.8A)
MTE  A3003 (-3.6A)
MTE  A3003 (-4.1A)
 1.28A 5x19G-3zyvA:
undetectable
5x19N-3zyvA:
2.2
5x19O-3zyvA:
undetectable		 5x19G-3zyvA:
4.98
5x19N-3zyvA:
18.19
5x19O-3zyvA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3zyv AOX3
(Mus
musculus) 		5 / 11 ARG A 917
PHE A 803
GLY A 805
GLY A1083
GLN A1045
 MTE  A3003 ( 2.9A)
MTE  A3003 (-4.1A)
None
MTE  A3003 (-3.6A)
MTE  A3003 (-4.1A)
 1.49A 5x19G-3zyvA:
undetectable
5x19N-3zyvA:
2.2
5x19O-3zyvA:
undetectable		 5x19G-3zyvA:
4.98
5x19N-3zyvA:
18.19
5x19O-3zyvA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A1087
GLY A1265
GLY A1263
ALA A1203
GLN A1206
 MTE  A3003 (-2.8A)
MTE  A3003 ( 4.2A)
None
None
None
 1.23A 5x7fA-3zyvA:
undetectable		 5x7fA-3zyvA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ILE A 333
ALA A 336
GLN A 340
LEU A 368
ALA A 427
 None
 0.67A 6a60D-3zyvA:
undetectable		 6a60D-3zyvA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 ASP A1089
ALA A1022
GLY A1083
GLY A1087
VAL A1080
 None
None
MTE  A3003 (-3.6A)
MTE  A3003 (-2.8A)
None
 1.19A 6clxA-3zyvA:
undetectable		 6clxA-3zyvA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3zyv AOX3
(Mus
musculus) 		5 / 9 LEU A  31
GLY A 123
THR A  91
VAL A  57
CYH A  55
 None
None
None
None
FES  A3002 (-2.2A)
 1.27A 6czmD-3zyvA:
undetectable
6czmE-3zyvA:
undetectable		 6czmD-3zyvA:
14.07
6czmE-3zyvA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 3zyv AOX3
(Mus
musculus) 		4 / 7 ASP A1239
GLN A 434
GLY A 149
SER A1236
 None
 0.73A 6ekzA-3zyvA:
undetectable		 6ekzA-3zyvA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 3zyv AOX3
(Mus
musculus) 		5 / 12 GLY A 373
LEU A 372
VAL A 416
GLY A 465
HIS A 358
 None
None
None
None
FAD  A3005 (-3.8A)
 0.81A 6gngA-3zyvA:
undetectable		 6gngA-3zyvA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zyv AOX3
(Mus
musculus) 		4 / 5 GLY A1040
THR A1082
SER A 770
SER A 771
 None
MTE  A3003 (-4.3A)
None
None
 1.08A 6jmjA-3zyvA:
undetectable		 6jmjA-3zyvA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3zyv AOX3
(Mus
musculus) 		4 / 8 HIS A 358
GLY A 356
LEU A 306
GLY A 307
 FAD  A3005 (-3.8A)
FAD  A3005 ( 4.8A)
None
None
 0.77A 6mdqA-3zyvA:
1.4		 6mdqA-3zyvA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3zyv AOX3
(Mus
musculus) 		4 / 4 ASP A 640
ILE A 828
PRO A 827
LEU A 610
 None
 1.33A 6mkeB-3zyvA:
undetectable		 6mkeB-3zyvA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3zyv AOX3
(Mus
musculus) 		4 / 4 ASP A 640
ILE A 828
PRO A 827
LEU A 610
 None
 1.35A 6mkeA-3zyvA:
undetectable		 6mkeA-3zyvA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 LEU A 881
LEU A 741
GLY A 918
PHE A 919
ALA A 925
 None
 1.24A 6qyaB-3zyvA:
undetectable		 6qyaB-3zyvA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 3zyv AOX3
(Mus
musculus) 		5 / 12 LEU A 881
LEU A 741
GLY A 918
PHE A 919
ALA A 925
 None
 1.24A 6qyaD-3zyvA:
undetectable		 6qyaD-3zyvA:
13.15