SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ILE A 432
GLY A 353
PHE A 434
VAL A 469
ALA A 422
 None
 1.13A 1axwA-3zz1A:
undetectable		 1axwA-3zz1A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 SER A 482
VAL A 483
GLY A 484
GLU A 166
 None
 0.73A 1fduD-3zz1A:
3.9		 1fduD-3zz1A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 9 THR A  76
PRO A  77
GLY A  78
THR A  84
GLY A 330
 None
 1.26A 1h4oE-3zz1A:
undetectable
1h4oF-3zz1A:
undetectable		 1h4oE-3zz1A:
13.88
1h4oF-3zz1A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 ILE A 358
GLY A 359
PRO A 395
ASN A 414
 None
 1.00A 1oniG-3zz1A:
undetectable
1oniI-3zz1A:
undetectable		 1oniG-3zz1A:
11.67
1oniI-3zz1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 GLY A  78
GLN A  80
VAL A 529
ALA A  82
 None
 1.03A 1p6kA-3zz1A:
undetectable		 1p6kA-3zz1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 GLY A 147
SER A  69
ILE A 311
GLY A 105
ILE A 106
 None
 1.09A 1q8jB-3zz1A:
4.5		 1q8jB-3zz1A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ILE A 399
ILE A 432
PHE A 434
ILE A 477
VAL A 517
 None
 0.92A 1qhsA-3zz1A:
undetectable		 1qhsA-3zz1A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ILE A 399
ILE A 432
PHE A 434
ILE A 477
VAL A 517
 None
 0.91A 1qhyA-3zz1A:
2.2		 1qhyA-3zz1A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		3 / 3 ALA A 485
VAL A 483
TRP A 459
 None
 0.74A 1tkqA-3zz1A:
undetectable		 1tkqA-3zz1A:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ILE A 432
GLY A 353
PHE A 434
VAL A 469
ALA A 422
 None
 1.10A 1tlsB-3zz1A:
undetectable		 1tlsB-3zz1A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 10 GLY A 111
GLU A 128
GLY A  62
THR A 156
VAL A 113
 None
 1.03A 1v3qE-3zz1A:
undetectable		 1v3qE-3zz1A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ASP A 236
ARG A 169
HIS A 159
ARG A 125
LEU A  64
 None
 1.32A 1ynnC-3zz1A:
undetectable		 1ynnC-3zz1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 SER A 578
SER A 523
THR A 580
ASN A 623
 None
 1.46A 1yvpA-3zz1A:
4.4		 1yvpA-3zz1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 GLY A 574
PRO A 569
ALA A 533
ILE A 532
 None
 0.92A 2aofA-3zz1A:
undetectable		 2aofA-3zz1A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 8 ILE A 349
SER A 348
ASP A 429
LEU A 343
 None
 1.00A 2cdqA-3zz1A:
undetectable		 2cdqA-3zz1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 LEU A  23
ALA A  49
THR A  46
VAL A 289
LEU A 271
 None
 1.02A 2g78A-3zz1A:
undetectable		 2g78A-3zz1A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ALA A 114
ALA A 140
ALA A 157
PRO A  63
GLY A 115
 None
 1.27A 2igtC-3zz1A:
3.7		 2igtC-3zz1A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 ARG A 291
GLY A 231
PHE A 229
PRO A 604
 None
 1.00A 2m2oB-3zz1A:
undetectable		 2m2oB-3zz1A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 ILE A 326
ARG A  93
PRO A 395
GLY A 379
 None
 1.23A 2pnjB-3zz1A:
undetectable		 2pnjB-3zz1A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 TYR A 135
THR A 137
ALA A 140
PRO A 134
 None
 1.28A 2ql8A-3zz1A:
undetectable
2ql8B-3zz1A:
undetectable		 2ql8A-3zz1A:
12.01
2ql8B-3zz1A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 10 ALA A 425
ASN A 473
ALA A 472
ALA A 422
SER A 423
 None
 1.38A 2r2vC-3zz1A:
undetectable
2r2vF-3zz1A:
undetectable
2r2vG-3zz1A:
undetectable		 2r2vC-3zz1A:
3.09
2r2vF-3zz1A:
3.09
2r2vG-3zz1A:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 PHE A 189
ILE A 172
ILE A 543
GLY A 115
 None
 1.00A 2v0mB-3zz1A:
undetectable		 2v0mB-3zz1A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 TYR A 204
ARG A 169
GLU A 441
SER A 384
 None
 1.23A 2zt7A-3zz1A:
undetectable		 2zt7A-3zz1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		3 / 3 TYR A 217
TYR A 160
ILE A 161
 None
 0.74A 3eteA-3zz1A:
undetectable
3eteB-3zz1A:
2.8		 3eteA-3zz1A:
22.19
3eteB-3zz1A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 4 GLY A 605
VAL A 193
GLY A 138
THR A 137
 None
 0.84A 3ib2A-3zz1A:
undetectable		 3ib2A-3zz1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 ARG A 453
ALA A 437
SER A 482
VAL A 480
 None
 0.79A 3o14A-3zz1A:
undetectable		 3o14A-3zz1A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		3 / 3 ASN A 473
ALA A 425
LYS A 428
 None
 0.66A 3runA-3zz1A:
undetectable		 3runA-3zz1A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 SER A 439
SER A 482
VAL A 483
GLY A 123
 None
 1.03A 3rxhA-3zz1A:
undetectable		 3rxhA-3zz1A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 SER A 439
SER A 482
VAL A 483
GLY A 124
 None
 1.08A 3rxhA-3zz1A:
undetectable		 3rxhA-3zz1A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 GLY A 574
GLY A 698
PHE A 669
ALA A 655
ALA A 667
 None
 1.16A 3sueB-3zz1A:
undetectable		 3sueB-3zz1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 GLY A 574
GLY A 698
PHE A 669
ALA A 655
ALA A 667
 None
 1.11A 3sueC-3zz1A:
undetectable		 3sueC-3zz1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 11 GLY A 574
GLY A 698
PHE A 669
ALA A 655
ALA A 667
 None
 1.14A 3sufC-3zz1A:
undetectable		 3sufC-3zz1A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 9 ILE A  90
ALA A  81
VAL A 529
PHE A 130
LEU A 136
 None
 1.31A 3ti1A-3zz1A:
undetectable		 3ti1A-3zz1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 ILE A 432
GLY A 353
PHE A 434
VAL A 469
ALA A 422
 None
 1.19A 4foxD-3zz1A:
undetectable		 4foxD-3zz1A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 LEU A 117
ARG A 674
PRO A 176
SER A 174
 None
 1.26A 4klrA-3zz1A:
2.3		 4klrA-3zz1A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 VAL A 497
HIS A 481
LEU A 514
LEU A 518
 None
 0.99A 4l1wA-3zz1A:
4.2		 4l1wA-3zz1A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 VAL A 469
ALA A 472
GLY A 353
SER A 420
SER A 423
 None
 1.19A 4mmdB-3zz1A:
undetectable		 4mmdB-3zz1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 LEU A 341
ILE A 432
LEU A 514
LEU A 528
 None
 0.87A 4o8fA-3zz1A:
undetectable		 4o8fA-3zz1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 TYR A 636
GLN A 634
ASP A 558
ASP A 538
 None
 1.34A 4qtuB-3zz1A:
undetectable		 4qtuB-3zz1A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 TYR A 443
GLY A 381
GLY A 440
ALA A 386
ARG A  93
 None
 1.18A 4qtuD-3zz1A:
undetectable		 4qtuD-3zz1A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 TYR A 204
GLY A 442
GLU A 441
ASP A 370
 None
 1.33A 5emlA-3zz1A:
4.1		 5emlA-3zz1A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 VAL A 466
ALA A 470
GLN A 496
VAL A 497
 None
 0.71A 5i8fA-3zz1A:
undetectable		 5i8fA-3zz1A:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 TYR A  54
ILE A 292
LEU A 110
GLY A 111
PRO A 112
 None
 1.14A 5ienA-3zz1A:
undetectable		 5ienA-3zz1A:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 LEU A 334
LEU A 341
VAL A 480
GLY A 504
ALA A 503
 None
 1.01A 5jw1B-3zz1A:
undetectable		 5jw1B-3zz1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 8 ARG A 169
GLU A 166
GLY A 115
PRO A 116
 None
 1.14A 5kf8A-3zz1A:
undetectable		 5kf8A-3zz1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 8 ARG A 169
GLU A 166
GLY A 115
PRO A 116
 None
 0.99A 5kgpA-3zz1A:
undetectable		 5kgpA-3zz1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 8 ARG A 169
GLU A 166
GLY A 115
PRO A 116
 None
 0.99A 5kgpB-3zz1A:
undetectable		 5kgpB-3zz1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		6 / 12 ASP A  61
ARG A 125
LYS A 158
HIS A 159
MET A 201
GLU A 441
 None
 0.46A 5m6gA-3zz1A:
30.5		 5m6gA-3zz1A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 5 THR A 436
HIS A 481
ALA A 355
ASP A 374
 None
 1.39A 5mfxA-3zz1A:
2.1		 5mfxA-3zz1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		3 / 3 SER A 199
ALA A 198
THR A 299
 None
 0.68A 5n0xB-3zz1A:
undetectable		 5n0xB-3zz1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 12 SER A 104
ASN A 310
SER A  72
GLY A  71
THR A  70
 None
NAG  A 911 (-1.8A)
None
None
None
 1.22A 5oj0A-3zz1A:
undetectable		 5oj0A-3zz1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 9 TYR A 530
ASP A 558
GLY A 131
ALA A  82
VAL A  79
 None
 1.31A 5v3cA-3zz1A:
undetectable		 5v3cA-3zz1A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 LEU A 334
LYS A 534
GLU A 489
LEU A 492
 None
 1.32A 5xooA-3zz1A:
undetectable		 5xooA-3zz1A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 6 VAL A 529
LEU A 514
ARG A 324
PRO A 506
 None
 1.19A 6brdB-3zz1A:
undetectable		 6brdB-3zz1A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		6 / 12 GLY A 574
ILE A 621
GLY A 698
PHE A 669
ALA A 655
ALA A 667
 None
 1.20A 6c2mD-3zz1A:
undetectable		 6c2mD-3zz1A:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		4 / 7 ASN A 417
GLY A 471
ALA A 470
VAL A 478
 None
 0.82A 6dwnB-3zz1A:
undetectable		 6dwnB-3zz1A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE
(Trichoderma
reesei) 		5 / 10 GLY A 440
GLY A 124
VAL A 483
GLU A 166
ASN A 449
 None
 1.14A 6nqaK-3zz1A:
undetectable		 6nqaK-3zz1A:
19.46