SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 8 VAL A 322
LEU A 325
PRO A 320
MET A 358
 None
 1.03A 1fduB-3zzuA:
undetectable		 1fduB-3zzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 7 THR A 248
VAL A 103
GLY A 101
ILE A  13
 None
 0.73A 1gtnC-3zzuA:
undetectable
1gtnD-3zzuA:
undetectable		 1gtnC-3zzuA:
7.11
1gtnD-3zzuA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 5 GLU A 455
ARG A 626
ASP A 622
THR A 662
 None
 1.44A 1k4tA-3zzuA:
undetectable		 1k4tA-3zzuA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 10 ASP A 622
GLY A 621
VAL A 623
MET A 611
GLY A 617
 None
 1.25A 1pn0C-3zzuA:
undetectable		 1pn0C-3zzuA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 10 ASP A 622
GLY A 621
VAL A 623
MET A 611
GLY A 617
 None
 1.24A 1pn0D-3zzuA:
undetectable		 1pn0D-3zzuA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 11 LEU A  96
LEU A  99
LEU A 278
PRO A 279
VAL A 251
 None
 1.32A 2po5B-3zzuA:
3.0		 2po5B-3zzuA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 ASP A 100
THR A  82
PRO A  83
 None
 0.72A 2pynB-3zzuA:
undetectable		 2pynB-3zzuA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 11 LEU A 257
ILE A 162
PHE A 144
ALA A 159
LEU A 214
 None
 1.18A 2q72A-3zzuA:
undetectable		 2q72A-3zzuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 ASP A 100
THR A  82
PRO A  83
 None
 0.70A 2qakB-3zzuA:
undetectable		 2qakB-3zzuA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 11 LEU A 257
ILE A 162
PHE A 144
ALA A 159
LEU A 214
 None
 1.10A 2qjuA-3zzuA:
undetectable		 2qjuA-3zzuA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 10 MET A 335
PHE A 309
ALA A 311
THR A 326
LEU A 380
 None
 1.31A 2wuzA-3zzuA:
undetectable		 2wuzA-3zzuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 10 MET A 335
PHE A 309
ALA A 311
THR A 326
LEU A 380
 None
 1.31A 2wuzB-3zzuA:
undetectable		 2wuzB-3zzuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 VAL A 462
ALA A 426
GLN A 425
LEU A 427
VAL A 475
 None
 0.79A 3fc6C-3zzuA:
undetectable		 3fc6C-3zzuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 LEU A 257
ILE A 162
PHE A 144
ALA A 159
LEU A 214
 None
 1.03A 3gwvA-3zzuA:
undetectable		 3gwvA-3zzuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_B_TPFB490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 9 MET A 335
PHE A 309
ALA A 311
THR A 326
LEU A 380
 None
 1.31A 3l4dB-3zzuA:
undetectable		 3l4dB-3zzuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_C_TPFC490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 9 MET A 335
PHE A 309
ALA A 311
THR A 326
LEU A 380
 None
 1.29A 3l4dC-3zzuA:
undetectable		 3l4dC-3zzuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 THR A 385
THR A 326
ALA A 376
ALA A  66
SER A  65
 None
 1.15A 3mg02-3zzuA:
undetectable
3mg0V-3zzuA:
undetectable		 3mg02-3zzuA:
15.80
3mg0V-3zzuA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 ARG A  94
LEU A 312
THR A 383
 None
 0.82A 3oxcA-3zzuA:
undetectable		 3oxcA-3zzuA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 ARG A 130
ALA A 123
ILE A 131
MET A 270
LYS A  23
 None
 1.48A 3qt0A-3zzuA:
undetectable		 3qt0A-3zzuA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 6 PHE A 309
LEU A 355
PHE A 328
ALA A 313
THR A 326
 None
 1.46A 3t3zA-3zzuA:
undetectable		 3t3zA-3zzuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 5 PHE A 309
PHE A 328
ALA A 313
THR A 326
 None
 1.21A 3t3zC-3zzuA:
undetectable		 3t3zC-3zzuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 6 PHE A 309
LEU A 355
PHE A 328
ALA A 313
THR A 326
 None
 1.47A 3t3zD-3zzuA:
undetectable		 3t3zD-3zzuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 8 GLU A  93
GLU A 399
ILE A 288
LEU A 398
 None
 0.94A 4mj8A-3zzuA:
undetectable		 4mj8A-3zzuA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 5 ASP A 283
LEU A 282
ARG A   3
THR A 249
 None
 1.44A 4p3qA-3zzuA:
undetectable		 4p3qA-3zzuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 SER A  65
THR A 385
THR A 326
ALA A 376
ALA A  66
 None
 1.17A 4qvnV-3zzuA:
undetectable
4qvnb-3zzuA:
undetectable		 4qvnV-3zzuA:
17.44
4qvnb-3zzuA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 SER A  65
THR A 385
THR A 326
ALA A 376
ALA A  66
 None
 1.17A 4qvnH-3zzuA:
undetectable
4qvnN-3zzuA:
undetectable		 4qvnH-3zzuA:
17.44
4qvnN-3zzuA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 6 LEU A 257
LEU A 271
THR A  26
VAL A 105
 None
 1.05A 4udaA-3zzuA:
undetectable		 4udaA-3zzuA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 6 ASP A 305
ALA A 303
THR A 334
TYR A 370
 None
 1.22A 4w5rA-3zzuA:
3.4		 4w5rA-3zzuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 6 ASP A 305
ALA A 303
THR A 334
TYR A 370
 None
 1.29A 4w5tA-3zzuA:
3.2		 4w5tA-3zzuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 6 GLU A 517
GLY A 519
GLY A 521
ASP A 561
 None
 1.03A 5a06D-3zzuA:
3.6		 5a06D-3zzuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 5 TYR A 186
PHE A 144
LEU A 257
PRO A 165
 None
 1.37A 5csyB-3zzuA:
undetectable		 5csyB-3zzuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 ARG A 464
LYS A 429
GLU A 433
 None
 0.69A 5d0yA-3zzuA:
undetectable		 5d0yA-3zzuA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 PRO A 603
ILE A 609
SER A 481
 None
 0.73A 5fsaA-3zzuA:
undetectable		 5fsaA-3zzuA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 VAL A 630
ASP A 631
LEU A 658
ASP A 622
THR A 667
 None
 1.28A 5hnzB-3zzuA:
undetectable		 5hnzB-3zzuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 TYR A 186
TYR A  33
GLN A 268
 None
 1.03A 5jsdA-3zzuA:
undetectable
5jsdB-3zzuA:
undetectable		 5jsdA-3zzuA:
21.95
5jsdB-3zzuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 TYR A 186
TYR A  33
GLN A 268
 None
 1.03A 5jsdB-3zzuA:
undetectable
5jsdC-3zzuA:
undetectable		 5jsdB-3zzuA:
21.95
5jsdC-3zzuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 LYS A 606
ASP A 673
ARG A 629
 None
 1.02A 5jwaA-3zzuA:
undetectable
5jwaH-3zzuA:
undetectable		 5jwaA-3zzuA:
21.42
5jwaH-3zzuA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 4 GLN A 115
THR A 118
GLU A 610
LEU A 658
 None
 1.45A 5m66A-3zzuA:
3.4		 5m66A-3zzuA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 VAL A 148
HIS A 152
ALA A 159
PHE A 253
LEU A 214
 None
 1.32A 5nd4B-3zzuA:
3.8		 5nd4B-3zzuA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 8 TYR A  33
ASP A 189
VAL A 267
GLY A 266
 None
 0.94A 5nzyA-3zzuA:
undetectable		 5nzyA-3zzuA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 8 VAL A 412
VAL A 448
LEU A 427
THR A 424
 None
 0.80A 5tt3F-3zzuA:
undetectable		 5tt3F-3zzuA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 8 ARG A 245
GLN A 246
VAL A 284
ASP A 283
 None
 1.02A 5vlmA-3zzuA:
undetectable		 5vlmA-3zzuA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		4 / 4 GLY A 101
ARG A 329
ASN A  12
LEU A  99
 None
 1.31A 6b58A-3zzuA:
undetectable		 6b58A-3zzuA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 9 SER A  95
ALA A 102
VAL A 119
ALA A 123
VAL A  92
 None
 1.04A 6bklA-3zzuA:
undetectable
6bklB-3zzuA:
undetectable
6bklC-3zzuA:
undetectable
6bklD-3zzuA:
undetectable		 6bklA-3zzuA:
3.39
6bklB-3zzuA:
3.39
6bklC-3zzuA:
3.39
6bklD-3zzuA:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 THR A  25
ALA A 261
LYS A 265
 None
 0.72A 6fgcA-3zzuA:
undetectable		 6fgcA-3zzuA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 THR A  25
ALA A 261
LYS A 265
 None
 0.71A 6fgdA-3zzuA:
1.9		 6fgdA-3zzuA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 SER A  65
THR A 385
THR A 326
ALA A 376
ALA A  66
 None
 1.21A 6hwdV-3zzuA:
undetectable
6hwdb-3zzuA:
undetectable		 6hwdV-3zzuA:
8.90
6hwdb-3zzuA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		5 / 12 SER A  65
THR A 385
THR A 326
ALA A 376
ALA A  66
 None
 1.21A 6hwdH-3zzuA:
undetectable
6hwdN-3zzuA:
undetectable		 6hwdH-3zzuA:
8.90
6hwdN-3zzuA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3zzu ELONGATION FACTOR G
(Staphylococcus
aureus) 		3 / 3 THR A  26
GLU A 113
ASN A 135
 None
 0.69A 6nj9K-3zzuA:
3.0		 6nj9K-3zzuA:
19.10