SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.05A 1c9sQ-4a0mA:
undetectable
1c9sR-4a0mA:
undetectable		 1c9sQ-4a0mA:
9.68
1c9sR-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 GLY A 393
GLY A 360
ALA A 349
THR A 375
ILE A 356
 None
 1.04A 1c9sL-4a0mA:
undetectable
1c9sV-4a0mA:
undetectable		 1c9sL-4a0mA:
9.68
1c9sV-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 SER A 237
LEU A 418
TYR A 416
GLY A 235
PHE A 392
 None
NAD  A1498 (-4.6A)
None
NAD  A1498 (-3.3A)
NAD  A1498 (-3.9A)
 1.44A 1fdsA-4a0mA:
3.7		 1fdsA-4a0mA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 GLY A 393
GLY A 360
ALA A 349
THR A 375
ILE A 356
 None
 1.02A 1gtfD-4a0mA:
undetectable
1gtfE-4a0mA:
undetectable		 1gtfD-4a0mA:
9.68
1gtfE-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 GLY A 393
GLY A 360
ALA A 349
THR A 375
ILE A 356
 None
 1.02A 1gtfJ-4a0mA:
undetectable
1gtfK-4a0mA:
undetectable		 1gtfJ-4a0mA:
9.68
1gtfK-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.05A 1gtfQ-4a0mA:
undetectable
1gtfR-4a0mA:
undetectable		 1gtfQ-4a0mA:
9.68
1gtfR-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.04A 1gtfR-4a0mA:
undetectable
1gtfS-4a0mA:
undetectable		 1gtfR-4a0mA:
9.68
1gtfS-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.05A 1gtfS-4a0mA:
undetectable
1gtfT-4a0mA:
undetectable		 1gtfS-4a0mA:
9.68
1gtfT-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLY A 393
GLY A 360
ALA A 349
THR A 375
ILE A 356
 None
 1.03A 1gtnL-4a0mA:
undetectable
1gtnV-4a0mA:
undetectable		 1gtnL-4a0mA:
9.68
1gtnV-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 LEU A  92
ASP A  96
ILE A  39
GLU A 193
 None
K  A1497 (-4.0A)
None
None
 1.02A 1mt1A-4a0mA:
undetectable
1mt1F-4a0mA:
undetectable		 1mt1A-4a0mA:
7.19
1mt1F-4a0mA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 LEU A  92
ASP A  96
ILE A  39
GLU A 193
 None
K  A1497 (-4.0A)
None
None
 0.90A 1n13A-4a0mA:
undetectable
1n13F-4a0mA:
undetectable		 1n13A-4a0mA:
7.19
1n13F-4a0mA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 7 LEU A  92
ASP A  96
ILE A  39
GLU A 193
 None
K  A1497 (-4.0A)
None
None
 0.90A 1n13I-4a0mA:
undetectable
1n13L-4a0mA:
undetectable		 1n13I-4a0mA:
7.19
1n13L-4a0mA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.02A 1utdL-4a0mA:
undetectable
1utdM-4a0mA:
undetectable		 1utdL-4a0mA:
9.68
1utdM-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.03A 1utdO-4a0mA:
undetectable
1utdP-4a0mA:
undetectable		 1utdO-4a0mA:
9.68
1utdP-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.00A 1utdP-4a0mA:
undetectable
1utdQ-4a0mA:
undetectable		 1utdP-4a0mA:
9.68
1utdQ-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.01A 1utdS-4a0mA:
undetectable
1utdT-4a0mA:
undetectable		 1utdS-4a0mA:
9.68
1utdT-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 GLY A 360
ALA A 349
THR A 375
ILE A 356
GLY A 393
 None
 1.04A 1utdU-4a0mA:
undetectable
1utdV-4a0mA:
undetectable		 1utdU-4a0mA:
9.68
1utdV-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 GLY A 393
GLY A 360
ALA A 349
THR A 375
ILE A 356
 None
 1.02A 1utdL-4a0mA:
undetectable
1utdV-4a0mA:
undetectable		 1utdL-4a0mA:
9.68
1utdV-4a0mA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 ILE A  39
GLU A 193
LEU A  92
ASP A  96
 None
None
None
K  A1497 (-4.0A)
 0.92A 2qqdB-4a0mA:
undetectable
2qqdC-4a0mA:
undetectable		 2qqdB-4a0mA:
12.79
2qqdC-4a0mA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 SER A 447
LEU A 256
THR A 234
ILE A 264
GLY A 440
 None
None
NAD  A1498 (-3.9A)
None
None
 1.39A 2v0mA-4a0mA:
undetectable		 2v0mA-4a0mA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 ALA A 293
VAL A 439
TRP A 456
SER A 262
GLY A 282
 None
None
NAD  A1498 (-4.4A)
None
None
 1.38A 3a65A-4a0mA:
undetectable		 3a65A-4a0mA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 ILE A  20
ARG A  24
THR A 212
LEU A 211
 None
 0.96A 3ag1N-4a0mA:
undetectable
3ag1W-4a0mA:
undetectable		 3ag1N-4a0mA:
21.12
3ag1W-4a0mA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 ASN A 445
VAL A 270
VAL A 299
THR A 279
ILE A 264
 None
 1.23A 3bf1A-4a0mA:
undetectable
3bf1B-4a0mA:
undetectable		 3bf1A-4a0mA:
19.92
3bf1B-4a0mA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 LEU A 162
VAL A 197
ILE A 169
LEU A 208
ILE A  78
 None
 0.93A 3jw3B-4a0mA:
undetectable		 3jw3B-4a0mA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 GLY A 465
VAL A 452
GLN A 453
ASN A 475
GLY A 472
 None
 1.32A 3km6A-4a0mA:
undetectable		 3km6A-4a0mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 GLY A 465
VAL A 452
GLN A 453
ASN A 475
GLY A 472
 None
 1.39A 3kmoA-4a0mA:
undetectable		 3kmoA-4a0mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 6 ILE A  82
ALA A  79
ALA A 170
THR A 166
 None
 1.00A 3mdrB-4a0mA:
undetectable		 3mdrB-4a0mA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		6 / 12 LEU A 192
ILE A 210
LEU A 173
GLY A  14
ASN A 199
ALA A  54
 None
 1.31A 3uwlB-4a0mA:
undetectable		 3uwlB-4a0mA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 ASN A 287
GLN A 289
MET A 343
GLY A 393
GLY A 369
 None
 1.42A 4a6nC-4a0mA:
undetectable		 4a6nC-4a0mA:
21.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 ASN A 159
LEU A 163
MET A 164
TRP A 167
SER A 292
 NAD  A1498 (-3.5A)
None
NAD  A1498 ( 3.9A)
None
None
 0.52A 4fr8A-4a0mA:
59.0		 4fr8A-4a0mA:
41.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY A 331
PRO A 332
GLN A 289
 None
 0.57A 4oltB-4a0mA:
undetectable		 4oltB-4a0mA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 GLY A 331
PRO A 332
GLN A 289
 None
 0.55A 4qwpB-4a0mA:
undetectable		 4qwpB-4a0mA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 PRO A 204
GLY A  14
GLY A 206
LEU A 208
LEU A 192
 None
 1.06A 5c0oH-4a0mA:
3.9		 5c0oH-4a0mA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 ASN A 159
LEU A 163
MET A 164
TRP A 167
CYH A 291
 NAD  A1498 (-3.5A)
None
NAD  A1498 ( 3.9A)
None
NAD  A1498 (-3.3A)
 0.57A 5fhzA-4a0mA:
57.5		 5fhzA-4a0mA:
41.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 VAL A 152
ASP A 229
LEU A 203
ALA A 172
PRO A 148
 None
 1.00A 5hnzB-4a0mA:
undetectable		 5hnzB-4a0mA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 VAL A 152
ASP A 229
LEU A 203
ALA A 172
PRO A 148
 None
 1.16A 5nd2B-4a0mA:
2.4		 5nd2B-4a0mA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 LEU A 192
PRO A 183
GLY A 195
LEU A  10
ARG A  17
 None
 1.35A 5o96E-4a0mA:
2.6
5o96F-4a0mA:
undetectable		 5o96E-4a0mA:
18.62
5o96F-4a0mA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 9 VAL A 197
PHE A 194
LEU A 162
ILE A 169
THR A 166
 None
 1.34A 5zsfA-4a0mA:
0.5
5zsfB-4a0mA:
0.0		 5zsfA-4a0mA:
11.85
5zsfB-4a0mA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 LEU A 192
ILE A 210
GLY A  14
ASN A 199
ALA A  54
 None
 1.15A 6qxsD-4a0mA:
undetectable		 6qxsD-4a0mA:
18.55