SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 1c9sL-4a0sA:
undetectable
1c9sM-4a0sA:
undetectable		 1c9sL-4a0sA:
10.76
1c9sM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 1c9sM-4a0sA:
undetectable
1c9sN-4a0sA:
undetectable		 1c9sM-4a0sA:
10.76
1c9sN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1c9sR-4a0sA:
undetectable
1c9sS-4a0sA:
undetectable		 1c9sR-4a0sA:
10.76
1c9sS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 1c9sS-4a0sA:
undetectable
1c9sT-4a0sA:
undetectable		 1c9sS-4a0sA:
10.76
1c9sT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 1gtfA-4a0sA:
undetectable
1gtfB-4a0sA:
undetectable		 1gtfA-4a0sA:
10.76
1gtfB-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 1gtfM-4a0sA:
undetectable
1gtfN-4a0sA:
undetectable		 1gtfM-4a0sA:
10.76
1gtfN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 8 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1gtfN-4a0sA:
undetectable
1gtfO-4a0sA:
undetectable		 1gtfN-4a0sA:
10.76
1gtfO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 1gtfO-4a0sA:
undetectable
1gtfP-4a0sA:
undetectable		 1gtfO-4a0sA:
10.76
1gtfP-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 1gtfP-4a0sA:
undetectable
1gtfQ-4a0sA:
undetectable		 1gtfP-4a0sA:
10.76
1gtfQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.28A 1gtfT-4a0sA:
undetectable
1gtfU-4a0sA:
undetectable		 1gtfT-4a0sA:
10.76
1gtfU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 1gtfU-4a0sA:
undetectable
1gtfV-4a0sA:
undetectable		 1gtfU-4a0sA:
10.76
1gtfV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 1gtfL-4a0sA:
undetectable
1gtfV-4a0sA:
undetectable		 1gtfL-4a0sA:
10.76
1gtfV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.23A 1gtnG-4a0sA:
undetectable
1gtnH-4a0sA:
undetectable		 1gtnG-4a0sA:
10.76
1gtnH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1gtnL-4a0sA:
undetectable
1gtnM-4a0sA:
undetectable		 1gtnL-4a0sA:
10.76
1gtnM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 1gtnN-4a0sA:
undetectable
1gtnO-4a0sA:
undetectable		 1gtnN-4a0sA:
10.76
1gtnO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 1gtnO-4a0sA:
undetectable
1gtnP-4a0sA:
undetectable		 1gtnO-4a0sA:
10.76
1gtnP-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1gtnQ-4a0sA:
undetectable
1gtnR-4a0sA:
undetectable		 1gtnQ-4a0sA:
10.76
1gtnR-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.34A 1gtnR-4a0sA:
undetectable
1gtnS-4a0sA:
undetectable		 1gtnR-4a0sA:
10.76
1gtnS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1gtnS-4a0sA:
undetectable
1gtnT-4a0sA:
undetectable		 1gtnS-4a0sA:
10.76
1gtnT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 SER A  72
SER A  73
ILE A  74
GLU A 194
 None
 0.91A 1meiA-4a0sA:
undetectable		 1meiA-4a0sA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 PRO A 382
MET A 384
ALA A 410
GLU A 194
 None
 1.03A 1qhyA-4a0sA:
undetectable		 1qhyA-4a0sA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 4 SER A 235
ILE A 238
VAL A 252
THR A 318
 None
None
NAP  A1447 (-3.8A)
None
 1.20A 1u70A-4a0sA:
2.2		 1u70A-4a0sA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 1utdM-4a0sA:
undetectable
1utdN-4a0sA:
undetectable		 1utdM-4a0sA:
10.76
1utdN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.28A 1utdN-4a0sA:
undetectable
1utdO-4a0sA:
undetectable		 1utdN-4a0sA:
10.76
1utdO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 1utdR-4a0sA:
undetectable
1utdS-4a0sA:
undetectable		 1utdR-4a0sA:
10.76
1utdS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ALA A 163
LEU A 201
SER A  72
SER A  73
ILE A  74
 CO8  A1446 ( 3.7A)
CO8  A1446 ( 4.2A)
None
None
None
 1.13A 2bl9A-4a0sA:
undetectable		 2bl9A-4a0sA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 HIS A 143
ASN A  96
GLN A  99
PRO A  62
 None
 1.32A 2ez7A-4a0sA:
undetectable		 2ez7A-4a0sA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 LEU A 275
GLY A 320
PHE A 319
VAL A 325
ALA A 296
 None
 1.34A 2kceA-4a0sA:
undetectable		 2kceA-4a0sA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 GLU A 312
MET A 209
PHE A 311
ILE A 309
 None
 0.96A 2w98B-4a0sA:
28.3		 2w98B-4a0sA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		3 / 3 MET A 352
VAL A 332
GLU A 306
 None
 0.90A 2x9gA-4a0sA:
9.6		 2x9gA-4a0sA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 7 ARG A 286
VAL A 288
ARG A 293
ILE A 324
 None
 1.08A 2yfbA-4a0sA:
undetectable		 2yfbA-4a0sA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 VAL A 288
VAL A 289
PHE A 319
ARG A 286
 None
 1.07A 3bjwF-4a0sA:
undetectable		 3bjwF-4a0sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 VAL A  65
GLY A 165
ARG A 162
LEU A  93
 None
 1.04A 3bjwE-4a0sA:
undetectable		 3bjwE-4a0sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 VAL A 288
VAL A 289
GLY A 292
ARG A 286
 None
 0.88A 3bjwA-4a0sA:
undetectable		 3bjwA-4a0sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 THR A 344
VAL A 325
LEU A 295
ILE A 324
THR A 291
 None
 1.38A 3elzC-4a0sA:
undetectable		 3elzC-4a0sA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		3 / 3 ALA A 386
VAL A 387
GLN A 418
 None
 0.51A 3of4B-4a0sA:
undetectable		 3of4B-4a0sA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 7 VAL A 112
GLY A 165
VAL A  67
VAL A  69
 None
 0.64A 3ufnB-4a0sA:
undetectable		 3ufnB-4a0sA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 HIS A 143
VAL A 139
ASP A  63
ARG A 105
 None
 0.95A 3uy4A-4a0sA:
4.5		 3uy4A-4a0sA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 5 THR A 318
GLU A 312
ARG A 272
HIS A 313
 None
None
NAP  A1447 (-3.8A)
NAP  A1447 (-4.3A)
 1.44A 4hvcB-4a0sA:
2.4		 4hvcB-4a0sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 5 VAL A 211
LEU A 374
VAL A 380
PHE A 240
 None
 0.88A 4lb0B-4a0sA:
undetectable		 4lb0B-4a0sA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 PRO A 382
SER A 199
VAL A 198
GLY A 378
 None
 0.98A 4mk4A-4a0sA:
undetectable		 4mk4A-4a0sA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 LEU A 184
GLY A 119
VAL A 179
VAL A  65
LEU A  60
 None
 1.15A 4qd3A-4a0sA:
undetectable		 4qd3A-4a0sA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ALA A 260
SER A 230
GLY A 407
GLN A 405
GLY A 441
 None
NAP  A1447 (-3.6A)
None
NAP  A1447 (-3.5A)
None
 1.06A 4r29A-4a0sA:
undetectable		 4r29A-4a0sA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ALA A 260
SER A 230
GLY A 407
GLN A 405
GLY A 441
 None
NAP  A1447 (-3.6A)
None
NAP  A1447 (-3.5A)
None
 1.07A 4r29D-4a0sA:
undetectable		 4r29D-4a0sA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 SER A 322
LEU A 275
GLY A 292
VAL A 299
LEU A 225
 None
 1.07A 4y8wA-4a0sA:
undetectable		 4y8wA-4a0sA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 SER A 322
LEU A 275
GLY A 292
VAL A 299
LEU A 225
 None
 1.07A 4y8wB-4a0sA:
undetectable		 4y8wB-4a0sA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ALA A 444
THR A 445
GLY A 231
SER A 230
ALA A 260
 None
None
NAP  A1447 (-3.3A)
NAP  A1447 (-3.6A)
None
 1.16A 4ypmA-4a0sA:
undetectable		 4ypmA-4a0sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ALA A 444
THR A 445
GLY A 407
SER A 230
ALA A 260
 None
None
None
NAP  A1447 (-3.6A)
None
 1.09A 4ypmA-4a0sA:
undetectable		 4ypmA-4a0sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eeuC-4a0sA:
undetectable
5eeuD-4a0sA:
undetectable		 5eeuC-4a0sA:
10.76
5eeuD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.23A 5eeuG-4a0sA:
undetectable
5eeuH-4a0sA:
undetectable		 5eeuG-4a0sA:
10.76
5eeuH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.29A 5eeuL-4a0sA:
undetectable
5eeuV-4a0sA:
undetectable		 5eeuL-4a0sA:
10.76
5eeuV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eeuL-4a0sA:
undetectable
5eeuM-4a0sA:
undetectable		 5eeuL-4a0sA:
10.76
5eeuM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.30A 5eeuM-4a0sA:
undetectable
5eeuN-4a0sA:
undetectable		 5eeuM-4a0sA:
10.76
5eeuN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eeuN-4a0sA:
undetectable
5eeuO-4a0sA:
undetectable		 5eeuN-4a0sA:
10.76
5eeuO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eeuP-4a0sA:
undetectable
5eeuQ-4a0sA:
undetectable		 5eeuP-4a0sA:
10.76
5eeuQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.28A 5eeuR-4a0sA:
undetectable
5eeuS-4a0sA:
undetectable		 5eeuR-4a0sA:
10.76
5eeuS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eeuS-4a0sA:
undetectable
5eeuT-4a0sA:
undetectable		 5eeuS-4a0sA:
10.76
5eeuT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eeuT-4a0sA:
undetectable
5eeuU-4a0sA:
undetectable		 5eeuT-4a0sA:
10.76
5eeuU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.28A 5eeuU-4a0sA:
undetectable
5eeuV-4a0sA:
undetectable		 5eeuU-4a0sA:
10.76
5eeuV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eevC-4a0sA:
undetectable
5eevD-4a0sA:
undetectable		 5eevC-4a0sA:
10.76
5eevD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5eevG-4a0sA:
undetectable
5eevH-4a0sA:
undetectable		 5eevG-4a0sA:
10.76
5eevH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 SER A 322
GLY A 228
HIS A 313
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
NAP  A1447 (-4.6A)
 0.94A 5eevL-4a0sA:
undetectable
5eevV-4a0sA:
undetectable		 5eevL-4a0sA:
10.76
5eevV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eevL-4a0sA:
undetectable
5eevM-4a0sA:
undetectable		 5eevL-4a0sA:
10.76
5eevM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eevM-4a0sA:
undetectable
5eevN-4a0sA:
undetectable		 5eevM-4a0sA:
10.76
5eevN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eevN-4a0sA:
undetectable
5eevO-4a0sA:
undetectable		 5eevN-4a0sA:
10.76
5eevO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eevP-4a0sA:
undetectable
5eevQ-4a0sA:
undetectable		 5eevP-4a0sA:
10.76
5eevQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eevR-4a0sA:
undetectable
5eevS-4a0sA:
undetectable		 5eevR-4a0sA:
10.76
5eevS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eevS-4a0sA:
undetectable
5eevT-4a0sA:
undetectable		 5eevS-4a0sA:
10.76
5eevT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eevT-4a0sA:
undetectable
5eevU-4a0sA:
undetectable		 5eevT-4a0sA:
10.76
5eevU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eevU-4a0sA:
undetectable
5eevV-4a0sA:
undetectable		 5eevU-4a0sA:
10.76
5eevV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eewC-4a0sA:
undetectable
5eewD-4a0sA:
undetectable		 5eewC-4a0sA:
10.76
5eewD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5eewG-4a0sA:
undetectable
5eewH-4a0sA:
undetectable		 5eewG-4a0sA:
10.76
5eewH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 SER A 322
GLY A 228
HIS A 313
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
NAP  A1447 (-4.6A)
 0.94A 5eewL-4a0sA:
undetectable
5eewV-4a0sA:
undetectable		 5eewL-4a0sA:
10.76
5eewV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eewL-4a0sA:
undetectable
5eewM-4a0sA:
undetectable		 5eewL-4a0sA:
10.76
5eewM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eewM-4a0sA:
undetectable
5eewN-4a0sA:
undetectable		 5eewM-4a0sA:
10.76
5eewN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eewN-4a0sA:
undetectable
5eewO-4a0sA:
undetectable		 5eewN-4a0sA:
10.76
5eewO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eewP-4a0sA:
undetectable
5eewQ-4a0sA:
undetectable		 5eewP-4a0sA:
10.76
5eewQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eewR-4a0sA:
undetectable
5eewS-4a0sA:
undetectable		 5eewR-4a0sA:
10.76
5eewS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eewS-4a0sA:
undetectable
5eewT-4a0sA:
undetectable		 5eewS-4a0sA:
10.76
5eewT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eewT-4a0sA:
undetectable
5eewU-4a0sA:
undetectable		 5eewT-4a0sA:
10.76
5eewU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eewU-4a0sA:
undetectable
5eewV-4a0sA:
undetectable		 5eewU-4a0sA:
10.76
5eewV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eexC-4a0sA:
undetectable
5eexD-4a0sA:
undetectable		 5eexC-4a0sA:
10.76
5eexD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5eexG-4a0sA:
undetectable
5eexH-4a0sA:
undetectable		 5eexG-4a0sA:
10.76
5eexH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5eexI-4a0sA:
undetectable
5eexJ-4a0sA:
undetectable		 5eexI-4a0sA:
10.76
5eexJ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.27A 5eexA-4a0sA:
undetectable
5eexK-4a0sA:
undetectable		 5eexA-4a0sA:
10.76
5eexK-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5eexL-4a0sA:
undetectable
5eexV-4a0sA:
undetectable		 5eexL-4a0sA:
10.76
5eexV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eexL-4a0sA:
undetectable
5eexM-4a0sA:
undetectable		 5eexL-4a0sA:
10.76
5eexM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eexM-4a0sA:
undetectable
5eexN-4a0sA:
undetectable		 5eexM-4a0sA:
10.76
5eexN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eexN-4a0sA:
undetectable
5eexO-4a0sA:
undetectable		 5eexN-4a0sA:
10.76
5eexO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eexP-4a0sA:
undetectable
5eexQ-4a0sA:
undetectable		 5eexP-4a0sA:
10.76
5eexQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eexR-4a0sA:
undetectable
5eexS-4a0sA:
undetectable		 5eexR-4a0sA:
10.76
5eexS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eexS-4a0sA:
undetectable
5eexT-4a0sA:
undetectable		 5eexS-4a0sA:
10.76
5eexT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eexT-4a0sA:
undetectable
5eexU-4a0sA:
undetectable		 5eexT-4a0sA:
10.76
5eexU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eexU-4a0sA:
undetectable
5eexV-4a0sA:
undetectable		 5eexU-4a0sA:
10.76
5eexV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eeyC-4a0sA:
undetectable
5eeyD-4a0sA:
undetectable		 5eeyC-4a0sA:
10.76
5eeyD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5eeyG-4a0sA:
undetectable
5eeyH-4a0sA:
undetectable		 5eeyG-4a0sA:
10.76
5eeyH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5eeyI-4a0sA:
undetectable
5eeyJ-4a0sA:
undetectable		 5eeyI-4a0sA:
10.76
5eeyJ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5eeyL-4a0sA:
undetectable
5eeyV-4a0sA:
undetectable		 5eeyL-4a0sA:
10.76
5eeyV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eeyL-4a0sA:
undetectable
5eeyM-4a0sA:
undetectable		 5eeyL-4a0sA:
10.76
5eeyM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eeyM-4a0sA:
undetectable
5eeyN-4a0sA:
undetectable		 5eeyM-4a0sA:
10.76
5eeyN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eeyN-4a0sA:
undetectable
5eeyO-4a0sA:
undetectable		 5eeyN-4a0sA:
10.76
5eeyO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eeyP-4a0sA:
undetectable
5eeyQ-4a0sA:
undetectable		 5eeyP-4a0sA:
10.76
5eeyQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eeyR-4a0sA:
undetectable
5eeyS-4a0sA:
undetectable		 5eeyR-4a0sA:
10.76
5eeyS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eeyS-4a0sA:
undetectable
5eeyT-4a0sA:
undetectable		 5eeyS-4a0sA:
10.76
5eeyT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eeyT-4a0sA:
undetectable
5eeyU-4a0sA:
undetectable		 5eeyT-4a0sA:
10.76
5eeyU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eeyU-4a0sA:
undetectable
5eeyV-4a0sA:
undetectable		 5eeyU-4a0sA:
10.76
5eeyV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5eezC-4a0sA:
undetectable
5eezD-4a0sA:
undetectable		 5eezC-4a0sA:
10.76
5eezD-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5eezG-4a0sA:
undetectable
5eezH-4a0sA:
undetectable		 5eezG-4a0sA:
10.76
5eezH-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5eezI-4a0sA:
undetectable
5eezJ-4a0sA:
undetectable		 5eezI-4a0sA:
10.76
5eezJ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 8 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5eezL-4a0sA:
undetectable
5eezV-4a0sA:
undetectable		 5eezL-4a0sA:
10.76
5eezV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eezL-4a0sA:
undetectable
5eezM-4a0sA:
undetectable		 5eezL-4a0sA:
10.76
5eezM-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eezM-4a0sA:
undetectable
5eezN-4a0sA:
undetectable		 5eezM-4a0sA:
10.76
5eezN-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5eezN-4a0sA:
undetectable
5eezO-4a0sA:
undetectable		 5eezN-4a0sA:
10.76
5eezO-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eezP-4a0sA:
undetectable
5eezQ-4a0sA:
undetectable		 5eezP-4a0sA:
10.76
5eezQ-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eezR-4a0sA:
undetectable
5eezS-4a0sA:
undetectable		 5eezR-4a0sA:
10.76
5eezS-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5eezS-4a0sA:
undetectable
5eezT-4a0sA:
undetectable		 5eezS-4a0sA:
10.76
5eezT-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5eezT-4a0sA:
undetectable
5eezU-4a0sA:
undetectable		 5eezT-4a0sA:
10.76
5eezU-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5eezU-4a0sA:
undetectable
5eezV-4a0sA:
undetectable		 5eezU-4a0sA:
10.76
5eezV-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5ef0C-4a0sA:
undetectable
5ef0D-4a0sA:
undetectable		 5ef0C-4a0sA:
10.76
5ef0D-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5ef0G-4a0sA:
undetectable
5ef0H-4a0sA:
undetectable		 5ef0G-4a0sA:
10.76
5ef0H-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5ef0I-4a0sA:
undetectable
5ef0J-4a0sA:
undetectable		 5ef0I-4a0sA:
10.76
5ef0J-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.27A 5ef0A-4a0sA:
undetectable
5ef0K-4a0sA:
undetectable		 5ef0A-4a0sA:
10.76
5ef0K-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5ef0L-4a0sA:
undetectable
5ef0V-4a0sA:
undetectable		 5ef0L-4a0sA:
10.76
5ef0V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef0L-4a0sA:
undetectable
5ef0M-4a0sA:
undetectable		 5ef0L-4a0sA:
10.76
5ef0M-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef0M-4a0sA:
undetectable
5ef0N-4a0sA:
undetectable		 5ef0M-4a0sA:
10.76
5ef0N-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef0N-4a0sA:
undetectable
5ef0O-4a0sA:
undetectable		 5ef0N-4a0sA:
10.76
5ef0O-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef0P-4a0sA:
undetectable
5ef0Q-4a0sA:
undetectable		 5ef0P-4a0sA:
10.76
5ef0Q-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef0R-4a0sA:
undetectable
5ef0S-4a0sA:
undetectable		 5ef0R-4a0sA:
10.76
5ef0S-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef0S-4a0sA:
undetectable
5ef0T-4a0sA:
undetectable		 5ef0S-4a0sA:
10.76
5ef0T-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef0T-4a0sA:
undetectable
5ef0U-4a0sA:
undetectable		 5ef0T-4a0sA:
10.76
5ef0U-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef0U-4a0sA:
undetectable
5ef0V-4a0sA:
undetectable		 5ef0U-4a0sA:
10.76
5ef0V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5ef1C-4a0sA:
undetectable
5ef1D-4a0sA:
undetectable		 5ef1C-4a0sA:
10.76
5ef1D-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5ef1G-4a0sA:
undetectable
5ef1H-4a0sA:
undetectable		 5ef1G-4a0sA:
10.76
5ef1H-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5ef1I-4a0sA:
undetectable
5ef1J-4a0sA:
undetectable		 5ef1I-4a0sA:
10.76
5ef1J-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 8 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5ef1L-4a0sA:
undetectable
5ef1V-4a0sA:
undetectable		 5ef1L-4a0sA:
10.76
5ef1V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef1L-4a0sA:
undetectable
5ef1M-4a0sA:
undetectable		 5ef1L-4a0sA:
10.76
5ef1M-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef1M-4a0sA:
undetectable
5ef1N-4a0sA:
undetectable		 5ef1M-4a0sA:
10.76
5ef1N-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef1N-4a0sA:
undetectable
5ef1O-4a0sA:
undetectable		 5ef1N-4a0sA:
10.76
5ef1O-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef1P-4a0sA:
undetectable
5ef1Q-4a0sA:
undetectable		 5ef1P-4a0sA:
10.76
5ef1Q-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef1R-4a0sA:
undetectable
5ef1S-4a0sA:
undetectable		 5ef1R-4a0sA:
10.76
5ef1S-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef1S-4a0sA:
undetectable
5ef1T-4a0sA:
undetectable		 5ef1S-4a0sA:
10.76
5ef1T-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef1T-4a0sA:
undetectable
5ef1U-4a0sA:
undetectable		 5ef1T-4a0sA:
10.76
5ef1U-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef1U-4a0sA:
undetectable
5ef1V-4a0sA:
undetectable		 5ef1U-4a0sA:
10.76
5ef1V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5ef2C-4a0sA:
undetectable
5ef2D-4a0sA:
undetectable		 5ef2C-4a0sA:
10.76
5ef2D-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5ef2G-4a0sA:
undetectable
5ef2H-4a0sA:
undetectable		 5ef2G-4a0sA:
10.76
5ef2H-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5ef2I-4a0sA:
undetectable
5ef2J-4a0sA:
undetectable		 5ef2I-4a0sA:
10.76
5ef2J-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 8 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.30A 5ef2L-4a0sA:
undetectable
5ef2V-4a0sA:
undetectable		 5ef2L-4a0sA:
10.76
5ef2V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef2L-4a0sA:
undetectable
5ef2M-4a0sA:
undetectable		 5ef2L-4a0sA:
10.76
5ef2M-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef2M-4a0sA:
undetectable
5ef2N-4a0sA:
undetectable		 5ef2M-4a0sA:
10.76
5ef2N-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef2N-4a0sA:
undetectable
5ef2O-4a0sA:
undetectable		 5ef2N-4a0sA:
10.76
5ef2O-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef2P-4a0sA:
undetectable
5ef2Q-4a0sA:
undetectable		 5ef2P-4a0sA:
10.76
5ef2Q-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef2R-4a0sA:
undetectable
5ef2S-4a0sA:
undetectable		 5ef2R-4a0sA:
10.76
5ef2S-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef2S-4a0sA:
undetectable
5ef2T-4a0sA:
undetectable		 5ef2S-4a0sA:
10.76
5ef2T-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef2T-4a0sA:
undetectable
5ef2U-4a0sA:
undetectable		 5ef2T-4a0sA:
10.76
5ef2U-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef2U-4a0sA:
undetectable
5ef2V-4a0sA:
undetectable		 5ef2U-4a0sA:
10.76
5ef2V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.27A 5ef3C-4a0sA:
undetectable
5ef3D-4a0sA:
undetectable		 5ef3C-4a0sA:
10.76
5ef3D-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.24A 5ef3G-4a0sA:
undetectable
5ef3H-4a0sA:
undetectable		 5ef3G-4a0sA:
10.76
5ef3H-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 11 SER A 322
GLY A 228
HIS A 313
THR A 318
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
 1.26A 5ef3I-4a0sA:
undetectable
5ef3J-4a0sA:
undetectable		 5ef3I-4a0sA:
10.76
5ef3J-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.27A 5ef3A-4a0sA:
undetectable
5ef3K-4a0sA:
undetectable		 5ef3A-4a0sA:
10.76
5ef3K-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 SER A 322
GLY A 228
HIS A 313
THR A 314
 None
NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
NAP  A1447 (-4.6A)
 0.94A 5ef3L-4a0sA:
undetectable
5ef3V-4a0sA:
undetectable		 5ef3L-4a0sA:
10.76
5ef3V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef3L-4a0sA:
undetectable
5ef3M-4a0sA:
undetectable		 5ef3L-4a0sA:
10.76
5ef3M-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef3M-4a0sA:
undetectable
5ef3N-4a0sA:
undetectable		 5ef3M-4a0sA:
10.76
5ef3N-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.33A 5ef3N-4a0sA:
undetectable
5ef3O-4a0sA:
undetectable		 5ef3N-4a0sA:
10.76
5ef3O-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef3P-4a0sA:
undetectable
5ef3Q-4a0sA:
undetectable		 5ef3P-4a0sA:
10.76
5ef3Q-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef3R-4a0sA:
undetectable
5ef3S-4a0sA:
undetectable		 5ef3R-4a0sA:
10.76
5ef3S-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.32A 5ef3S-4a0sA:
undetectable
5ef3T-4a0sA:
undetectable		 5ef3S-4a0sA:
10.76
5ef3T-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.31A 5ef3T-4a0sA:
undetectable
5ef3U-4a0sA:
undetectable		 5ef3T-4a0sA:
10.76
5ef3U-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 228
HIS A 313
THR A 318
THR A 314
SER A 322
 NAP  A1447 (-3.2A)
NAP  A1447 (-4.3A)
None
NAP  A1447 (-4.6A)
None
 1.29A 5ef3U-4a0sA:
undetectable
5ef3V-4a0sA:
undetectable		 5ef3U-4a0sA:
10.76
5ef3V-4a0sA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 8 GLN A  99
ARG A 105
GLY A 100
ASN A  96
 None
 1.02A 5hwaA-4a0sA:
undetectable		 5hwaA-4a0sA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 6 PRO A 248
VAL A 269
VAL A 252
ILE A 238
 None
None
NAP  A1447 (-3.8A)
None
 0.90A 5pbeA-4a0sA:
undetectable		 5pbeA-4a0sA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 VAL A 406
GLY A 407
ALA A 260
SER A 385
ASN A 437
 None
 0.92A 5x6yB-4a0sA:
undetectable		 5x6yB-4a0sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 LEU A 390
GLY A 114
ALA A 174
PRO A 141
PHE A 166
 None
None
None
CO8  A1446 ( 4.4A)
CO8  A1446 (-4.2A)
 1.25A 5x6yC-4a0sA:
2.5		 5x6yC-4a0sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 ASP A 135
ALA A   6
ILE A  16
GLY A 119
GLY A  10
 None
 1.30A 6awoA-4a0sA:
undetectable		 6awoA-4a0sA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 ASP A 135
ALA A   6
ILE A  16
GLY A 119
GLY A  10
 None
 1.30A 6awqA-4a0sA:
undetectable		 6awqA-4a0sA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 ILE A 238
LEU A 225
VAL A 251
LEU A 264
LEU A 439
 None
 1.05A 6b54A-4a0sA:
undetectable		 6b54A-4a0sA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		3 / 3 GLY A 336
THR A 334
GLU A 312
 NAP  A1447 ( 4.1A)
None
None
 0.46A 6b58A-4a0sA:
2.8		 6b58A-4a0sA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 9 ALA A 260
VAL A 252
ALA A 229
SER A 230
VAL A 269
 None
NAP  A1447 (-3.8A)
None
NAP  A1447 (-3.6A)
None
 1.26A 6bklA-4a0sA:
undetectable
6bklB-4a0sA:
undetectable
6bklC-4a0sA:
undetectable
6bklD-4a0sA:
undetectable		 6bklA-4a0sA:
4.81
6bklB-4a0sA:
4.81
6bklC-4a0sA:
4.81
6bklD-4a0sA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 114
GLY A 165
SER A  72
THR A  78
ILE A  74
 None
 1.19A 6exiA-4a0sA:
8.2		 6exiA-4a0sA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 GLY A 114
GLY A 165
SER A  72
THR A  78
ILE A  74
 None
 1.19A 6exiB-4a0sA:
8.1		 6exiB-4a0sA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 GLY A 114
GLY A 165
SER A  72
THR A  78
ILE A  74
 None
 1.20A 6exiC-4a0sA:
8.4
6exiD-4a0sA:
8.5		 6exiC-4a0sA:
11.56
6exiD-4a0sA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 12 GLY A 114
GLY A 165
SER A  72
THR A  78
ILE A  74
 None
 1.20A 6exiC-4a0sA:
8.5
6exiD-4a0sA:
8.5		 6exiC-4a0sA:
11.56
6exiD-4a0sA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		5 / 10 TYR A 388
VAL A 409
GLY A 407
SER A 230
ALA A 229
 None
None
None
NAP  A1447 (-3.6A)
None
 1.48A 6hu9L-4a0sA:
undetectable
6hu9P-4a0sA:
undetectable
6hu9T-4a0sA:
undetectable		 6hu9L-4a0sA:
21.71
6hu9P-4a0sA:
19.24
6hu9T-4a0sA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_1
(UNCHARACTERIZED
PROTEIN)		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 4 THR A 318
GLU A 312
ARG A 272
HIS A 313
 None
None
NAP  A1447 (-3.8A)
NAP  A1447 (-4.3A)
 1.35A 6mn8A-4a0sA:
undetectable		 6mn8A-4a0sA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E
(Streptomyces
cinnabarigriseus) 		4 / 7 TYR A  25
HIS A 111
ASN A 169
GLY A 177
 None
 0.84A 6n7fA-4a0sA:
3.2		 6n7fA-4a0sA:
11.19