SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IBG_H_OBNH1_2 (IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN) IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN))	4a0u	TAIL FIBER PROTEIN (Escherichia virus T7)	4 / 7	THR A 418 HIS A 411 TYR A 385 LEU A 387	None	1.08A	1ibgL-4a0uA: undetectable	1ibgL-4a0uA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_A_ADNA501_1 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	4a0u	TAIL FIBER PROTEIN (Escherichia virus T7)	5 / 12	VAL A 473 SER A 483 PHE A 535 GLY A 534 GLN A 527	None	1.07A	4pevA-4a0uA: undetectable	4pevA-4a0uA: 19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CDN_G_EVPG2101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B)	4a0u	TAIL FIBER PROTEIN (Escherichia virus T7)	4 / 6	GLY A 513 ASP A 512 ARG A 491 GLY A 510	None	0.88A	5cdnA-4a0uA: undetectable 5cdnB-4a0uA: undetectable	5cdnA-4a0uA: 17.21 5cdnB-4a0uA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FCT_B_C2FB402_1 (THYMIDYLATE SYNTHASE)	4a0u	TAIL FIBER PROTEIN (Escherichia virus T7)	3 / 3	ASN A 546 ASP A 520 GLY A 521	None	0.45A	5fctB-4a0uA: undetectable	5fctB-4a0uA: 22.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IBG_H_OBNH1_2","IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN);IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN)","4a0u","TAIL FIBER PROTEIN","Escherichia virus T7",4,"THR A 418;HIS A 411;TYR A 385;LEU A 387","None","1.08A","1ibgL-4a0uA:undetectable","1ibgL-4a0uA:20.70"],["4PEV_A_ADNA501_1","MEMBRANE LIPOPROTEIN FAMILY PROTEIN","4a0u","TAIL FIBER PROTEIN","Escherichia virus T7",5,"VAL A 473;SER A 483;PHE A 535;GLY A 534;GLN A 527","None","1.07A","4pevA-4a0uA:undetectable","4pevA-4a0uA:19.48"],["5CDN_G_EVPG2101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","4a0u","TAIL FIBER PROTEIN","Escherichia virus T7",4,"GLY A 513;ASP A 512;ARG A 491;GLY A 510","None","0.88A","5cdnA-4a0uA:undetectable;5cdnB-4a0uA:undetectable","5cdnA-4a0uA:17.21;5cdnB-4a0uA:19.83"],["5FCT_B_C2FB402_1","THYMIDYLATE SYNTHASE","4a0u","TAIL FIBER PROTEIN","Escherichia virus T7",3,"ASN A 546;ASP A 520;GLY A 521","None","0.45A","5fctB-4a0uA:undetectable","5fctB-4a0uA:22.15"]]