SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXK_A_IMNA2001_1 (SERUM ALBUMIN)	4a0x	TRANSCRIPTION FACTOR FAPR (Staphylococcus aureus)	4 / 8	SER A 136 ALA A 154 ARG A 155 LEU A 125	None	1.08A	2bxkA-4a0xA: undetectable	2bxkA-4a0xA: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G78_A_REAA200_1 (CELLULAR RETINOIC ACID-BINDING PROTEIN 2)	4a0x	TRANSCRIPTION FACTOR FAPR (Staphylococcus aureus)	5 / 12	LEU A 114 ILE A 108 ALA A 109 VAL A 150 ARG A 56	None	1.03A	2g78A-4a0xA: 2.9	2g78A-4a0xA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A99_D_MIYD392_1 (TETX2 PROTEIN)	4a0x	TRANSCRIPTION FACTOR FAPR (Staphylococcus aureus)	4 / 5	HIS A 30 SER A 33 SER A 39 VAL A 38	ZN A 205 (-3.6A) None None None	1.47A	4a99D-4a0xA: undetectable	4a99D-4a0xA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUH_A_ACTA610_0 (SERUM ALBUMIN)	4a0x	TRANSCRIPTION FACTOR FAPR (Staphylococcus aureus)	3 / 3	VAL A 38 SER A 39 THR A 42	None	0.43A	4luhA-4a0xA: 2.2	4luhA-4a0xA: 15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EF6_A_ACTA405_0 (AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	4a0x	TRANSCRIPTION FACTOR FAPR (Staphylococcus aureus)	4 / 6	ARG A 18 PRO A 25 ARG A 58 ILE A 52	None	1.47A	6ef6A-4a0xA: undetectable	6ef6A-4a0xA: 16.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXK_A_IMNA2001_1","SERUM ALBUMIN","4a0x","TRANSCRIPTION FACTOR FAPR","Staphylococcus aureus",4,"SER A 136;ALA A 154;ARG A 155;LEU A 125","None","1.08A","2bxkA-4a0xA:undetectable","2bxkA-4a0xA:16.35"],["2G78_A_REAA200_1","CELLULAR RETINOIC ACID-BINDING PROTEIN 2","4a0x","TRANSCRIPTION FACTOR FAPR","Staphylococcus aureus",5,"LEU A 114;ILE A 108;ALA A 109;VAL A 150;ARG A  56","None","1.03A","2g78A-4a0xA:2.9","2g78A-4a0xA:18.95"],["4A99_D_MIYD392_1","TETX2 PROTEIN","4a0x","TRANSCRIPTION FACTOR FAPR","Staphylococcus aureus",4,"HIS A  30;SER A  33;SER A  39;VAL A  38"," ZN A 205 (-3.6A);None;None;None","1.47A","4a99D-4a0xA:undetectable","4a99D-4a0xA:19.90"],["4LUH_A_ACTA610_0","SERUM ALBUMIN","4a0x","TRANSCRIPTION FACTOR FAPR","Staphylococcus aureus",3,"VAL A  38;SER A  39;THR A  42","None","0.43A","4luhA-4a0xA:2.2","4luhA-4a0xA:15.42"],["6EF6_A_ACTA405_0","AMINOGLYCOSIDE PHOSPHOTRANSFERASE","4a0x","TRANSCRIPTION FACTOR FAPR","Staphylococcus aureus",4,"ARG A  18;PRO A  25;ARG A  58;ILE A  52","None","1.47A","6ef6A-4a0xA:undetectable","6ef6A-4a0xA:16.71"]]