SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.84A 1a7yA-4a1rA:
undetectable		 1a7yA-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.82A 1dscC-4a1rA:
undetectable		 1dscC-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4a1r LIP
(Serratia
marcescens) 		4 / 8 ILE A 135
HIS A 161
LEU A  39
VAL A 121
 None
 0.79A 1fslB-4a1rA:
undetectable		 1fslB-4a1rA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.85A 1i3wE-4a1rA:
undetectable		 1i3wE-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.83A 1i3wE-4a1rA:
undetectable		 1i3wE-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.85A 1i3wF-4a1rA:
undetectable		 1i3wF-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.87A 1i3wG-4a1rA:
undetectable		 1i3wG-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.86A 1i3wG-4a1rA:
undetectable		 1i3wG-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.84A 1i3wH-4a1rA:
undetectable		 1i3wH-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.83A 1mnvD-4a1rA:
undetectable		 1mnvD-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.81A 1mnvD-4a1rA:
undetectable		 1mnvD-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.86A 1ovfB-4a1rA:
undetectable		 1ovfB-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.83A 1qfiA-4a1rA:
undetectable		 1qfiA-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.86A 1qfiB-4a1rA:
undetectable		 1qfiB-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.85A 1unjL-4a1rA:
undetectable		 1unjL-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.82A 1unjL-4a1rA:
undetectable		 1unjL-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.86A 1unjR-4a1rA:
undetectable		 1unjR-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.84A 1unjR-4a1rA:
undetectable		 1unjR-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.78A 1unjW-4a1rA:
undetectable		 1unjW-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.84A 1unjX-4a1rA:
undetectable		 1unjX-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.82A 1unjX-4a1rA:
undetectable		 1unjX-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.81A 1unmE-4a1rA:
undetectable		 1unmE-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.78A 1unmE-4a1rA:
undetectable		 1unmE-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 143
THR A 145
PRO A 142
 None
 0.84A 1unmF-4a1rA:
undetectable		 1unmF-4a1rA:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 4a1r LIP
(Serratia
marcescens) 		5 / 10 ILE A 122
PHE A  77
LEU A  63
LEU A  87
VAL A  86
 None
 1.15A 3o02A-4a1rA:
undetectable
3o02B-4a1rA:
undetectable		 3o02A-4a1rA:
21.43
3o02B-4a1rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 PRO A  34
ASP A 156
GLU A 157
 None
 0.86A 3v4tC-4a1rA:
undetectable		 3v4tC-4a1rA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4a1r LIP
(Serratia
marcescens) 		4 / 5 PHE A  41
LEU A 137
GLY A 120
ILE A  60
 None
 0.86A 3wrkA-4a1rA:
undetectable		 3wrkA-4a1rA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4a1r LIP
(Serratia
marcescens) 		3 / 3 THR A 145
PRO A 142
THR A 143
 None
 0.87A 4hivD-4a1rA:
undetectable		 4hivD-4a1rA:
5.76