SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4a20 UBIQUITIN-LIKE
PROTEIN MDY2
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 132
ASP A  96
SER A  93
HIS A  90
 None
 1.31A 4aq7A-4a20A:
2.7		 4aq7A-4a20A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4a20 UBIQUITIN-LIKE
PROTEIN MDY2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  99
ASP A 128
LEU A 119
LEU A 105
ILE A 106
 None
SO4  A1152 (-3.4A)
None
None
None
 0.98A 4odrA-4a20A:
undetectable
4odrB-4a20A:
undetectable		 4odrA-4a20A:
17.76
4odrB-4a20A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4a20 UBIQUITIN-LIKE
PROTEIN MDY2
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  99
ASP A 128
LEU A 119
LEU A 105
ILE A 106
 None
SO4  A1152 (-3.4A)
None
None
None
 1.07A 4odrA-4a20A:
undetectable
4odrB-4a20A:
undetectable		 4odrA-4a20A:
17.76
4odrB-4a20A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 4a20 UBIQUITIN-LIKE
PROTEIN MDY2
(Saccharomyces
cerevisiae) 		5 / 12 THR A  97
HIS A 127
ASP A 128
SER A  93
ASN A 129
 None
SO4  A1152 (-3.8A)
SO4  A1152 (-3.4A)
None
None
 1.36A 4pooA-4a20A:
undetectable		 4pooA-4a20A:
20.11