SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 4a24 DEFORMED EPIDERMAL
AUTOREGULATORY
FACTOR 1 HOMOLOG
(Homo
sapiens) 		4 / 8 CYH A 515
HIS A 536
CYH A 540
GLY A 541
 ZN  A 602 (-2.3A)
ZN  A 602 (-3.1A)
ZN  A 602 (-2.3A)
None
 0.94A 1ekjA-4a24A:
undetectable
1ekjB-4a24A:
undetectable		 1ekjA-4a24A:
11.63
1ekjB-4a24A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4a24 DEFORMED EPIDERMAL
AUTOREGULATORY
FACTOR 1 HOMOLOG
(Homo
sapiens) 		3 / 3 CYH A 515
CYH A 540
HIS A 536
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.1A)
 0.84A 3dtuB-4a24A:
undetectable		 3dtuB-4a24A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4a24 DEFORMED EPIDERMAL
AUTOREGULATORY
FACTOR 1 HOMOLOG
(Homo
sapiens) 		3 / 3 CYH A 515
CYH A 540
HIS A 536
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.1A)
 0.81A 3dtuD-4a24A:
undetectable		 3dtuD-4a24A:
10.36