SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Z_B_ROCB505_1 (PROTEIN (PROTEASE))	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.97A	1c6zA-4a2lA: undetectable	1c6zA-4a2lA: 9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_I_BEZI518_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	ILE A 652 GLY A 651 PHE A 631 ASN A 632	None	0.81A	1oniG-4a2lA: undetectable 1oniI-4a2lA: undetectable	1oniG-4a2lA: 10.50 1oniI-4a2lA: 10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_B_ADNB1502_1 (ADENOSYLHOMOCYSTEINA SE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	LEU A 332 ASP A 318 GLY A 69 MET A 56 PHE A 58	None	1.49A	1v8bB-4a2lA: undetectable	1v8bB-4a2lA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_A_SAMA302_0 (HYPOTHETICAL PROTEIN PH0226)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	TYR A 250 ALA A 231 GLY A 236 ILE A 217 ALA A 219	None	1.14A	1ve3A-4a2lA: undetectable	1ve3A-4a2lA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VID_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 5	SER A 47 GLU A 137 TYR A 180 ASP A 49	None	1.17A	1vidA-4a2lA: undetectable	1vidA-4a2lA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	SER A 552 ASP A 594 CYH A 609	None None PGE A1785 ( 4.2A)	1.09A	2br4E-4a2lA: undetectable	2br4E-4a2lA: 13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_A_NCAA1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	ARG A 313 ARG A 91 GLN A 216 GLU A 233	None	1.00A	2c8aA-4a2lA: undetectable	2c8aA-4a2lA: 16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_2 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 9	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	1.02A	2o4pB-4a2lA: undetectable	2o4pB-4a2lA: 8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PK4_A_ACAA100_1 (HUMAN PLASMINOGEN KRINGLE 4)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	ASP A 594 TRP A 600 PHE A 620 ARG A 618	None	0.71A	2pk4A-4a2lA: undetectable	2pk4A-4a2lA: 7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PLW_A_SAMA203_1 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	SER A 84 ASP A 107 ASP A 88	None	0.74A	2plwA-4a2lA: undetectable	2plwA-4a2lA: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	PHE A 58 TYR A 718 SER A 716 VAL A 714 VAL A 670	None	1.20A	3bjmB-4a2lA: 3.1	3bjmB-4a2lA: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCJ_B_THHB401_0 (PROBABLE 5'-PHOSPHORIBOSYLGLY CINAMIDE FORMYLTRANSFERASE PURN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	LEU A 429 LEU A 449 VAL A 454 GLY A 427	None	0.73A	3dcjB-4a2lA: undetectable	3dcjB-4a2lA: 12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKQ_A_ROCA100_2 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 9	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.95A	3ekqB-4a2lA: undetectable	3ekqB-4a2lA: 8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA200_0 (ILEAL BILE ACID-BINDING PROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 5	PRO A 478 THR A 424 VAL A 454 GLY A 423	None	1.07A	3elzA-4a2lA: undetectable	3elzA-4a2lA: 11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA200_0 (ILEAL BILE ACID-BINDING PROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 5	PRO A 612 THR A 560 VAL A 588 GLY A 559	None	1.02A	3elzA-4a2lA: undetectable	3elzA-4a2lA: 11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_A_MTXA164_2 (DIHYDROFOLATE REDUCTASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 4	ILE A 700 PHE A 709 ILE A 778 THR A 687	None	1.16A	3ia4A-4a2lA: undetectable	3ia4A-4a2lA: 12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_B_LYAB514_1 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ALA A 410 LEU A 458 ILE A 513 LEU A 511 ARG A 505	None	1.16A	3k2hB-4a2lA: undetectable	3k2hB-4a2lA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_1 (HIV-1 PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	1.03A	3k4vC-4a2lA: undetectable	3k4vC-4a2lA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KIV_A_ACAA100_1 (APOLIPOPROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	ASP A 594 TRP A 600 PHE A 620 ARG A 618	None	0.83A	3kivA-4a2lA: undetectable	3kivA-4a2lA: 6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N62_A_MTLA870_0 (NITRIC OXIDE SYNTHASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	SER A 749 GLN A 706 PHE A 709 ASN A 750	None	1.26A	3n62A-4a2lA: undetectable	3n62A-4a2lA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_D_ROCD100_1 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.98A	3nduC-4a2lA: undetectable	3nduC-4a2lA: 8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PP7_B_SVRB499_1 (PYRUVATE KINASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 10	THR A 501 ASN A 546 GLY A 590 TYR A 636 GLY A 514	None	0.89A	3pp7B-4a2lA: undetectable	3pp7B-4a2lA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_C_ACHC323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	PHE A 31 TYR A 335 TYR A 297 LEU A 284	None	0.95A	3rqwC-4a2lA: undetectable 3rqwD-4a2lA: undetectable	3rqwC-4a2lA: 18.23 3rqwD-4a2lA: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_I_ACHI323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	PHE A 31 TYR A 335 TYR A 297 LEU A 284	None	0.95A	3rqwI-4a2lA: undetectable 3rqwJ-4a2lA: undetectable	3rqwI-4a2lA: 18.23 3rqwJ-4a2lA: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_J_ACHJ323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	TYR A 297 LEU A 284 PHE A 31 TYR A 335	None	0.97A	3rqwF-4a2lA: undetectable 3rqwJ-4a2lA: undetectable	3rqwF-4a2lA: 18.23 3rqwJ-4a2lA: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3M_A_DLUA398_1 (PFV INTEGRASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	ASP A 96 GLY A 99 PRO A 141 GLU A 142	None	0.96A	3s3mA-4a2lA: undetectable	3s3mA-4a2lA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3N_A_DLUA398_1 (PFV INTEGRASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	ASP A 96 GLY A 99 PRO A 141 GLU A 142	None	1.00A	3s3nA-4a2lA: undetectable	3s3nA-4a2lA: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ6_A_SAMA300_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	LEU A 179 ILE A 217 ILE A 186 ILE A 220 ASP A 193	None	1.02A	3uj6A-4a2lA: undetectable	3uj6A-4a2lA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_A_VIVA301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 11	SER A 355 LEU A 354 ILE A 422 ILE A 408 VAL A 359	None	1.13A	3w67A-4a2lA: undetectable	3w67A-4a2lA: 17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 6	GLY A 563 ASN A 586 LEU A 583 ASN A 581	None	0.92A	3zqtA-4a2lA: undetectable	3zqtA-4a2lA: 14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AFG_C_QMRC1214_1 (CAPITELLA TELETA ACHBP)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 8	TRP A 557 TYR A 565 ILE A 548 ILE A 591	None	1.05A	4afgD-4a2lA: undetectable 4afgE-4a2lA: undetectable	4afgD-4a2lA: 15.08 4afgE-4a2lA: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K0B_B_SAMB504_0 (S-ADENOSYLMETHIONINE SYNTHASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 8	ASN A 383 ARG A 388 LEU A 381 ASN A 369 ASP A 367	None	1.32A	4k0bA-4a2lA: undetectable	4k0bA-4a2lA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA505_0 (RNA POLYMERASE 3D-POL)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	CYH A 361 ASN A 632 LYS A 409	None	1.38A	4k50A-4a2lA: undetectable	4k50A-4a2lA: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOE_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA4)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	SER A 360 GLY A 404 GLY A 428 GLU A 452	None	0.85A	4koeA-4a2lA: undetectable 4koeB-4a2lA: undetectable 4koeD-4a2lA: undetectable	4koeA-4a2lA: 21.81 4koeB-4a2lA: 21.81 4koeD-4a2lA: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L7I_B_SAMB501_0 (S-ADENOSYLMETHIONINE SYNTHASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 8	ASN A 383 ARG A 388 LEU A 381 ASN A 369 ASP A 367	None	1.33A	4l7iA-4a2lA: undetectable	4l7iA-4a2lA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_A_TMQA202_2 (DIHYDROFOLATE REDUCTASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	TRP A 705 GLN A 675 THR A 687	None	0.88A	4m2xA-4a2lA: undetectable	4m2xA-4a2lA: 12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJV_A_RITA500_1 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	1.05A	4njvA-4a2lA: undetectable	4njvA-4a2lA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJV_A_RITA500_2 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 11	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.95A	4njvB-4a2lA: undetectable	4njvB-4a2lA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJV_D_RITD500_2 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.95A	4njvD-4a2lA: undetectable	4njvD-4a2lA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QGI_A_ROCA101_2 (PROTEASE)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 11	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	0.96A	4qgiB-4a2lA: undetectable	4qgiB-4a2lA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 7	GLY A 404 GLY A 428 GLU A 452 SER A 360	None	0.92A	4z53A-4a2lA: undetectable 4z53B-4a2lA: undetectable	4z53A-4a2lA: 23.32 4z53B-4a2lA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_0 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	GLN A 627 GLY A 606 TYR A 589 ASN A 632 VAL A 359	None	1.21A	5d0yA-4a2lA: undetectable	5d0yA-4a2lA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQX_A_ROCA101_2 (PROTEASE E35D-SQV)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 9	ARG A 505 VAL A 558 GLY A 515 ILE A 500 ILE A 548	None	1.02A	5kqxB-4a2lA: undetectable	5kqxB-4a2lA: 8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	TYR A 250 SER A 293 TRP A 229	None	0.85A	5n8jB-4a2lA: undetectable	5n8jB-4a2lA: 12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	TYR A 250 SER A 293 TRP A 229	None	0.90A	5n8jA-4a2lA: undetectable	5n8jA-4a2lA: 12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	TYR A 250 SER A 293 TRP A 229	None	0.93A	5n8jD-4a2lA: undetectable	5n8jD-4a2lA: 12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	TYR A 577 PRO A 612 LEU A 599	None	0.91A	6beoA-4a2lA: undetectable	6beoA-4a2lA: 2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DEB_B_MTXB303_1 (BIFUNCTIONAL PROTEIN FOLD)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	4 / 5	TYR A 718 GLN A 320 GLY A 326 ILE A 34	None	1.20A	6debB-4a2lA: undetectable	6debB-4a2lA: 8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_C_DAHC123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 11	THR A 666 SER A 765 GLY A 767 ILE A 338 ILE A 719	None	0.98A	6ebzC-4a2lA: undetectable	6ebzC-4a2lA: 7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_A_QPSA602_1 (-)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	VAL A 587 ASP A 376 ASN A 585 GLN A 627 GLY A 606	None	1.44A	6gnfA-4a2lA: undetectable	6gnfA-4a2lA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_2 (-)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	5 / 12	VAL A 587 ASP A 376 ASN A 585 GLN A 627 GLY A 606	None	1.40A	6gnfC-4a2lA: undetectable	6gnfC-4a2lA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4a2l	TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE (Bacteroides thetaiotaomicron)	3 / 3	ARG A 576 LEU A 543 PHE A 544	None	0.66A	6nknP-4a2lA: undetectable	6nknP-4a2lA: 15.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C6Z_B_ROCB505_1","PROTEIN (PROTEASE);PROTEIN (PROTEASE)","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.97A","1c6zA-4a2lA:undetectable","1c6zA-4a2lA:9.75"],["1ONI_I_BEZI518_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ILE A 652;GLY A 651;PHE A 631;ASN A 632","None","0.81A","1oniG-4a2lA:undetectable;1oniI-4a2lA:undetectable","1oniG-4a2lA:10.50;1oniI-4a2lA:10.50"],["1V8B_B_ADNB1502_1","ADENOSYLHOMOCYSTEINASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"LEU A 332;ASP A 318;GLY A  69;MET A  56;PHE A  58","None","1.49A","1v8bB-4a2lA:undetectable","1v8bB-4a2lA:21.25"],["1VE3_A_SAMA302_0","HYPOTHETICAL PROTEIN PH0226","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"TYR A 250;ALA A 231;GLY A 236;ILE A 217;ALA A 219","None","1.14A","1ve3A-4a2lA:undetectable","1ve3A-4a2lA:14.52"],["1VID_A_SAMA301_1","CATECHOL O-METHYLTRANSFERASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"SER A  47;GLU A 137;TYR A 180;ASP A  49","None","1.17A","1vidA-4a2lA:undetectable","1vidA-4a2lA:15.48"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"SER A 552;ASP A 594;CYH A 609","None;None;PGE A1785 ( 4.2A)","1.09A","2br4E-4a2lA:undetectable","2br4E-4a2lA:13.71"],["2C8A_A_NCAA1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ARG A 313;ARG A  91;GLN A 216;GLU A 233","None","1.00A","2c8aA-4a2lA:undetectable","2c8aA-4a2lA:16.19"],["2O4P_A_TPVA300_2","PROTEASE;PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","1.02A","2o4pB-4a2lA:undetectable","2o4pB-4a2lA:8.46"],["2PK4_A_ACAA100_1","HUMAN PLASMINOGEN KRINGLE 4","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ASP A 594;TRP A 600;PHE A 620;ARG A 618","None","0.71A","2pk4A-4a2lA:undetectable","2pk4A-4a2lA:7.71"],["2PLW_A_SAMA203_1","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"SER A  84;ASP A 107;ASP A  88","None","0.74A","2plwA-4a2lA:undetectable","2plwA-4a2lA:13.61"],["3BJM_B_BJMB2_1","DIPEPTIDYL PEPTIDASE 4","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"PHE A  58;TYR A 718;SER A 716;VAL A 714;VAL A 670","None","1.20A","3bjmB-4a2lA:3.1","3bjmB-4a2lA:22.80"],["3DCJ_B_THHB401_0","PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"LEU A 429;LEU A 449;VAL A 454;GLY A 427","None","0.73A","3dcjB-4a2lA:undetectable","3dcjB-4a2lA:12.31"],["3EKQ_A_ROCA100_2","PROTEASE;PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.95A","3ekqB-4a2lA:undetectable","3ekqB-4a2lA:8.85"],["3ELZ_A_CHDA200_0","ILEAL BILE ACID-BINDING PROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"PRO A 478;THR A 424;VAL A 454;GLY A 423","None","1.07A","3elzA-4a2lA:undetectable","3elzA-4a2lA:11.10"],["3ELZ_A_CHDA200_0","ILEAL BILE ACID-BINDING PROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"PRO A 612;THR A 560;VAL A 588;GLY A 559","None","1.02A","3elzA-4a2lA:undetectable","3elzA-4a2lA:11.10"],["3IA4_A_MTXA164_2","DIHYDROFOLATE REDUCTASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ILE A 700;PHE A 709;ILE A 778;THR A 687","None","1.16A","3ia4A-4a2lA:undetectable","3ia4A-4a2lA:12.45"],["3K2H_B_LYAB514_1","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ALA A 410;LEU A 458;ILE A 513;LEU A 511;ARG A 505","None","1.16A","3k2hB-4a2lA:undetectable","3k2hB-4a2lA:20.20"],["3K4V_D_ROCD201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","1.03A","3k4vC-4a2lA:undetectable","3k4vC-4a2lA:8.70"],["3KIV_A_ACAA100_1","APOLIPOPROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ASP A 594;TRP A 600;PHE A 620;ARG A 618","None","0.83A","3kivA-4a2lA:undetectable","3kivA-4a2lA:6.88"],["3N62_A_MTLA870_0","NITRIC OXIDE SYNTHASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"SER A 749;GLN A 706;PHE A 709;ASN A 750","None","1.26A","3n62A-4a2lA:undetectable","3n62A-4a2lA:19.21"],["3NDU_D_ROCD100_1","PROTEASE;PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.98A","3nduC-4a2lA:undetectable","3nduC-4a2lA:8.40"],["3PP7_B_SVRB499_1","PYRUVATE KINASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"THR A 501;ASN A 546;GLY A 590;TYR A 636;GLY A 514","None","0.89A","3pp7B-4a2lA:undetectable","3pp7B-4a2lA:19.88"],["3RQW_C_ACHC323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"PHE A  31;TYR A 335;TYR A 297;LEU A 284","None","0.95A","3rqwC-4a2lA:undetectable;3rqwD-4a2lA:undetectable","3rqwC-4a2lA:18.23;3rqwD-4a2lA:18.23"],["3RQW_I_ACHI323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"PHE A  31;TYR A 335;TYR A 297;LEU A 284","None","0.95A","3rqwI-4a2lA:undetectable;3rqwJ-4a2lA:undetectable","3rqwI-4a2lA:18.23;3rqwJ-4a2lA:18.23"],["3RQW_J_ACHJ323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"TYR A 297;LEU A 284;PHE A  31;TYR A 335","None","0.97A","3rqwF-4a2lA:undetectable;3rqwJ-4a2lA:undetectable","3rqwF-4a2lA:18.23;3rqwJ-4a2lA:18.23"],["3S3M_A_DLUA398_1","PFV INTEGRASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ASP A  96;GLY A  99;PRO A 141;GLU A 142","None","0.96A","3s3mA-4a2lA:undetectable","3s3mA-4a2lA:19.92"],["3S3N_A_DLUA398_1","PFV INTEGRASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"ASP A  96;GLY A  99;PRO A 141;GLU A 142","None","1.00A","3s3nA-4a2lA:undetectable","3s3nA-4a2lA:19.77"],["3UJ6_A_SAMA300_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"LEU A 179;ILE A 217;ILE A 186;ILE A 220;ASP A 193","None","1.02A","3uj6A-4a2lA:undetectable","3uj6A-4a2lA:16.43"],["3W67_A_VIVA301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"SER A 355;LEU A 354;ILE A 422;ILE A 408;VAL A 359","None","1.13A","3w67A-4a2lA:undetectable","3w67A-4a2lA:17.52"],["3ZQT_A_30ZA1920_1","ANDROGEN RECEPTOR","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"GLY A 563;ASN A 586;LEU A 583;ASN A 581","None","0.92A","3zqtA-4a2lA:undetectable","3zqtA-4a2lA:14.32"],["4AFG_C_QMRC1214_1","CAPITELLA TELETA ACHBP;CAPITELLA TELETA ACHBP;CAPITELLA TELETA ACHBP","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"TRP A 557;TYR A 565;ILE A 548;ILE A 591","None","1.05A","4afgD-4a2lA:undetectable;4afgE-4a2lA:undetectable","4afgD-4a2lA:15.08;4afgE-4a2lA:15.08"],["4K0B_B_SAMB504_0","S-ADENOSYLMETHIONINE SYNTHASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ASN A 383;ARG A 388;LEU A 381;ASN A 369;ASP A 367","None","1.32A","4k0bA-4a2lA:undetectable","4k0bA-4a2lA:20.60"],["4K50_A_ACTA505_0","RNA POLYMERASE 3D-POL","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"CYH A 361;ASN A 632;LYS A 409","None","1.38A","4k50A-4a2lA:undetectable","4k50A-4a2lA:21.24"],["4KOE_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B;E-SITE DNA4","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"SER A 360;GLY A 404;GLY A 428;GLU A 452","None","0.85A","4koeA-4a2lA:undetectable;4koeB-4a2lA:undetectable;4koeD-4a2lA:undetectable","4koeA-4a2lA:21.81;4koeB-4a2lA:21.81;4koeD-4a2lA:16.86"],["4L7I_B_SAMB501_0","S-ADENOSYLMETHIONINE SYNTHASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ASN A 383;ARG A 388;LEU A 381;ASN A 369;ASP A 367","None","1.33A","4l7iA-4a2lA:undetectable","4l7iA-4a2lA:20.60"],["4M2X_A_TMQA202_2","DIHYDROFOLATE REDUCTASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"TRP A 705;GLN A 675;THR A 687","None","0.88A","4m2xA-4a2lA:undetectable","4m2xA-4a2lA:12.83"],["4NJV_A_RITA500_1","PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","1.05A","4njvA-4a2lA:undetectable","4njvA-4a2lA:8.70"],["4NJV_A_RITA500_2","PROTEASE;PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.95A","4njvB-4a2lA:undetectable","4njvB-4a2lA:8.70"],["4NJV_D_RITD500_2","PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.95A","4njvD-4a2lA:undetectable","4njvD-4a2lA:8.70"],["4QGI_A_ROCA101_2","PROTEASE;PROTEASE","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","0.96A","4qgiB-4a2lA:undetectable","4qgiB-4a2lA:8.33"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"GLY A 404;GLY A 428;GLU A 452;SER A 360","None","0.92A","4z53A-4a2lA:undetectable;4z53B-4a2lA:undetectable","4z53A-4a2lA:23.32;4z53B-4a2lA:23.32"],["5D0Y_A_FOLA201_0","CONSERVED HYPOTHETICAL MEMBRANE PROTEIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"GLN A 627;GLY A 606;TYR A 589;ASN A 632;VAL A 359","None","1.21A","5d0yA-4a2lA:undetectable","5d0yA-4a2lA:12.69"],["5KQX_A_ROCA101_2","PROTEASE E35D-SQV;PROTEASE E35D-SQV","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"ARG A 505;VAL A 558;GLY A 515;ILE A 500;ILE A 548","None","1.02A","5kqxB-4a2lA:undetectable","5kqxB-4a2lA:8.84"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"TYR A 250;SER A 293;TRP A 229","None","0.85A","5n8jB-4a2lA:undetectable","5n8jB-4a2lA:12.58"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"TYR A 250;SER A 293;TRP A 229","None","0.90A","5n8jA-4a2lA:undetectable","5n8jA-4a2lA:12.58"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"TYR A 250;SER A 293;TRP A 229","None","0.93A","5n8jD-4a2lA:undetectable","5n8jD-4a2lA:12.58"],["6BEO_A_DHIA4_0","(DPR)PY(DHI)PKDL(DGN)","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"TYR A 577;PRO A 612;LEU A 599","None","0.91A","6beoA-4a2lA:undetectable","6beoA-4a2lA:2.43"],["6DEB_B_MTXB303_1","BIFUNCTIONAL PROTEIN FOLD","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",4,"TYR A 718;GLN A 320;GLY A 326;ILE A  34","None","1.20A","6debB-4a2lA:undetectable","6debB-4a2lA:8.63"],["6EBZ_C_DAHC123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"THR A 666;SER A 765;GLY A 767;ILE A 338;ILE A 719","None","0.98A","6ebzC-4a2lA:undetectable","6ebzC-4a2lA:7.31"],["6GNF_A_QPSA602_1","-","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"VAL A 587;ASP A 376;ASN A 585;GLN A 627;GLY A 606","None","1.44A","6gnfA-4a2lA:undetectable","6gnfA-4a2lA:20.90"],["6GNF_C_QPSC602_2","-","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",5,"VAL A 587;ASP A 376;ASN A 585;GLN A 627;GLY A 606","None","1.40A","6gnfC-4a2lA:undetectable","6gnfC-4a2lA:20.90"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4a2l","TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE\/RESPONSE","Bacteroides thetaiotaomicron",3,"ARG A 576;LEU A 543;PHE A 544","None","0.66A","6nknP-4a2lA:undetectable","6nknP-4a2lA:15.67"]]