SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 4 THR A 176
LEU A 173
LEU A 184
GLN A 518
None
1.21A 1fbmA-4a2qA:
undetectable
1fbmA-4a2qA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 9 PHE A 369
LEU A 389
ILE A 353
VAL A 337
ILE A 341
None
1.22A 1gebA-4a2qA:
undetectable
1gebA-4a2qA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 11 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.47A 1jb0B-4a2qA:
undetectable
1jb0B-4a2qA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 ILE A 477
ILE A 476
GLU A 557
ALA A 559
ASN A 609
None
1.25A 1jtxA-4a2qA:
undetectable
1jtxA-4a2qA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
None
1.04A 1qhsA-4a2qA:
2.6
1qhsA-4a2qA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
None
1.00A 1qhyA-4a2qA:
2.5
1qhyA-4a2qA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 PRO A 579
LEU A 153
ILE A 150
SER A 141
None
1.11A 1sbrA-4a2qA:
undetectable
1sbrB-4a2qA:
undetectable
1sbrA-4a2qA:
14.38
1sbrB-4a2qA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.91A 1v55A-4a2qA:
1.1
1v55J-4a2qA:
undetectable
1v55A-4a2qA:
18.94
1v55J-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
3 / 3 SER A 642
GLU A 570
ASP A 117
None
0.88A 2avdB-4a2qA:
undetectable
2avdB-4a2qA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 LEU A  57
LEU A  20
LEU A  84
ALA A  85
ILE A  88
None
0.95A 2bxpA-4a2qA:
3.5
2bxpA-4a2qA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.88A 2einN-4a2qA:
undetectable
2einW-4a2qA:
undetectable
2einN-4a2qA:
18.94
2einW-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
3 / 3 SER A 413
THR A 443
PHE A 777
None
0.77A 2x91A-4a2qA:
3.2
2x91A-4a2qA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 ILE A 137
GLU A 133
LEU A 173
ILE A 125
MET A 113
None
1.05A 2xkwB-4a2qA:
undetectable
2xkwB-4a2qA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.84A 3ag1N-4a2qA:
4.4
3ag1W-4a2qA:
undetectable
3ag1N-4a2qA:
18.94
3ag1W-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 LEU A 173
GLY A 177
LEU A 169
SER A 168
None
0.96A 3aiaA-4a2qA:
undetectable
3aiaA-4a2qA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 THR A 112
LEU A 169
LEU A 121
THR A 176
LEU A 106
None
1.43A 3fsuA-4a2qA:
undetectable
3fsuA-4a2qA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
3 / 3 ARG A 522
GLU A 544
ASP A 551
None
0.77A 3g2oA-4a2qA:
2.8
3g2oA-4a2qA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 10 ILE A 137
PRO A 118
LYS A 152
GLY A 149
LEU A 129
None
1.41A 3ik6B-4a2qA:
undetectable
3ik6E-4a2qA:
undetectable
3ik6B-4a2qA:
15.65
3ik6E-4a2qA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 10 LEU A 129
ILE A 137
PRO A 118
LYS A 152
GLY A 149
None
1.40A 3ik6B-4a2qA:
undetectable
3ik6E-4a2qA:
undetectable
3ik6B-4a2qA:
15.65
3ik6E-4a2qA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 8 ILE A 150
PRO A 118
SER A 141
GLY A 149
ASN A 574
None
1.31A 3lslA-4a2qA:
undetectable
3lslD-4a2qA:
undetectable
3lslA-4a2qA:
15.22
3lslD-4a2qA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ALA A 111
ILE A 541
HIS A 545
VAL A 575
None
0.95A 3nneG-4a2qA:
undetectable
3nneG-4a2qA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 11 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.47A 3pcqB-4a2qA:
undetectable
3pcqB-4a2qA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 PRO A 118
MET A 113
GLY A 578
PRO A 579
None
1.23A 3ucbB-4a2qA:
undetectable
3ucbB-4a2qA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.98A 3wg7N-4a2qA:
2.4
3wg7W-4a2qA:
undetectable
3wg7N-4a2qA:
18.94
3wg7W-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 5 LEU A 371
ILE A 346
ALA A 294
PHE A 285
None
1.07A 4dc3B-4a2qA:
undetectable
4dc3B-4a2qA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 LEU A 157
LEU A 106
ILE A 109
MET A 113
None
1.00A 4do3B-4a2qA:
undetectable
4do3B-4a2qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 8 GLU A 511
GLN A 518
PHE A 540
ILE A 541
None
0.96A 4dx7B-4a2qA:
2.2
4dx7B-4a2qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 9 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.47A 4fe1B-4a2qA:
undetectable
4fe1B-4a2qA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 MET A  76
LEU A  77
ILE A  88
LEU A  73
LEU A  96
None
1.18A 4j24D-4a2qA:
undetectable
4j24D-4a2qA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 8 PHE A 369
LEU A 299
VAL A 337
ILE A 341
None
0.87A 4l4cB-4a2qA:
undetectable
4l4cB-4a2qA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 11 GLU A   5
LYS A   6
LEU A   9
LEU A  61
LEU A  57
None
0.96A 4wg0C-4a2qA:
undetectable
4wg0D-4a2qA:
undetectable
4wg0E-4a2qA:
undetectable
4wg0C-4a2qA:
1.63
4wg0D-4a2qA:
1.63
4wg0E-4a2qA:
1.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 11 GLU A   5
LYS A   6
LEU A   9
LEU A  61
LEU A  57
None
0.97A 4wg0E-4a2qA:
undetectable
4wg0F-4a2qA:
undetectable
4wg0G-4a2qA:
undetectable
4wg0E-4a2qA:
1.63
4wg0F-4a2qA:
1.63
4wg0G-4a2qA:
1.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LEU A  61
GLU A   5
LYS A   6
LEU A   9
None
0.78A 4wg0L-4a2qA:
undetectable
4wg0M-4a2qA:
undetectable
4wg0L-4a2qA:
1.63
4wg0M-4a2qA:
1.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 11 LEU A 612
LEU A 619
LEU A 644
THR A 698
VAL A 742
None
1.13A 4x20D-4a2qA:
undetectable
4x20D-4a2qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 10 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.47A 4xk8B-4a2qA:
2.3
4xk8B-4a2qA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LYS A 738
ARG A 463
ASP A 461
TYR A 625
None
1.36A 5a06A-4a2qA:
undetectable
5a06A-4a2qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LYS A 738
ARG A 463
ASP A 461
TYR A 625
None
1.39A 5a06C-4a2qA:
2.2
5a06C-4a2qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LYS A 738
ARG A 463
ASP A 461
TYR A 625
None
1.35A 5a06D-4a2qA:
undetectable
5a06D-4a2qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LYS A 738
ARG A 463
ASP A 461
TYR A 625
None
1.36A 5a06E-4a2qA:
undetectable
5a06E-4a2qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 LYS A 738
ARG A 463
ASP A 461
TYR A 625
None
1.34A 5a06F-4a2qA:
2.2
5a06F-4a2qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 GLY A 417
MET A 762
CYH A 266
THR A 411
LEU A 432
None
1.47A 5fhzD-4a2qA:
undetectable
5fhzD-4a2qA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 4 GLU A 597
PRO A 596
ILE A 599
LEU A 598
None
1.24A 5m45A-4a2qA:
undetectable
5m45A-4a2qA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 4 GLU A 597
PRO A 596
ILE A 599
LEU A 598
None
1.23A 5m45G-4a2qA:
undetectable
5m45G-4a2qA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 4 GLU A 597
PRO A 596
ILE A 599
LEU A 598
None
1.28A 5m45J-4a2qA:
undetectable
5m45J-4a2qA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 10 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.45A 5oy0b-4a2qA:
1.9
5oy0b-4a2qA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 MET A  76
LEU A  77
ILE A  88
LEU A  73
LEU A  96
None
1.11A 5toaB-4a2qA:
undetectable
5toaB-4a2qA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 12 ALA A  53
LEU A  84
ILE A  88
VAL A  60
ASP A  74
None
1.30A 5vlmG-4a2qA:
2.3
5vlmG-4a2qA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.92A 5xdqN-4a2qA:
2.1
5xdqW-4a2qA:
undetectable
5xdqN-4a2qA:
18.94
5xdqW-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.98A 5z86N-4a2qA:
undetectable
5z86W-4a2qA:
undetectable
5z86N-4a2qA:
18.94
5z86W-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 6 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.99A 5zcoN-4a2qA:
2.1
5zcoW-4a2qA:
undetectable
5zcoN-4a2qA:
18.94
5zcoW-4a2qA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 5 PRO A 268
THR A 269
GLN A 727
MET A 455
None
1.33A 6fgdA-4a2qA:
2.0
6fgdA-4a2qA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
6 / 11 PHE A 358
LEU A 354
GLY A 361
PHE A 369
ILE A 368
ILE A 341
None
1.33A 6gp2A-4a2qA:
undetectable
6gp2A-4a2qA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
6 / 11 PHE A 358
LEU A 354
GLY A 361
PHE A 369
ILE A 368
ILE A 341
None
1.30A 6gp2B-4a2qA:
undetectable
6gp2B-4a2qA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
5 / 9 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
None
1.46A 6hqbB-4a2qA:
0.4
6hqbB-4a2qA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos)
4 / 7 ILE A 438
MET A 390
THR A 391
LEU A 394
None
0.75A 6nmpA-4a2qA:
0.9
6nmpJ-4a2qA:
undetectable
6nmpA-4a2qA:
18.94
6nmpJ-4a2qA:
5.46