SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 4a2v RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 LEU A 810
PHE A 895
ARG A 867
 None
 0.59A 1xdkF-4a2vA:
undetectable		 1xdkF-4a2vA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4a2v RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 7 LEU A 836
ILE A 828
MET A 926
GLU A 925
 None
 0.99A 2qqdA-4a2vA:
undetectable
2qqdE-4a2vA:
undetectable		 2qqdA-4a2vA:
20.65
2qqdE-4a2vA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 4a2v RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 VAL A 889
GLY A 876
LYS A 891
 None
 0.78A 4k50A-4a2vA:
undetectable		 4k50A-4a2vA:
15.65