SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 9 PHE A 369
LEU A 389
ILE A 353
VAL A 337
ILE A 341
 None
 1.28A 1gebA-4a2wA:
undetectable		 1gebA-4a2wA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 5 TYR A 393
LEU A 363
THR A 370
ARG A 292
 None
 1.27A 1i2wA-4a2wA:
undetectable		 1i2wA-4a2wA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 11 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
 None
 1.48A 1jb0B-4a2wA:
undetectable		 1jb0B-4a2wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 ILE A 477
ILE A 476
GLU A 557
ALA A 559
ASN A 609
 None
 1.20A 1jtxA-4a2wA:
undetectable		 1jtxA-4a2wA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 ALA A 147
LEU A 487
GLY A 578
TYR A 580
LEU A 583
 None
 1.14A 1qabF-4a2wA:
undetectable		 1qabF-4a2wA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
 None
 0.99A 1qhsA-4a2wA:
undetectable		 1qhsA-4a2wA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
 None
 0.96A 1qhyA-4a2wA:
2.6		 1qhyA-4a2wA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 LEU A 114
HIS A 545
ILE A 541
 None
 0.63A 1s9pB-4a2wA:
undetectable		 1s9pB-4a2wA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 PRO A 579
LEU A 153
ILE A 150
SER A 141
 None
 1.10A 1sbrA-4a2wA:
undetectable
1sbrB-4a2wA:
undetectable		 1sbrA-4a2wA:
11.83
1sbrB-4a2wA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 4 LEU A 546
LEU A 480
SER A 478
LEU A 553
 None
 1.15A 1ya3A-4a2wA:
undetectable		 1ya3A-4a2wA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 ILE A 122
ALA A 120
ILE A 150
LEU A 157
ILE A 125
 None
 1.03A 2cd2A-4a2wA:
undetectable		 2cd2A-4a2wA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 10 ALA A  52
ALA A  54
GLU A  17
ALA A  53
SER A  50
 None
 1.12A 2r2vC-4a2wA:
undetectable
2r2vF-4a2wA:
undetectable
2r2vG-4a2wA:
undetectable		 2r2vC-4a2wA:
3.32
2r2vF-4a2wA:
3.32
2r2vG-4a2wA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 SER A 413
THR A 443
PHE A 777
 None
 0.76A 2x91A-4a2wA:
3.0		 2x91A-4a2wA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 ILE A 137
GLU A 133
LEU A 173
ILE A 125
MET A 113
 None
 1.25A 2xkwB-4a2wA:
undetectable		 2xkwB-4a2wA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 5 ARG A 560
ASP A 563
GLU A 650
LYS A 646
 None
 1.44A 2xrzA-4a2wA:
undetectable
2xrzB-4a2wA:
undetectable		 2xrzA-4a2wA:
20.09
2xrzB-4a2wA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 LEU A 173
GLY A 177
LEU A 169
SER A 168
 None
 0.94A 3aiaA-4a2wA:
undetectable		 3aiaA-4a2wA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 PRO A 579
PHE A 572
LYS A 576
 None
 1.12A 3bjwG-4a2wA:
1.9		 3bjwG-4a2wA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 LEU A 129
GLU A 155
ILE A 154
 None
 0.60A 3czhA-4a2wA:
undetectable		 3czhA-4a2wA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 ILE A 407
TYR A 386
ILE A 373
HIS A 284
 None
 1.13A 3eteA-4a2wA:
undetectable
3eteE-4a2wA:
undetectable		 3eteA-4a2wA:
19.67
3eteE-4a2wA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 5 ILE A 407
TYR A 386
ILE A 373
HIS A 284
 None
 1.11A 3eteB-4a2wA:
undetectable
3eteC-4a2wA:
undetectable		 3eteB-4a2wA:
19.67
3eteC-4a2wA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 7 ILE A 373
HIS A 284
ILE A 407
TYR A 386
 None
 1.12A 3eteD-4a2wA:
undetectable
3eteF-4a2wA:
undetectable		 3eteD-4a2wA:
19.67
3eteF-4a2wA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 ARG A 522
GLU A 544
ASP A 551
 None
 0.84A 3g2oA-4a2wA:
undetectable		 3g2oA-4a2wA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 ARG A 756
ILE A 726
THR A 631
 None
 0.72A 3ia4D-4a2wA:
undetectable		 3ia4D-4a2wA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 10 LEU A 129
ILE A 137
PRO A 118
LYS A 152
GLY A 149
 None
 1.46A 3ik6B-4a2wA:
undetectable
3ik6E-4a2wA:
undetectable		 3ik6B-4a2wA:
14.70
3ik6E-4a2wA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 ALA A 111
ILE A 541
HIS A 545
VAL A 575
 None
 0.89A 3nneG-4a2wA:
undetectable		 3nneG-4a2wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 11 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
 None
 1.48A 3pcqB-4a2wA:
undetectable		 3pcqB-4a2wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 7 PRO A 118
MET A 113
GLY A 578
PRO A 579
 None
 1.33A 3ucbB-4a2wA:
undetectable		 3ucbB-4a2wA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 LEU A 129
LEU A 121
ILE A 154
ILE A 137
TYR A 178
 None
 1.46A 4a79B-4a2wA:
undetectable		 4a79B-4a2wA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 5 ILE A 109
ALA A 181
MET A 113
ARG A 547
 None
 1.25A 4ac9B-4a2wA:
undetectable
4ac9C-4a2wA:
undetectable		 4ac9B-4a2wA:
20.56
4ac9C-4a2wA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 5 ILE A 109
ALA A 181
MET A 113
ARG A 547
 None
 1.27A 4acaB-4a2wA:
2.1
4acaC-4a2wA:
2.1		 4acaB-4a2wA:
20.56
4acaC-4a2wA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 LEU A 157
LEU A 106
ILE A 109
MET A 113
 None
 0.98A 4do3B-4a2wA:
1.4		 4do3B-4a2wA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 8 GLU A 511
GLN A 518
PHE A 540
ILE A 541
 None
 0.99A 4dx7B-4a2wA:
2.8		 4dx7B-4a2wA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 9 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
 None
 1.48A 4fe1B-4a2wA:
undetectable		 4fe1B-4a2wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 11 LEU A 612
LEU A 619
LEU A 644
THR A 698
VAL A 742
 None
 1.13A 4x20D-4a2wA:
undetectable		 4x20D-4a2wA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 4 ILE A 514
ARG A 489
TYR A 510
GLU A 485
 None
 1.46A 4zzbD-4a2wA:
2.9		 4zzbD-4a2wA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 GLY A 417
MET A 762
CYH A 266
THR A 411
LEU A 432
 None
 1.42A 5fhzD-4a2wA:
undetectable		 5fhzD-4a2wA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 4 GLU A 597
PRO A 596
ILE A 599
LEU A 598
 None
 1.31A 5m45G-4a2wA:
0.0		 5m45G-4a2wA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 6 ILE A 109
MET A 113
ALA A 181
LEU A 184
 None
 0.85A 5mvmB-4a2wA:
3.2
5mvmC-4a2wA:
3.1		 5mvmB-4a2wA:
6.43
5mvmC-4a2wA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 10 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
 None
 1.45A 5oy0b-4a2wA:
1.9		 5oy0b-4a2wA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 GLY A 361
VAL A 297
LEU A 299
SER A 336
ILE A 341
 None
 1.20A 5vooA-4a2wA:
undetectable		 5vooA-4a2wA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 GLY A 361
VAL A 297
LEU A 299
SER A 336
ILE A 341
 None
 1.16A 5vooB-4a2wA:
undetectable		 5vooB-4a2wA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 12 GLY A 361
VAL A 297
LEU A 299
SER A 336
ILE A 341
 None
 1.20A 5vooE-4a2wA:
undetectable		 5vooE-4a2wA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		3 / 3 LYS A 780
SER A 434
SER A 431
 None
 0.99A 6gbfA-4a2wA:
undetectable		 6gbfA-4a2wA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		6 / 11 PHE A 358
LEU A 354
GLY A 361
PHE A 369
ILE A 368
ILE A 341
 None
 1.26A 6gp2A-4a2wA:
undetectable		 6gp2A-4a2wA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		6 / 11 PHE A 358
LEU A 354
GLY A 361
PHE A 369
ILE A 368
ILE A 341
 None
 1.24A 6gp2B-4a2wA:
undetectable		 6gp2B-4a2wA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		5 / 9 MET A 481
SER A 478
ILE A 555
ALA A 564
LEU A 568
 None
 1.45A 6hqbB-4a2wA:
undetectable		 6hqbB-4a2wA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 7 THR A 507
ARG A 468
HIS A 470
GLU A 557
 None
 1.36A 6mn4E-4a2wA:
undetectable		 6mn4E-4a2wA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4a2w RETINOIC ACID
INDUCIBLE PROTEIN I
(Anas
platyrhynchos) 		4 / 7 ASP A 551
ARG A 547
GLU A 544
GLU A 183
 None
 1.24A 6mn5B-4a2wA:
undetectable		 6mn5B-4a2wA:
6.21