SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	4a2y	EOSINOPHIL CATIONIC PROTEIN (Homo sapiens)	5 / 12	THR A 42 ILE A 30 ASN A 31 PHE A 43 HIS A 82	None	1.47A	2vdyA-4a2yA: undetectable	2vdyA-4a2yA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	4a2y	EOSINOPHIL CATIONIC PROTEIN (Homo sapiens)	5 / 12	THR A 42 ILE A 30 ASN A 31 PHE A 43 HIS A 82	None	1.39A	2vdyB-4a2yA: undetectable	2vdyB-4a2yA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	4a2y	EOSINOPHIL CATIONIC PROTEIN (Homo sapiens)	5 / 12	THR A 42 ILE A 30 ASN A 31 PHE A 43 HIS A 82	None	1.44A	4c49B-4a2yA: undetectable	4c49B-4a2yA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_ACTA405_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	4a2y	EOSINOPHIL CATIONIC PROTEIN (Homo sapiens)	3 / 3	GLN A 9 THR A 6 ASP A 118	None	0.75A	5k9dA-4a2yA: undetectable	5k9dA-4a2yA: 17.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VDY_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","4a2y","EOSINOPHIL CATIONIC PROTEIN","Homo sapiens",5,"THR A  42;ILE A  30;ASN A  31;PHE A  43;HIS A  82","None","1.47A","2vdyA-4a2yA:undetectable","2vdyA-4a2yA:14.68"],["2VDY_B_HCYB1384_1","CORTICOSTEROID-BINDING GLOBULIN","4a2y","EOSINOPHIL CATIONIC PROTEIN","Homo sapiens",5,"THR A  42;ILE A  30;ASN A  31;PHE A  43;HIS A  82","None","1.39A","2vdyB-4a2yA:undetectable","2vdyB-4a2yA:14.68"],["4C49_B_HCYB1384_1","CORTICOSTEROID-BINDING GLOBULIN","4a2y","EOSINOPHIL CATIONIC PROTEIN","Homo sapiens",5,"THR A  42;ILE A  30;ASN A  31;PHE A  43;HIS A  82","None","1.44A","4c49B-4a2yA:undetectable","4c49B-4a2yA:15.50"],["5K9D_A_ACTA405_0","DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL","4a2y","EOSINOPHIL CATIONIC PROTEIN","Homo sapiens",3,"GLN A   9;THR A   6;ASP A 118","None","0.75A","5k9dA-4a2yA:undetectable","5k9dA-4a2yA:17.68"]]