SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4a42 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 10 ILE A1616
PHE A1604
ASN A1591
ILE A1576
ILE A1550
 None
 0.96A 1j3jA-4a42A:
undetectable		 1j3jA-4a42A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4a42 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 11 ILE A1616
PHE A1604
ASN A1591
ILE A1576
ILE A1550
 None
 0.90A 2blaA-4a42A:
undetectable		 2blaA-4a42A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4a42 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 ILE A1547
ILE A1618
PHE A1539
ASP A1551
ILE A1564
 None
 1.06A 5lg3E-4a42A:
undetectable		 5lg3E-4a42A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4a42 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 10 ILE A1547
ILE A1618
PHE A1539
ASP A1551
ILE A1564
 None
 1.10A 5lg3F-4a42A:
undetectable		 5lg3F-4a42A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4a42 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 ILE A1547
ILE A1618
PHE A1539
ASP A1551
ILE A1564
 None
 1.11A 5lg3J-4a42A:
undetectable		 5lg3J-4a42A:
21.64