SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 1.00A 1dfoA-4a5aA:
undetectable		 1dfoA-4a5aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 1.01A 1dfoB-4a5aA:
undetectable		 1dfoB-4a5aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 1.01A 1dfoC-4a5aA:
undetectable		 1dfoC-4a5aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 1.01A 1dfoD-4a5aA:
undetectable		 1dfoD-4a5aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 0.99A 1eqbA-4a5aA:
undetectable		 1eqbA-4a5aA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 0.99A 1eqbB-4a5aA:
undetectable		 1eqbB-4a5aA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 0.99A 1eqbC-4a5aA:
undetectable		 1eqbC-4a5aA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 563
LEU A 567
VAL A 474
ALA A 497
SER A 282
 None
None
None
None
ANP  A 700 (-3.6A)
 0.99A 1eqbD-4a5aA:
undetectable		 1eqbD-4a5aA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 7 SER A 282
GLU A 236
GLU A 235
GLU A 465
 ANP  A 700 (-3.6A)
ANP  A 700 ( 4.0A)
None
None
 1.12A 1knyA-4a5aA:
undetectable
1knyB-4a5aA:
undetectable		 1knyA-4a5aA:
17.60
1knyB-4a5aA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 9 GLY A  72
ALA A  71
LEU A 152
LEU A 156
PHE A 109
 ANP  A 700 (-3.6A)
None
None
None
None
 1.02A 1nr6A-4a5aA:
undetectable		 1nr6A-4a5aA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 8 MET A 325
LEU A 335
GLY A 334
LEU A 453
 None
 0.91A 1ya4A-4a5aA:
undetectable		 1ya4A-4a5aA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 THR A 188
GLY A  72
GLY A 111
THR A  76
ILE A 231
 ANP  A 700 (-3.7A)
ANP  A 700 (-3.6A)
None
None
None
 1.35A 2akeA-4a5aA:
undetectable		 2akeA-4a5aA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 THR A 188
GLY A  72
GLY A 111
THR A  76
ILE A 231
 ANP  A 700 (-3.7A)
ANP  A 700 (-3.6A)
None
None
None
 1.34A 2azxA-4a5aA:
undetectable		 2azxA-4a5aA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 THR A 188
GLY A  72
GLY A 111
THR A  76
ILE A 231
 ANP  A 700 (-3.7A)
ANP  A 700 (-3.6A)
None
None
None
 1.30A 2azxB-4a5aA:
undetectable		 2azxB-4a5aA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		3 / 3 ALA A 497
THR A 564
PHE A 525
 None
 0.68A 2c6nB-4a5aA:
undetectable		 2c6nB-4a5aA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 9 GLY A 574
ILE A 285
THR A 490
PRO A 578
ILE A 581
 None
 1.32A 2nnhB-4a5aA:
undetectable		 2nnhB-4a5aA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		3 / 3 LEU A 310
PRO A 311
ARG A 257
 None
 0.46A 2qd4B-4a5aA:
2.8		 2qd4B-4a5aA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 10 ARG A 250
ILE A 488
GLY A 274
LEU A 567
ILE A 581
 None
 1.47A 3adsA-4a5aA:
undetectable		 3adsA-4a5aA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 ALA A 281
GLY A 279
SER A  74
GLY A  72
SER A  73
 ANP  A 700 (-4.5A)
ANP  A 700 (-3.7A)
ANP  A 700 (-2.7A)
ANP  A 700 (-3.6A)
ANP  A 700 (-2.8A)
 1.01A 3g2oA-4a5aA:
undetectable		 3g2oA-4a5aA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 ALA A 281
GLY A 279
SER A  74
GLY A  72
SER A  73
 ANP  A 700 (-4.5A)
ANP  A 700 (-3.7A)
ANP  A 700 (-2.7A)
ANP  A 700 (-3.6A)
ANP  A 700 (-2.8A)
 0.92A 3g2oB-4a5aA:
undetectable		 3g2oB-4a5aA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 4 ILE A  95
ARG A 249
ILE A 100
THR A 612
 None
 1.08A 3ia4C-4a5aA:
undetectable		 3ia4C-4a5aA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		3 / 3 ILE A  95
SER A  62
SER A  87
 None
 0.59A 3iltH-4a5aA:
undetectable		 3iltH-4a5aA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 GLU A 236
GLY A 237
GLY A 279
SER A 282
PHE A 324
 ANP  A 700 ( 4.0A)
None
ANP  A 700 (-3.7A)
ANP  A 700 (-3.6A)
None
 1.08A 3k13C-4a5aA:
undetectable		 3k13C-4a5aA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 453
GLU A 277
ALA A 283
SER A 332
MET A 329
 None
MG  A 701 (-4.7A)
None
None
ANP  A 700 (-4.8A)
 1.38A 3ou6D-4a5aA:
undetectable		 3ou6D-4a5aA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_A_NIOA311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 9 ASP A  96
LEU A 606
ASP A  98
HIS A 246
ALA A  83
 None
 1.43A 3r2jA-4a5aA:
undetectable		 3r2jA-4a5aA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 ASP A  96
LEU A 606
ASP A  98
HIS A 246
ALA A  83
 None
 1.41A 3r2jC-4a5aA:
undetectable		 3r2jC-4a5aA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 6 LEU A 335
SER A 331
ALA A 281
LEU A 389
 None
None
ANP  A 700 (-4.5A)
None
 0.97A 3ravA-4a5aA:
undetectable		 3ravA-4a5aA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 6 GLY A 603
TRP A 600
ARG A 229
GLU A 236
 None
None
None
ANP  A 700 ( 4.0A)
 1.40A 4bqfA-4a5aA:
undetectable		 4bqfA-4a5aA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 PHE A 611
LEU A 309
VAL A 302
ALA A 234
THR A 232
 None
 1.07A 4fiaA-4a5aA:
undetectable		 4fiaA-4a5aA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 PHE A 611
LEU A 309
VAL A 302
ALA A 234
THR A 232
 None
 1.07A 4fiaA-4a5aA:
undetectable		 4fiaA-4a5aA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 8 SER A 282
GLU A 277
GLN A 284
ARG A 192
 ANP  A 700 (-3.6A)
MG  A 701 (-4.7A)
None
None
 1.14A 4lnwA-4a5aA:
undetectable		 4lnwA-4a5aA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 6 SER A 282
GLU A 277
GLN A 284
ARG A 192
 ANP  A 700 (-3.6A)
MG  A 701 (-4.7A)
None
None
 1.12A 4lnxA-4a5aA:
undetectable		 4lnxA-4a5aA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 GLY A 328
ALA A 281
GLY A 279
GLY A 280
THR A  76
 None
ANP  A 700 (-4.5A)
ANP  A 700 (-3.7A)
ANP  A 700 (-3.6A)
None
 0.93A 4o33A-4a5aA:
undetectable		 4o33A-4a5aA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 GLY A 190
GLY A  72
SER A  75
SER A 282
ALA A 281
 ANP  A 700 (-4.6A)
ANP  A 700 (-3.6A)
ANP  A 700 ( 4.7A)
ANP  A 700 (-3.6A)
ANP  A 700 (-4.5A)
 1.01A 4qtuD-4a5aA:
undetectable		 4qtuD-4a5aA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 LEU A 102
GLY A 104
THR A  78
GLN A 167
LEU A 164
 None
 1.21A 5b8hA-4a5aA:
8.6
5b8hB-4a5aA:
4.2		 5b8hA-4a5aA:
22.55
5b8hB-4a5aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 GLY A 274
ALA A 273
ASP A 271
ILE A 242
ILE A 587
 None
 0.86A 5e5jB-4a5aA:
undetectable		 5e5jB-4a5aA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		3 / 3 ASP A 193
LEU A 424
ARG A 427
 None
 0.87A 5e8qA-4a5aA:
undetectable		 5e8qA-4a5aA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 6 GLU A 465
GLY A 233
ARG A 192
ARG A 229
 None
 1.49A 5jcnB-4a5aA:
undetectable		 5jcnB-4a5aA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		5 / 12 ARG A 388
LEU A 357
ALA A 496
ALA A 333
LEU A 337
 None
None
ANP  A 700 (-3.5A)
None
None
 0.93A 5jw1B-4a5aA:
undetectable		 5jw1B-4a5aA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		3 / 3 VAL A 142
LYS A 150
MET A 153
 None
 0.81A 5nknA-4a5aA:
undetectable		 5nknA-4a5aA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1
(Toxoplasma
gondii) 		4 / 4 LEU A 156
LEU A 152
SER A  75
ALA A 110
 None
None
ANP  A 700 ( 4.7A)
None
 1.11A 5uunA-4a5aA:
undetectable		 5uunA-4a5aA:
20.43