SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 9 PHE A 117
GLY A 214
ASP A 254
MET A 323
TYR A 325
ASP A 326
TRP A 486
 None
 1.12A 1e9lA-4a5qA:
33.5		 1e9lA-4a5qA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 9 TYR A  73
PHE A 117
GLY A 214
ASP A 254
TYR A 325
ASP A 326
TRP A 486
 None
 0.98A 1e9lA-4a5qA:
33.5		 1e9lA-4a5qA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 ASN A  23
ILE A 168
ASN A 169
SER A  96
 None
 0.90A 1h7xA-4a5qA:
10.8		 1h7xA-4a5qA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 ASN A  23
ILE A 168
ASN A 169
SER A  96
 None
 0.91A 1h7xB-4a5qA:
10.9		 1h7xB-4a5qA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 ASN A  23
ILE A 168
ASN A 169
SER A  96
 None
 0.90A 1h7xC-4a5qA:
6.4		 1h7xC-4a5qA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 ASN A  23
ILE A 168
ASN A 169
SER A  96
 None
 0.90A 1h7xD-4a5qA:
6.5		 1h7xD-4a5qA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 GLY A 237
LEU A 251
ILE A 212
ILE A 121
LEU A 120
 None
 1.22A 1kyvA-4a5qA:
undetectable
1kyvE-4a5qA:
undetectable		 1kyvA-4a5qA:
15.05
1kyvE-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 GLY A 319
LEU A 361
ILE A 309
ILE A 279
LEU A 312
 None
 1.22A 1kyvA-4a5qA:
undetectable
1kyvE-4a5qA:
undetectable		 1kyvA-4a5qA:
15.05
1kyvE-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 121
LEU A 120
GLY A 237
LEU A 251
ILE A 212
 None
 1.21A 1kyvB-4a5qA:
undetectable
1kyvC-4a5qA:
undetectable		 1kyvB-4a5qA:
15.05
1kyvC-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 279
LEU A 312
GLY A 319
LEU A 361
ILE A 309
 None
 1.21A 1kyvB-4a5qA:
undetectable
1kyvC-4a5qA:
undetectable		 1kyvB-4a5qA:
15.05
1kyvC-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 121
LEU A 120
GLY A 237
LEU A 251
ILE A 212
 None
 1.20A 1kyvC-4a5qA:
undetectable
1kyvD-4a5qA:
undetectable		 1kyvC-4a5qA:
15.05
1kyvD-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 279
LEU A 312
GLY A 319
LEU A 361
ILE A 309
 None
 1.23A 1kyvC-4a5qA:
undetectable
1kyvD-4a5qA:
undetectable		 1kyvC-4a5qA:
15.05
1kyvD-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 121
LEU A 120
GLY A 237
LEU A 251
ILE A 212
 None
 1.20A 1kyvD-4a5qA:
undetectable
1kyvE-4a5qA:
undetectable		 1kyvD-4a5qA:
15.05
1kyvE-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 279
LEU A 312
GLY A 319
LEU A 361
ILE A 309
 None
 1.21A 1kyvD-4a5qA:
undetectable
1kyvE-4a5qA:
undetectable		 1kyvD-4a5qA:
15.05
1kyvE-4a5qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 ASP A  81
GLU A  30
GLY A  27
ASP A 421
THR A 420
 None
 1.45A 1m4gB-4a5qA:
undetectable		 1m4gB-4a5qA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 8 ASP A  81
GLU A  30
GLY A  27
ASP A 421
THR A 420
 None
 1.45A 1m4iA-4a5qA:
undetectable		 1m4iA-4a5qA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_B_KANB501_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 ASP A  81
GLU A  30
GLY A  27
ASP A 421
THR A 420
 None
 1.41A 1m4iB-4a5qA:
0.0		 1m4iB-4a5qA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 THR A 380
GLY A 378
GLU A 418
GLU A 413
ILE A 485
 None
 1.45A 1odiC-4a5qA:
undetectable		 1odiC-4a5qA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 THR A 380
GLY A 378
GLU A 418
GLU A 413
ILE A 485
 None
 1.49A 1odiE-4a5qA:
undetectable		 1odiE-4a5qA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 THR A 380
GLY A 378
GLU A 418
GLU A 413
ILE A 485
 None
 1.49A 1odiF-4a5qA:
undetectable		 1odiF-4a5qA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
ASP A 254
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.00A 2a3aA-4a5qA:
34.3		 2a3aA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
GLY A 214
ASP A 254
ASP A 326
TYR A 379
TRP A 486
 None
 0.91A 2a3aA-4a5qA:
34.3		 2a3aA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 TYR A  73
PHE A 117
GLY A 214
ASP A 254
GLU A 256
MET A 323
ASP A 326
TYR A 379
 None
 0.81A 2a3aA-4a5qA:
34.3		 2a3aA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
GLY A 214
TRP A 215
ASP A 254
GLU A 256
MET A 323
 None
 0.90A 2a3aA-4a5qA:
34.3		 2a3aA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		3 / 3 TRP A 215
GLU A 256
TYR A 257
 None
 0.30A 2a3aA-4a5qA:
12.2		 2a3aA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		6 / 9 PHE A 117
GLY A 214
GLU A 256
MET A 323
ASP A 326
TYR A 379
 None
 0.72A 2a3aB-4a5qA:
34.6		 2a3aB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 PHE A 117
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.01A 2a3aB-4a5qA:
34.6		 2a3aB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
GLY A 214
ASP A 254
MET A 323
ASP A 326
TYR A 379
 None
 0.84A 2a3bA-4a5qA:
7.4		 2a3bA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 TYR A  73
PHE A 117
GLY A 214
TRP A 215
ASP A 254
ASP A 326
TYR A 379
TRP A 486
 None
 0.92A 2a3bA-4a5qA:
7.4		 2a3bA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
GLY A 214
TRP A 215
ASP A 254
GLU A 256
ASP A 326
 None
 0.86A 2a3bA-4a5qA:
7.4		 2a3bA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 GLU A 256
TYR A 257
ASP A 326
ARG A 381
 None
 0.82A 2a3bB-4a5qA:
12.2		 2a3bB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		6 / 10 PHE A 117
ASP A 254
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.00A 2a3bB-4a5qA:
7.1		 2a3bB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 10 PHE A 117
GLY A 214
ASP A 254
GLU A 256
MET A 323
ASP A 326
TYR A 379
 None
 0.91A 2a3bB-4a5qA:
7.1		 2a3bB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 PHE A 117
GLY A 214
ASP A 254
TYR A 379
TRP A 486
 None
 0.99A 2a3bB-4a5qA:
7.1		 2a3bB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 12 TYR A  73
PHE A 117
GLY A 214
ASP A 254
ASP A 326
TYR A 379
TRP A 486
 None
 0.89A 2a3cA-4a5qA:
7.2		 2a3cA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 12 TYR A  73
TRP A  77
PHE A 117
ASP A 254
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.04A 2a3cA-4a5qA:
7.2		 2a3cA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 12 TYR A  73
TRP A  77
PHE A 117
GLY A 214
ASP A 254
GLU A 256
MET A 323
ASP A 326
 None
 0.95A 2a3cA-4a5qA:
7.2		 2a3cA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 12 TYR A  73
TRP A  77
PHE A 117
GLY A 214
ASP A 254
MET A 323
ASP A 326
TYR A 379
 None
 0.83A 2a3cA-4a5qA:
7.2		 2a3cA-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 12 PHE A 117
GLY A 214
ASP A 254
GLU A 256
ASP A 326
TYR A 379
TRP A 486
 None
 0.99A 2a3cB-4a5qA:
34.5		 2a3cB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 12 TRP A  77
PHE A 117
ASP A 254
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.01A 2a3cB-4a5qA:
34.5		 2a3cB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 12 TRP A  77
PHE A 117
GLY A 214
ASP A 254
GLU A 256
MET A 323
ASP A 326
TYR A 379
 None
 0.86A 2a3cB-4a5qA:
34.5		 2a3cB-4a5qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 PHE A 459
ALA A 383
ALA A 405
SER A 336
LEU A 335
 None
 1.09A 2bxeB-4a5qA:
undetectable		 2bxeB-4a5qA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 ILE A 238
GLY A 316
ALA A 315
ASP A 314
ILE A 320
 None
 1.02A 2fxdA-4a5qA:
undetectable		 2fxdA-4a5qA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 HIS A 360
ASP A 355
ASP A 356
TYR A 352
 None
 1.19A 2lh8A-4a5qA:
undetectable		 2lh8A-4a5qA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 TYR A  73
PHE A 117
GLY A 214
GLU A 256
TRP A 486
 None
 0.51A 2uy4A-4a5qA:
16.8		 2uy4A-4a5qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 TYR A  73
PHE A 117
GLY A 214
GLU A 256
TRP A 486
 None
 0.65A 2xtkA-4a5qA:
17.4		 2xtkA-4a5qA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 TYR A  73
PHE A 117
GLY A 214
GLU A 256
TRP A 486
 None
 0.50A 2xtkB-4a5qA:
17.5		 2xtkB-4a5qA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 PHE A 110
PHE A  59
ALA A  97
SER A  78
SER A 487
 None
 1.29A 3apwA-4a5qA:
undetectable		 3apwA-4a5qA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 TRP A 215
ASP A 326
TYR A 352
ARG A 381
 None
 0.80A 3arqA-4a5qA:
34.2		 3arqA-4a5qA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 7 TRP A 215
ASP A 326
TYR A 352
ARG A 381
 None
 0.79A 3arrA-4a5qA:
34.7		 3arrA-4a5qA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ATT_A_ACTA1209_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 4 ASP A  64
ARG A 108
ASP A  65
GLU A  63
 None
 1.24A 3attA-4a5qA:
0.0		 3attA-4a5qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ILE A 279
ILE A 212
SER A 211
PHE A 241
ILE A 282
 None
 1.15A 3cd2A-4a5qA:
undetectable		 3cd2A-4a5qA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
ASP A 254
MET A 323
TYR A 325
ASP A 326
TYR A 379
 None
 1.05A 3g6mA-4a5qA:
10.9		 3g6mA-4a5qA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 TYR A  73
PHE A 117
GLY A 214
ASP A 254
GLU A 256
MET A 323
ASP A 326
TYR A 379
 None
 0.81A 3g6mA-4a5qA:
10.9		 3g6mA-4a5qA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 TYR A  73
PHE A 117
GLY A 214
TRP A 215
ASP A 254
ASP A 326
TYR A 379
TRP A 486
 None
 0.88A 3g6mA-4a5qA:
10.9		 3g6mA-4a5qA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 TYR A  73
PHE A 117
GLY A 214
TRP A 215
ASP A 254
GLU A 256
ASP A 326
TYR A 379
 None
 0.65A 3g6mA-4a5qA:
10.9		 3g6mA-4a5qA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 TYR A  73
PHE A 117
TRP A 215
ASP A 254
TYR A 325
ASP A 326
TYR A 379
 None
 0.91A 3g6mA-4a5qA:
10.9		 3g6mA-4a5qA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 GLY A 493
LEU A 495
ILE A 485
PHE A  59
ALA A 499
 None
 1.04A 3gwvA-4a5qA:
undetectable		 3gwvA-4a5qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ASP A 363
ILE A 320
SER A 297
LEU A 322
LEU A 480
 None
 1.16A 3k2hA-4a5qA:
undetectable		 3k2hA-4a5qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 5 VAL A 511
PHE A 517
ILE A 494
PHE A 429
 None
 0.92A 3owxB-4a5qA:
undetectable		 3owxB-4a5qA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 PHE A 248
PHE A 241
GLY A 118
THR A 155
PHE A 242
 None
 1.38A 3t3rB-4a5qA:
undetectable		 3t3rB-4a5qA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 8 PHE A 328
THR A 380
ARG A 381
SER A 350
 None
 1.08A 3tzfB-4a5qA:
7.5		 3tzfB-4a5qA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 7 ILE A 238
GLY A 237
PHE A 221
LEU A 120
 None
 0.74A 3v7pA-4a5qA:
3.5		 3v7pA-4a5qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 TYR A  80
SER A 211
TYR A 115
PHE A 196
LEU A 199
 None
 1.39A 3vw1B-4a5qA:
undetectable		 3vw1B-4a5qA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		8 / 11 PHE A 117
GLY A 214
GLU A 256
MET A 323
TYR A 325
ASP A 326
TYR A 379
ARG A 381
 None
 0.90A 3wqvA-4a5qA:
33.8		 3wqvA-4a5qA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		9 / 11 PHE A 117
GLY A 214
TRP A 215
GLU A 256
MET A 323
ASP A 326
TYR A 379
ARG A 381
TRP A 486
 None
 0.90A 3wqvA-4a5qA:
33.8		 3wqvA-4a5qA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 11 PHE A 117
GLY A 214
MET A 323
TYR A 325
ASP A 326
TYR A 379
ARG A 381
 None
 0.95A 3wqwA-4a5qA:
33.8		 3wqwA-4a5qA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		9 / 11 PHE A 117
GLY A 214
TRP A 215
GLU A 256
MET A 323
ASP A 326
TYR A 379
ARG A 381
TRP A 486
 None
 0.90A 3wqwA-4a5qA:
33.8		 3wqwA-4a5qA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4a5q CHI1
(Yersinia
entomophaga) 		3 / 3 TYR A 379
HIS A 338
ARG A 381
 None
 1.21A 4e7bC-4a5qA:
undetectable		 4e7bC-4a5qA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4a5q CHI1
(Yersinia
entomophaga) 		3 / 3 ASP A 421
ARG A 101
THR A  48
 None
 0.90A 4i13A-4a5qA:
undetectable		 4i13A-4a5qA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 4 ILE A 212
SER A 211
ASP A 123
ASP A 129
 None
 1.46A 4krhB-4a5qA:
2.3		 4krhB-4a5qA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 5 LEU A 113
LEU A  71
LEU A 102
ASN A 321
 None
 1.26A 4n09B-4a5qA:
undetectable		 4n09B-4a5qA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 9 PHE A 459
ALA A 383
ALA A 405
SER A 336
LEU A 335
 None
 1.13A 4or0A-4a5qA:
undetectable		 4or0A-4a5qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 11 ARG A 101
LEU A 102
LEU A 192
ASP A 489
LEU A 113
 None
 1.44A 4or0A-4a5qA:
undetectable		 4or0A-4a5qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 12 ASN A  69
VAL A  70
HIS A 250
ASN A 321
GLY A 292
 None
 1.17A 4qckA-4a5qA:
undetectable		 4qckA-4a5qA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 SER A  78
GLY A 213
ASP A 254
GLY A 118
 None
 0.90A 5cdpA-4a5qA:
undetectable
5cdpB-4a5qA:
undetectable		 5cdpA-4a5qA:
23.12
5cdpB-4a5qA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 7 PHE A 275
SER A 222
ALA A 225
PRO A 258
 None
 1.14A 5dzkD-4a5qA:
2.3
5dzkR-4a5qA:
undetectable		 5dzkD-4a5qA:
17.53
5dzkR-4a5qA:
1.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		3 / 3 TRP A 215
GLU A 256
ASP A 326
 None
 0.78A 5gqbA-4a5qA:
36.3		 5gqbA-4a5qA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 8 GLY A 262
TYR A 325
ASP A 326
ARG A 381
 None
 0.89A 5gqbA-4a5qA:
36.3		 5gqbA-4a5qA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		7 / 8 PHE A 117
GLY A 214
TRP A 215
GLU A 256
ASP A 326
ARG A 381
TRP A 486
 None
 0.92A 5gqbA-4a5qA:
36.3		 5gqbA-4a5qA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 8 PHE A 117
GLY A 214
TYR A 325
ASP A 326
ARG A 381
 None
 0.75A 5gqbA-4a5qA:
36.3		 5gqbA-4a5qA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 7 GLY A 119
TRP A  77
GLN A  79
ASP A 159
 None
 1.27A 5vlmG-4a5qA:
undetectable		 5vlmG-4a5qA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 4 ARG A  83
SER A 411
ASP A 421
HIS A 425
 None
 1.50A 5zhmA-4a5qA:
0.0		 5zhmA-4a5qA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 5 TYR A 426
ASN A 382
THR A 380
LEU A 462
 None
 1.43A 6d8pA-4a5qA:
1.4		 6d8pA-4a5qA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 LEU A 251
SER A 209
ILE A 212
SER A 116
GLY A 213
 None
 1.47A 6dlzA-4a5qA:
undetectable
6dlzD-4a5qA:
2.2		 6dlzA-4a5qA:
10.59
6dlzD-4a5qA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 ILE A 212
SER A 116
GLY A 213
LEU A 251
SER A 209
 None
 1.47A 6dlzB-4a5qA:
undetectable
6dlzC-4a5qA:
undetectable		 6dlzB-4a5qA:
10.59
6dlzC-4a5qA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 LEU A 251
SER A 209
ILE A 212
SER A 116
GLY A 213
 None
 1.48A 6dm1A-4a5qA:
undetectable
6dm1D-4a5qA:
undetectable		 6dm1A-4a5qA:
10.59
6dm1D-4a5qA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4a5q CHI1
(Yersinia
entomophaga) 		5 / 10 ILE A 212
SER A 116
GLY A 213
LEU A 251
SER A 209
 None
 1.48A 6dm1B-4a5qA:
undetectable
6dm1C-4a5qA:
2.2		 6dm1B-4a5qA:
10.59
6dm1C-4a5qA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 4a5q CHI1
(Yersinia
entomophaga) 		4 / 6 ALA A  97
SER A 487
GLY A 378
ILE A 423
 None
 0.82A 6f8cA-4a5qA:
undetectable		 6f8cA-4a5qA:
9.75