SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4a6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 1.12A 3ablP-4a6oA:
undetectable
3ablW-4a6oA:
undetectable		 3ablP-4a6oA:
19.10
3ablW-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 9 ALA A1318
ILE A1231
VAL A1217
GLY A1219
ILE A1336
 None
 0.88A 3s43A-4a6oA:
undetectable		 3s43A-4a6oA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		3 / 3 GLU A1282
GLY A1286
SER A1314
 None
 0.48A 4b53B-4a6oA:
2.2		 4b53B-4a6oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 4 ILE A1313
LEU A1255
LYS A1315
ASN A1258
 None
 1.35A 4g19D-4a6oA:
undetectable		 4g19D-4a6oA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.97A 5b1aC-4a6oA:
undetectable
5b1aJ-4a6oA:
undetectable		 5b1aC-4a6oA:
19.10
5b1aJ-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.97A 5b1aP-4a6oA:
undetectable
5b1aW-4a6oA:
undetectable		 5b1aP-4a6oA:
19.10
5b1aW-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.96A 5b3sC-4a6oA:
undetectable
5b3sJ-4a6oA:
undetectable		 5b3sC-4a6oA:
19.10
5b3sJ-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.94A 5b3sP-4a6oA:
undetectable		 5b3sP-4a6oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		5 / 12 ALA A1318
ILE A1231
VAL A1217
GLY A1219
ILE A1336
 None
 0.87A 5t8hB-4a6oA:
undetectable		 5t8hB-4a6oA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.97A 5z84P-4a6oA:
undetectable
5z84W-4a6oA:
undetectable		 5z84P-4a6oA:
19.10
5z84W-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.97A 5z85P-4a6oA:
undetectable
5z85W-4a6oA:
undetectable		 5z85P-4a6oA:
19.10
5z85W-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.96A 5z86C-4a6oA:
undetectable
5z86J-4a6oA:
undetectable		 5z86C-4a6oA:
19.10
5z86J-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.97A 5z86P-4a6oA:
undetectable
5z86W-4a6oA:
undetectable		 5z86P-4a6oA:
19.10
5z86W-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 1.01A 5zcoP-4a6oA:
undetectable
5zcoW-4a6oA:
undetectable		 5zcoP-4a6oA:
19.10
5zcoW-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.96A 5zcpC-4a6oA:
undetectable
5zcpJ-4a6oA:
undetectable		 5zcpC-4a6oA:
19.10
5zcpJ-4a6oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN
(Clostridium
perfringens) 		4 / 6 GLN A1276
PHE A1275
PHE A1268
LEU A1266
 None
 0.98A 5zcpP-4a6oA:
undetectable
5zcpW-4a6oA:
undetectable		 5zcpP-4a6oA:
19.10
5zcpW-4a6oA:
15.82