SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aa9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 8 PHE A  58
GLY A 104
VAL A 138
PHE A  29
 None
 0.97A 1gsfA-4aa9A:
undetectable		 1gsfA-4aa9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 8 PHE A  58
GLY A 104
VAL A 138
PHE A  29
 None
 0.97A 1gsfB-4aa9A:
undetectable		 1gsfB-4aa9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 8 PHE A  58
GLY A 104
VAL A 138
PHE A  29
 None
 0.97A 1gsfC-4aa9A:
undetectable		 1gsfC-4aa9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 8 PHE A  58
GLY A 104
VAL A 138
PHE A  29
 None
 0.97A 1gsfD-4aa9A:
undetectable		 1gsfD-4aa9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 SER A 285
GLY A 237
LEU A 253
MET A 256
ILE A 236
 None
 1.34A 1lhuA-4aa9A:
undetectable		 1lhuA-4aa9A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.79A 1muiB-4aa9A:
8.3		 1muiB-4aa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 7 THR A  92
ASN A 141
LEU A  40
GLN A 101
 None
 1.14A 1qzrA-4aa9A:
undetectable		 1qzrA-4aa9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.69A 1sdtB-4aa9A:
8.5		 1sdtB-4aa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 11 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.70A 1sdvB-4aa9A:
8.4		 1sdvB-4aa9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.74A 2avoB-4aa9A:
8.4		 2avoB-4aa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.74A 2avsB-4aa9A:
8.3		 2avsB-4aa9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.79A 2avvB-4aa9A:
8.2		 2avvB-4aa9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.75A 2bpxB-4aa9A:
7.6		 2bpxB-4aa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		3 / 3 ASP A 158
ARG A 159
ARG A 304
 None
 1.11A 2j9dA-4aa9A:
undetectable
2j9dC-4aa9A:
undetectable		 2j9dA-4aa9A:
15.48
2j9dC-4aa9A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.67A 2o4sB-4aa9A:
8.4		 2o4sB-4aa9A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.69A 2r5pB-4aa9A:
8.5		 2r5pB-4aa9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.68A 2r5pD-4aa9A:
8.6		 2r5pD-4aa9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 11 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.75A 2r5qB-4aa9A:
8.4		 2r5qB-4aa9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 10 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.76A 2r5qD-4aa9A:
8.4		 2r5qD-4aa9A:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		6 / 12 ASP A 216
GLY A 218
TYR A  11
ASP A  34
GLY A  36
SER A  38
 GOL  A1334 (-3.5A)
None
GOL  A1334 (-2.9A)
None
None
None
 1.14A 2v0zC-4aa9A:
39.2		 2v0zC-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		7 / 12 GLN A  15
ASP A  34
GLY A  36
SER A  37
ASP A 216
GLY A 218
SER A 220
 None
None
None
None
GOL  A1334 (-3.5A)
None
None
 0.98A 2v0zC-4aa9A:
39.2		 2v0zC-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		7 / 12 GLN A  15
VAL A  32
ASP A  34
GLY A  36
SER A  37
ASP A 216
GLY A 218
 None
None
None
None
None
GOL  A1334 (-3.5A)
None
 1.15A 2v0zC-4aa9A:
39.2		 2v0zC-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		7 / 12 VAL A  32
ASP A  34
GLY A  36
SER A  37
PHE A 119
ASP A 216
GLY A 218
 None
None
None
None
None
GOL  A1334 (-3.5A)
None
 0.54A 2v0zC-4aa9A:
39.2		 2v0zC-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		6 / 12 GLN A  15
ASP A  34
GLY A  36
ASP A 216
GLY A 218
SER A 220
 None
None
None
GOL  A1334 (-3.5A)
None
None
 1.00A 2v0zO-4aa9A:
39.9		 2v0zO-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		6 / 12 GLN A  15
VAL A  32
ASP A  34
GLY A  36
ASP A 216
GLY A 218
 None
None
None
None
GOL  A1334 (-3.5A)
None
 1.13A 2v0zO-4aa9A:
39.9		 2v0zO-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		6 / 12 VAL A  32
ASP A  34
GLY A  36
PHE A 119
ASP A 216
GLY A 218
 None
None
None
None
GOL  A1334 (-3.5A)
None
 0.53A 2v0zO-4aa9A:
39.9		 2v0zO-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 GLN A  15
ASP A  34
GLY A  36
ASP A 216
SER A 220
 None
None
None
GOL  A1334 (-3.5A)
None
 0.86A 3d91A-4aa9A:
39.2		 3d91A-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 GLN A  15
ASP A  34
GLY A  36
PHE A  17
ASP A 216
 None
None
None
None
GOL  A1334 (-3.5A)
 0.80A 3d91A-4aa9A:
39.2		 3d91A-4aa9A:
36.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 GLN A  15
ASP A  34
GLY A  36
ASP A 216
SER A 220
 None
None
None
GOL  A1334 (-3.5A)
None
 1.04A 3d91B-4aa9A:
39.1		 3d91B-4aa9A:
36.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 4 ARG A 312
ASP A 144
ASP A 140
PRO A 128
 None
 1.19A 3fgrB-4aa9A:
undetectable		 3fgrB-4aa9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 4 ARG A 312
ASP A 144
ASP A 140
PRO A 137
 None
 1.39A 3fgrB-4aa9A:
undetectable		 3fgrB-4aa9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 5 LYS A  71
PRO A  72
SER A  74
SER A 135
 None
None
SO4  A1332 (-4.8A)
None
 1.32A 3ijxH-4aa9A:
undetectable		 3ijxH-4aa9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 5 LYS A  71
PRO A  72
SER A  74
SER A 135
 None
None
SO4  A1332 (-4.8A)
None
 1.36A 3iluH-4aa9A:
undetectable		 3iluH-4aa9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 11 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.89A 3ndxB-4aa9A:
8.2		 3ndxB-4aa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A  39
ILE A  75
ILE A 122
 None
None
None
SO4  A1332 (-4.4A)
None
 0.73A 3nu5B-4aa9A:
8.2		 3nu5B-4aa9A:
18.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A 216
THR A 219
ILE A 297
 None
None
GOL  A1334 (-3.5A)
None
GOL  A1334 (-4.2A)
 0.37A 3prsA-4aa9A:
35.8		 3prsA-4aa9A:
30.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ASP A 216
THR A 219
ILE A 297
 None
None
GOL  A1334 (-3.5A)
None
GOL  A1334 (-4.2A)
 0.36A 3q70A-4aa9A:
11.8		 3q70A-4aa9A:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ILE A 214
ASP A 216
GLY A 218
ASP A  34
ILE A 122
 None
GOL  A1334 (-3.5A)
None
None
None
 0.61A 3q70A-4aa9A:
11.8		 3q70A-4aa9A:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 6 LEU A 270
VAL A 259
PHE A 287
VAL A 301
 None
 1.06A 3soaA-4aa9A:
undetectable		 3soaA-4aa9A:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ILE A  75
ASP A 216
ILE A 297
 None
None
SO4  A1332 (-4.4A)
GOL  A1334 (-3.5A)
GOL  A1334 (-4.2A)
 0.54A 3tneA-4aa9A:
33.2		 3tneA-4aa9A:
31.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ILE A 214
ASP A 216
GLY A 218
ASP A  34
ILE A 122
 None
GOL  A1334 (-3.5A)
None
None
None
 0.63A 3tneA-4aa9A:
33.2		 3tneA-4aa9A:
31.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ASP A  34
GLY A  36
ILE A  75
ASP A 216
ILE A 297
 None
None
SO4  A1332 (-4.4A)
GOL  A1334 (-3.5A)
GOL  A1334 (-4.2A)
 0.58A 3tneB-4aa9A:
33.1		 3tneB-4aa9A:
31.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		5 / 12 ILE A 214
ASP A 216
GLY A 218
ASP A  34
ILE A 122
 None
GOL  A1334 (-3.5A)
None
None
None
 0.63A 3tneB-4aa9A:
33.1		 3tneB-4aa9A:
31.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		4 / 7 GLY A 121
ILE A 122
VAL A  93
VAL A  91
 None
 0.79A 3ufnB-4aa9A:
8.8		 3ufnB-4aa9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4aa9 CHYMOSIN
(Camelus
dromedarius) 		3 / 3 ARG A 150
LEU A 152
PHE A 310
 SO4  A1327 (-4.1A)
None
None
 0.66A 6nknP-4aa9A:
undetectable		 6nknP-4aa9A:
18.29