SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 ALA A  42
VAL A  40
TRP A 499
 None
 0.94A 1jnoA-4aahA:
undetectable		 1jnoA-4aahA:
2.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 ALA A  42
VAL A  40
TRP A 499
 None
 0.94A 1jnoB-4aahA:
undetectable		 1jnoB-4aahA:
2.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 7 PHE A 501
PRO A 504
ALA A  42
PHE A 569
 None
 1.16A 1lqtA-4aahA:
undetectable		 1lqtA-4aahA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 7 PHE A 501
PRO A 504
ALA A  42
PHE A 569
 None
 1.15A 1lquA-4aahA:
undetectable		 1lquA-4aahA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 7 ILE A 508
PRO A 532
PHE A 553
ALA A 465
 None
 1.10A 1oniG-4aahA:
undetectable
1oniI-4aahA:
undetectable		 1oniG-4aahA:
13.39
1oniI-4aahA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 252
ASN A 302
SER A 510
GLN A 303
HIS A 321
 None
 1.39A 1qu3A-4aahA:
undetectable		 1qu3A-4aahA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 LEU A 483
PRO A 511
SER A 524
GLY A 389
 None
 1.09A 2qd5A-4aahA:
undetectable		 2qd5A-4aahA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 LYS A 121
HIS A  68
ASP A 108
ALA A  17
 None
 1.05A 2rk8A-4aahA:
undetectable		 2rk8A-4aahA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 TRP A 458
VAL A 305
ARG A 333
 None
 0.88A 3b0wA-4aahA:
undetectable		 3b0wA-4aahA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 GLY A 509
GLY A 389
GLY A 468
 None
 0.41A 3bogC-4aahA:
undetectable		 3bogC-4aahA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 GLY A 509
GLY A 389
GLY A 468
 None
 0.35A 3bogD-4aahA:
undetectable		 3bogD-4aahA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ALA A 549
GLY A 551
LEU A 540
LEU A 429
GLY A 533
 None
 1.06A 3g2oA-4aahA:
undetectable		 3g2oA-4aahA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ALA A 549
GLY A 551
LEU A 540
LEU A 429
GLY A 533
 None
 1.08A 3g2oB-4aahA:
undetectable		 3g2oB-4aahA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ILE A 327
GLY A 326
ALA A 347
VAL A 348
ASN A 349
 None
 1.10A 3jb3A-4aahA:
undetectable		 3jb3A-4aahA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 PHE A 351
TRP A 296
GLY A 546
ALA A 549
ILE A 407
 None
 1.21A 3ld6B-4aahA:
undetectable		 3ld6B-4aahA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 6 LEU A 111
TYR A 113
ALA A 129
LEU A  59
 None
 1.14A 3rd0A-4aahA:
undetectable		 3rd0A-4aahA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 ASP A 297
GLY A 300
GLU A 171
ARG A 109
 CA  A 702 (-3.6A)
None
CA  A 702 ( 2.3A)
PQQ  A 701 (-3.6A)
 0.99A 3s3mA-4aahA:
undetectable		 3s3mA-4aahA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 4 GLY A 507
GLY A 485
THR A 560
LEU A 556
 None
 0.78A 3si7C-4aahA:
undetectable
3si7D-4aahA:
undetectable		 3si7C-4aahA:
18.78
3si7D-4aahA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 5 LEU A 556
GLY A 507
GLY A 485
THR A 560
 None
 0.80A 3si7C-4aahA:
undetectable
3si7D-4aahA:
undetectable		 3si7C-4aahA:
18.78
3si7D-4aahA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ASN A 387
HIS A 386
GLY A 403
ALA A  57
GLY A  56
 PQQ  A 701 (-3.5A)
None
None
None
None
 1.15A 3v3oA-4aahA:
undetectable		 3v3oA-4aahA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ASN A 387
HIS A 386
GLY A 403
ALA A  57
GLY A  56
 PQQ  A 701 (-3.5A)
None
None
None
None
 1.20A 3v3oB-4aahA:
undetectable		 3v3oB-4aahA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 TYR A  66
MET A  65
ILE A 522
 None
 0.88A 4c8bB-4aahA:
undetectable		 4c8bB-4aahA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ASP A 323
ASN A 302
GLY A 254
ASN A 255
ARG A 264
 None
None
None
CA  A 702 ( 3.0A)
None
 1.32A 4djeB-4aahA:
undetectable		 4djeB-4aahA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 11 ALA A 170
GLY A 233
GLY A 252
ASN A 255
TRP A 237
 PQQ  A 701 (-3.4A)
None
None
CA  A 702 ( 3.0A)
PQQ  A 701 (-3.4A)
 1.31A 4jdsA-4aahA:
undetectable		 4jdsA-4aahA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 11 ALA A 170
GLY A 233
GLY A 252
ASN A 255
TRP A 237
 PQQ  A 701 (-3.4A)
None
None
CA  A 702 ( 3.0A)
PQQ  A 701 (-3.4A)
 1.29A 4jdsB-4aahA:
undetectable		 4jdsB-4aahA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 THR A 513
LEU A 471
VAL A  40
VAL A  37
 None
 1.04A 4l4bA-4aahA:
undetectable		 4l4bA-4aahA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 234
GLY A 176
THR A 271
ASN A 255
GLY A 252
 None
None
None
CA  A 702 ( 3.0A)
None
 1.02A 4n48A-4aahA:
undetectable		 4n48A-4aahA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 234
GLY A 176
THR A 271
ASN A 255
GLY A 252
 None
None
None
CA  A 702 ( 3.0A)
None
 1.00A 4n48B-4aahA:
undetectable		 4n48B-4aahA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 6 PHE A 449
ASP A 345
LEU A 404
THR A 459
 None
 1.30A 4paeA-4aahA:
undetectable		 4paeA-4aahA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 ALA A 132
GLY A 114
ALA A 112
ASP A   3
LEU A   4
 None
 1.14A 5c0oE-4aahA:
undetectable		 5c0oE-4aahA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 6 GLY A 196
THR A 195
SER A 200
VAL A 201
 None
 1.15A 5ewuA-4aahA:
undetectable		 5ewuA-4aahA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 MET A 525
HIS A  68
GLY A  53
 None
 0.87A 5gwzB-4aahA:
undetectable		 5gwzB-4aahA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 563
GLN A 388
VAL A 390
GLY A 506
LEU A  51
 None
PQQ  A 701 ( 4.8A)
None
None
None
 1.09A 5hg0A-4aahA:
undetectable		 5hg0A-4aahA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 564
GLN A 388
VAL A 390
GLY A 506
LEU A  51
 None
PQQ  A 701 ( 4.8A)
None
None
None
 1.03A 5hg0A-4aahA:
undetectable		 5hg0A-4aahA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 GLY A 254
ALA A 257
ASP A 297
ASN A 236
 None
None
CA  A 702 (-3.6A)
None
 0.97A 5mvsB-4aahA:
undetectable		 5mvsB-4aahA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		4 / 8 ALA A  57
VAL A  40
GLN A 520
HIS A  25
 None
 0.83A 5nu7A-4aahA:
undetectable		 5nu7A-4aahA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 233
LYS A 230
ASP A 294
GLY A 300
SER A 253
 None
 1.16A 5vooD-4aahA:
undetectable		 5vooD-4aahA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 233
LYS A 230
ASP A 294
GLY A 300
SER A 253
 None
 1.14A 5vooF-4aahA:
undetectable		 5vooF-4aahA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		3 / 3 MET A 272
ASP A 297
ARG A 109
 None
CA  A 702 (-3.6A)
PQQ  A 701 (-3.6A)
 1.14A 5z6kA-4aahA:
undetectable		 5z6kA-4aahA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 10 GLY A 254
GLY A 300
ASP A 297
THR A 271
ASN A 268
 None
None
CA  A 702 (-3.6A)
None
None
 1.18A 6exiA-4aahA:
undetectable		 6exiA-4aahA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 10 GLY A 254
GLY A 300
ASP A 297
THR A 271
ASN A 268
 None
None
CA  A 702 (-3.6A)
None
None
 1.18A 6exiB-4aahA:
undetectable		 6exiB-4aahA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 254
GLY A 300
ASP A 297
THR A 271
ASN A 268
 None
None
CA  A 702 (-3.6A)
None
None
 1.19A 6exiC-4aahA:
undetectable
6exiD-4aahA:
undetectable		 6exiC-4aahA:
9.09
6exiD-4aahA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 12 GLY A 254
GLY A 300
ASP A 297
THR A 271
ASN A 268
 None
None
CA  A 702 (-3.6A)
None
None
 1.17A 6exiC-4aahA:
undetectable
6exiD-4aahA:
undetectable		 6exiC-4aahA:
9.09
6exiD-4aahA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 4aah METHANOL
DEHYDROGENASE
(Methylophilus
methylotrophus) 		5 / 11 GLY A 548
GLY A 546
VAL A 534
MET A 431
ASP A 297
 None
None
None
None
CA  A 702 (-3.6A)
 1.16A 6i5zD-4aahA:
undetectable		 6i5zD-4aahA:
22.58