SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4abn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 SER A 203
GLU A 237
GLU A 238
GLU A 411
 None
 0.87A 1knyA-4abnA:
2.2
1knyB-4abnA:
3.4		 1knyA-4abnA:
19.79
1knyB-4abnA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		5 / 12 LEU A 416
VAL A 384
PHE A 355
VAL A 369
THR A 412
 None
 1.14A 1q23B-4abnA:
undetectable		 1q23B-4abnA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		5 / 11 LEU A 416
VAL A 384
PHE A 355
VAL A 369
THR A 412
 None
 1.06A 1q23F-4abnA:
undetectable		 1q23F-4abnA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.94A 1v55C-4abnA:
3.4
1v55J-4abnA:
undetectable		 1v55C-4abnA:
19.53
1v55J-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.98A 1v55P-4abnA:
3.3
1v55W-4abnA:
undetectable		 1v55P-4abnA:
19.53
1v55W-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		5 / 11 ALA A 206
ALA A 209
ALA A 168
SER A 191
LEU A 190
 None
EDO  A1433 ( 4.7A)
None
None
None
 1.09A 2bxeB-4abnA:
2.0		 2bxeB-4abnA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.98A 2dysC-4abnA:
3.4
2dysJ-4abnA:
undetectable		 2dysC-4abnA:
19.53
2dysJ-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 1.00A 2dysP-4abnA:
3.6
2dysW-4abnA:
undetectable		 2dysP-4abnA:
19.53
2dysW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.93A 2eijC-4abnA:
3.4
2eijJ-4abnA:
undetectable		 2eijC-4abnA:
19.53
2eijJ-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 1.03A 2eijP-4abnA:
3.3
2eijW-4abnA:
undetectable		 2eijP-4abnA:
19.53
2eijW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.98A 2eimC-4abnA:
2.9
2eimJ-4abnA:
undetectable		 2eimC-4abnA:
19.53
2eimJ-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.95A 2eimP-4abnA:
3.3
2eimW-4abnA:
undetectable		 2eimP-4abnA:
19.53
2eimW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 1.02A 2einC-4abnA:
3.3
2einJ-4abnA:
undetectable		 2einC-4abnA:
19.53
2einJ-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		3 / 3 TRP A 182
ALA A 220
VAL A 216
 None
 0.97A 2izqC-4abnA:
undetectable
2izqD-4abnA:
undetectable		 2izqC-4abnA:
2.39
2izqD-4abnA:
2.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 5 ALA A 220
ASP A  28
ASP A  21
ASP A 178
 None
 1.06A 2nyuB-4abnA:
undetectable		 2nyuB-4abnA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		3 / 3 ASN A 107
ASN A 141
ARG A 180
 None
 0.65A 2rlcA-4abnA:
undetectable		 2rlcA-4abnA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.96A 3asnP-4abnA:
3.2
3asnW-4abnA:
undetectable		 3asnP-4abnA:
19.53
3asnW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 1.00A 3asoP-4abnA:
3.3
3asoW-4abnA:
undetectable		 3asoP-4abnA:
19.53
3asoW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		5 / 12 LEU A 274
LEU A 271
LEU A 268
ALA A 243
THR A 354
 None
 0.87A 4fn9A-4abnA:
undetectable		 4fn9A-4abnA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 6 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.99A 5w97C-4abnA:
3.3
5w97J-4abnA:
undetectable		 5w97C-4abnA:
19.53
5w97J-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		4 / 7 LYS A 281
PHE A 355
LEU A 274
PHE A 405
 None
 0.99A 5x1fP-4abnA:
undetectable
5x1fW-4abnA:
undetectable		 5x1fP-4abnA:
19.53
5x1fW-4abnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4abn TETRATRICOPEPTIDE
REPEAT PROTEIN 5
(Mus
musculus) 		5 / 11 VAL A 337
THR A 335
VAL A 341
LEU A 357
VAL A 417
 None
 1.34A 6dryA-4abnA:
2.8		 6dryA-4abnA:
21.62