SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4abx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4abx DNA REPAIR PROTEIN
RECN
(Deinococcus
radiodurans) 		5 / 10 ASP A 314
LEU A 313
LEU A 226
SER A 324
LEU A 323
 None
 1.15A 4zbrA-4abxA:
3.6		 4zbrA-4abxA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4abx DNA REPAIR PROTEIN
RECN
(Deinococcus
radiodurans) 		4 / 8 ASP A 252
GLU A 304
ASP A 301
GLU A 298
 None
 1.25A 6mn4B-4abxA:
undetectable		 6mn4B-4abxA:
21.37