SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		7 / 12 HIS A 294
TYR A 296
ASP A 442
GLU A 471
ASP A 536
ASP A 579
ARG A 583
 None
 1.02A 1dedA-4aeeA:
37.4		 1dedA-4aeeA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		7 / 12 HIS A 294
TYR A 296
ASP A 442
HIS A 535
ASP A 536
ASP A 579
ARG A 583
 None
 0.67A 1dedA-4aeeA:
37.4		 1dedA-4aeeA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		8 / 12 HIS A 294
TYR A 296
ARG A 440
ASP A 442
GLU A 471
HIS A 535
ASP A 536
ARG A 583
 None
 0.73A 1dedB-4aeeA:
34.1		 1dedB-4aeeA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 GLY A 261
ASP A 305
ILE A 287
ILE A 231
ILE A 233
 None
 0.90A 1hshC-4aeeA:
undetectable		 1hshC-4aeeA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		7 / 12 TYR A 296
HIS A 336
ARG A 440
ASP A 442
GLU A 471
HIS A 535
ASP A 536
 None
 0.44A 1mxdA-4aeeA:
26.7		 1mxdA-4aeeA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		7 / 12 TYR A 296
HIS A 336
PHE A 404
ARG A 440
ASP A 442
HIS A 535
ASP A 536
 None
 0.66A 1mxdA-4aeeA:
26.7		 1mxdA-4aeeA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 6 LEU A 148
ASP A 150
LEU A 151
GLY A 152
 None
 0.90A 1n13H-4aeeA:
undetectable
1n13K-4aeeA:
undetectable		 1n13H-4aeeA:
9.05
1n13K-4aeeA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 LEU A 148
ASP A 150
LEU A 151
GLY A 152
 None
 0.93A 1n13G-4aeeA:
undetectable
1n13J-4aeeA:
undetectable		 1n13G-4aeeA:
6.89
1n13J-4aeeA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.80A 1rtsA-4aeeA:
undetectable		 1rtsA-4aeeA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.85A 1rtsB-4aeeA:
undetectable		 1rtsB-4aeeA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 TYR A 229
GLY A 569
GLY A 573
ILE A 231
PHE A 236
 None
 1.41A 2akeA-4aeeA:
undetectable		 2akeA-4aeeA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 TYR A 489
TYR A 283
TYR A 296
HIS A 535
 None
 1.27A 2bteA-4aeeA:
undetectable		 2bteA-4aeeA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 TYR A 489
TYR A 283
TYR A 296
HIS A 535
 None
 1.28A 2bteD-4aeeA:
undetectable		 2bteD-4aeeA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 TYR A 489
TYR A 283
TYR A 296
HIS A 535
 None
 1.21A 2bytA-4aeeA:
undetectable		 2bytA-4aeeA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 TYR A 489
TYR A 283
TYR A 296
HIS A 535
 None
 1.22A 2bytD-4aeeA:
undetectable		 2bytD-4aeeA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 6 ARG A 183
SER A 205
SER A 201
GLU A 198
 None
 1.29A 2c8aC-4aeeA:
undetectable		 2c8aC-4aeeA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 11 TYR A 229
GLY A 569
GLY A 573
ILE A 231
PHE A 236
 None
 1.41A 2dr2A-4aeeA:
undetectable		 2dr2A-4aeeA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ARG A 386
ASP A 297
GLY A 258
TYR A 259
 None
 1.05A 2f6dA-4aeeA:
undetectable		 2f6dA-4aeeA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 PHE A 558
TYR A 529
PRO A 564
THR A 226
 None
 1.49A 2q6kA-4aeeA:
undetectable		 2q6kA-4aeeA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.83A 2tsrA-4aeeA:
undetectable		 2tsrA-4aeeA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 167
ILE A 139
ARG A 477
TRP A  63
 None
 1.06A 2v57A-4aeeA:
undetectable		 2v57A-4aeeA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 167
ILE A 139
ARG A 477
TRP A  63
 None
 1.05A 2v57C-4aeeA:
undetectable		 2v57C-4aeeA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 10 ILE A 135
ILE A 173
SER A 613
ILE A 635
TYR A 517
 None
 1.18A 2w9sC-4aeeA:
undetectable		 2w9sC-4aeeA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASP A 237
TYR A 260
ARG A 248
GLY A 261
 None
 0.97A 2ys6A-4aeeA:
undetectable		 2ys6A-4aeeA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.18A 3aicA-4aeeA:
6.3		 3aicA-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.22A 3aicB-4aeeA:
6.3		 3aicB-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		7 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
TYR A 296
 None
 1.16A 3aicC-4aeeA:
4.1		 3aicC-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.25A 3aicD-4aeeA:
6.3		 3aicD-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.21A 3aicE-4aeeA:
6.2		 3aicE-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.21A 3aicF-4aeeA:
3.2		 3aicF-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.21A 3aicG-4aeeA:
6.3		 3aicG-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 ARG A 440
ASP A 442
GLU A 471
ARG A 492
HIS A 535
ASP A 536
 None
 1.21A 3aicH-4aeeA:
6.3		 3aicH-4aeeA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 PHE A 360
THR A 298
ILE A 427
MET A 334
THR A 333
 None
 1.11A 3czhA-4aeeA:
undetectable		 3czhA-4aeeA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 PHE A 360
THR A 298
ILE A 427
MET A 334
THR A 333
 None
 1.17A 3dl9B-4aeeA:
undetectable		 3dl9B-4aeeA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 ARG A 386
ASP A 579
GLN A 230
 None
 0.93A 3lcvB-4aeeA:
undetectable		 3lcvB-4aeeA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 168
VAL A 169
GLY A 165
TYR A  67
PRO A  64
 None
 0.96A 3mb5A-4aeeA:
undetectable		 3mb5A-4aeeA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 5 ASP A 570
LEU A 574
ILE A 231
PHE A 232
 None
 1.02A 3s3vA-4aeeA:
undetectable		 3s3vA-4aeeA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 495
ALA A 559
LEU A 644
LEU A 629
ILE A 631
 None
 0.92A 3uvvA-4aeeA:
undetectable		 3uvvA-4aeeA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 233
LEU A 308
ILE A 304
ILE A 282
LEU A 330
 None
 1.00A 3vrmA-4aeeA:
undetectable		 3vrmA-4aeeA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 10 ALA A 494
ARG A 512
LEU A 556
LEU A 491
ASN A 515
 None
 1.07A 3wdmB-4aeeA:
undetectable		 3wdmB-4aeeA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 10 ALA A 494
ARG A 512
LEU A 556
LEU A 491
ASN A 515
 None
 1.07A 3wdmD-4aeeA:
undetectable		 3wdmD-4aeeA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 TYR A 517
HIS A 162
ARG A 137
 None
 1.09A 4e7bC-4aeeA:
undetectable		 4e7bC-4aeeA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 TYR A 568
TYR A 567
LEU A 574
ASN A 582
 None
 1.35A 4f8yC-4aeeA:
undetectable
4f8yD-4aeeA:
undetectable		 4f8yC-4aeeA:
13.27
4f8yD-4aeeA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 GLU A 575
ASN A 592
TRP A 593
ILE A 572
 None
 0.95A 4ii8A-4aeeA:
undetectable		 4ii8A-4aeeA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.86A 4iqqB-4aeeA:
undetectable		 4iqqB-4aeeA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.83A 4iqqC-4aeeA:
undetectable		 4iqqC-4aeeA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 118
ILE A 174
LEU A 180
ILE A 149
ASN A 187
 None
 1.13A 4o1eA-4aeeA:
9.3		 4o1eA-4aeeA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 11 LEU A 472
PHE A 483
ASP A 484
ALA A 486
ILE A 459
 None
 1.37A 4uuuA-4aeeA:
undetectable
4uuuB-4aeeA:
undetectable		 4uuuA-4aeeA:
10.78
4uuuB-4aeeA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.15A 4v2yA-4aeeA:
undetectable		 4v2yA-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.15A 4v2yB-4aeeA:
undetectable		 4v2yB-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 0.96A 4v2yC-4aeeA:
undetectable		 4v2yC-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.17A 4v2zA-4aeeA:
undetectable		 4v2zA-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.15A 4v2zB-4aeeA:
undetectable		 4v2zB-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 0.98A 4v2zC-4aeeA:
undetectable		 4v2zC-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.17A 4v30A-4aeeA:
undetectable		 4v30A-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.17A 4v30B-4aeeA:
undetectable		 4v30B-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
PHE A 424
 None
 1.23A 4v32A-4aeeA:
undetectable		 4v32A-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
PHE A 424
 None
 1.26A 4v32B-4aeeA:
undetectable		 4v32B-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.02A 5amhA-4aeeA:
undetectable		 5amhA-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.18A 5amiA-4aeeA:
undetectable		 5amiA-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.17A 5amiB-4aeeA:
undetectable		 5amiB-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.14A 5amjA-4aeeA:
undetectable		 5amjA-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.13A 5amjB-4aeeA:
undetectable		 5amjB-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ARG A 440
ASP A 442
GLU A 471
HIS A 535
ASP A 536
 None
 0.42A 5csyB-4aeeA:
2.1		 5csyB-4aeeA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 LEU A 597
ILE A 271
PHE A 236
GLY A 266
MET A 586
 None
 1.20A 5eshA-4aeeA:
undetectable		 5eshA-4aeeA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.86A 5h3aB-4aeeA:
undetectable		 5h3aB-4aeeA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 6 ASP A 272
ILE A 267
TYR A 229
TYR A 598
 None
 1.36A 5igyA-4aeeA:
undetectable		 5igyA-4aeeA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 6 ASP A 272
HIS A 270
TYR A 229
TYR A 598
 None
 1.28A 5ih0A-4aeeA:
3.0		 5ih0A-4aeeA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.82A 5nooA-4aeeA:
undetectable		 5nooA-4aeeA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.85A 5nooB-4aeeA:
undetectable		 5nooB-4aeeA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 LYS A 412
HIS A 415
HIS A 335
 None
 1.13A 5oexA-4aeeA:
undetectable		 5oexA-4aeeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 LYS A 412
HIS A 415
HIS A 335
 None
 1.20A 5oexB-4aeeA:
2.9		 5oexB-4aeeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 LYS A 412
HIS A 415
HIS A 335
 None
 1.19A 5oexC-4aeeA:
2.8		 5oexC-4aeeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		3 / 3 LYS A 412
HIS A 415
HIS A 335
 None
 1.17A 5oexD-4aeeA:
2.0		 5oexD-4aeeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.16A 5oh1A-4aeeA:
undetectable		 5oh1A-4aeeA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.20A 5oh1B-4aeeA:
undetectable		 5oh1B-4aeeA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.19A 5oh1C-4aeeA:
undetectable		 5oh1C-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.13A 5oh3A-4aeeA:
undetectable		 5oh3A-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ASN A 338
PRO A 339
PHE A 344
TYR A 423
 None
 1.18A 5oh3B-4aeeA:
undetectable		 5oh3B-4aeeA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 GLU A 622
VAL A 621
HIS A 162
PRO A 561
GLY A 617
 None
 1.02A 5syeB-4aeeA:
3.2		 5syeB-4aeeA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 7 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.78A 5x5qC-4aeeA:
undetectable		 5x5qC-4aeeA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.80A 5x5qD-4aeeA:
undetectable		 5x5qD-4aeeA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 6 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.80A 5x5qE-4aeeA:
undetectable		 5x5qE-4aeeA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		4 / 8 ILE A 447
LEU A 472
GLY A 470
TYR A 489
 None
 0.80A 5x5qF-4aeeA:
undetectable		 5x5qF-4aeeA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 TYR A 296
HIS A 336
GLU A 474
ASP A 442
HIS A 535
ASP A 536
 None
 1.11A 6ag0A-4aeeA:
22.5		 6ag0A-4aeeA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 TYR A 296
HIS A 336
MET A 410
ASP A 442
HIS A 535
ASP A 536
 None
 1.29A 6ag0A-4aeeA:
22.5		 6ag0A-4aeeA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		6 / 12 LEU A 264
ILE A 267
GLY A 266
ILE A 287
ASP A 234
ILE A 233
 None
 1.21A 6emuA-4aeeA:
2.6		 6emuA-4aeeA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 267
GLY A 266
ILE A 287
ASP A 234
ILE A 233
 None
 1.07A 6emuB-4aeeA:
undetectable		 6emuB-4aeeA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4aee ALPHA AMYLASE,
CATALYTIC REGION
(Staphylothermus
marinus) 		5 / 12 ILE A 267
GLY A 266
ILE A 287
ASP A 234
ILE A 233
 None
 1.05A 6emuC-4aeeA:
undetectable		 6emuC-4aeeA:
14.85