SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4aey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4aey	D-ERYTHRO-7,8-DIHYDR ONEOPTERIN TRIPHOSPHATE EPIMERASE (Pseudomonas aeruginosa)	5 / 11	ILE A 68 THR A 64 ILE A 86 ASN A 38 ILE A 37	None	1.07A	3kpcA-4aeyA: undetectable	3kpcA-4aeyA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_B_SAMB1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4aey	D-ERYTHRO-7,8-DIHYDR ONEOPTERIN TRIPHOSPHATE EPIMERASE (Pseudomonas aeruginosa)	5 / 12	ILE A 68 THR A 64 ILE A 86 ASN A 38 ILE A 37	None	1.03A	3kpdB-4aeyA: undetectable	3kpdB-4aeyA: 18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_C_SAMC1000_1 (UNCHARACTERIZED PROTEIN MJ0100)	4aey	D-ERYTHRO-7,8-DIHYDR ONEOPTERIN TRIPHOSPHATE EPIMERASE (Pseudomonas aeruginosa)	6 / 12	ILE A 68 THR A 64 ILE A 86 ASN A 38 ILE A 37 VAL A 71	None	1.39A	3kpdC-4aeyA: undetectable	3kpdC-4aeyA: 18.99